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Items: 10

1.

Amaryllidaceae Alkaloids as Potential Glycogen Synthase Kinase-3β Inhibitors.

Hulcová D, Breiterová K, Siatka T, Klímová K, Davani L, Šafratová M, Hošťálková A, De Simone A, Andrisano V, Cahlíková L.

Molecules. 2018 Mar 21;23(4). pii: E719. doi: 10.3390/molecules23040719.

2.

Alkaloids from Narcissus poeticus cv. Pink Parasol of various structural types and their biological activity.

Šafratová M, Hošťálková A, Hulcová D, Breiterová K, Hrabcová V, Machado M, Fontinha D, Prudêncio M, Kuneš J, Chlebek J, Jun D, Hrabinová M, Nováková L, Havelek R, Seifrtová M, Opletal L, Cahlíková L.

Arch Pharm Res. 2018 Feb;41(2):208-218. doi: 10.1007/s12272-017-1000-4. Epub 2017 Dec 14.

PMID:
29243039
3.

Anticancer potential of Amaryllidaceae alkaloids evaluated by screening with a panel of human cells, real-time cellular analysis and Ehrlich tumor-bearing mice.

Havelek R, Muthna D, Tomsik P, Kralovec K, Seifrtova M, Cahlikova L, Hostalkova A, Safratova M, Perwein M, Cermakova E, Rezacova M.

Chem Biol Interact. 2017 Sep 25;275:121-132. doi: 10.1016/j.cbi.2017.07.018. Epub 2017 Jul 26.

PMID:
28756149
4.

Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets.

Chlebek J, De Simone A, Hošťálková A, Opletal L, Pérez C, Pérez DI, Havlíková L, Cahlíková L, Andrisano V.

Fitoterapia. 2016 Mar;109:241-7. doi: 10.1016/j.fitote.2016.01.008. Epub 2016 Jan 11.

PMID:
26779945
5.

LC-MS/MS method for the determination of haemanthamine in rat plasma, bile and urine and its application to a pilot pharmacokinetic study.

Hroch M, Mičuda S, Havelek R, Cermanová J, Cahlíková L, Hošťálková A, Hulcová D, Řezáčová M.

Biomed Chromatogr. 2016 Jul;30(7):1083-1091. doi: 10.1002/bmc.3653. Epub 2015 Dec 13.

PMID:
26577707
6.

Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment.

Zemanova L, Hofman J, Novotna E, Musilek K, Lundova T, Havrankova J, Hostalkova A, Chlebek J, Cahlikova L, Wsol V.

J Nat Prod. 2015 Nov 25;78(11):2666-74. doi: 10.1021/acs.jnatprod.5b00616. Epub 2015 Nov 3.

PMID:
26529431
7.

Isoquinoline alkaloids as prolyl oligopeptidase inhibitors.

Cahlíková L, Hulová L, Hrabinová M, Chlebek J, Hošťálková A, Adamcová M, Šafratová M, Jun D, Opletal L, Ločárek M, Macáková K.

Fitoterapia. 2015 Jun;103:192-6. doi: 10.1016/j.fitote.2015.04.004. Epub 2015 Apr 9.

PMID:
25863351
8.

Isoquinoline alkaloids as a novel type of AKR1C3 inhibitors.

Skarydova L, Hofman J, Chlebek J, Havrankova J, Kosanova K, Skarka A, Hostalkova A, Plucha T, Cahlikova L, Wsol V.

J Steroid Biochem Mol Biol. 2014 Sep;143:250-8. doi: 10.1016/j.jsbmb.2014.04.005. Epub 2014 Apr 24.

PMID:
24769118
9.

Comparison of an HPTLC method with the Reflectoquant assay for rapid determination of 5-hydroxymethylfurfural in honey.

Hošťálková A, Klingelhöfer I, Morlock GE.

Anal Bioanal Chem. 2013 Nov;405(28):9207-18. doi: 10.1007/s00216-013-7339-6. Epub 2013 Oct 5.

PMID:
24091734
10.

Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Chelidonium majus (Papaveraceae).

Cahlíková L, Opletal L, Kurfürst M, Macáková K, Kulhánková A, Hostálková A.

Nat Prod Commun. 2010 Nov;5(11):1751-4.

PMID:
21213973

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