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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1854 1
1889 1
1945 1
1946 2
1947 1
1948 2
1949 2
1950 1
1951 4
1952 1
1953 3
1954 1
1956 1
1958 1
1959 4
1960 4
1961 1
1962 4
1963 10
1964 16
1965 9
1966 4
1967 4
1968 5
1969 9
1970 6
1971 8
1972 8
1973 12
1974 6
1975 14
1976 16
1977 18
1978 16
1979 17
1980 21
1981 40
1982 61
1983 82
1984 119
1985 132
1986 164
1987 147
1988 221
1989 238
1990 262
1991 239
1992 310
1993 345
1994 364
1995 423
1996 454
1997 527
1998 579
1999 584
2000 628
2001 706
2002 705
2003 761
2004 841
2005 954
2006 962
2007 1037
2008 1173
2009 1237
2010 1410
2011 1468
2012 1693
2013 1770
2014 2122
2015 2348
2016 2430
2017 2632
2018 2707
2019 2872
2020 3355
2021 3692
2022 3443
2023 3367
2024 1188

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45,446 results

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Page 1
Impact of Angiopoietin-2 on Kidney Diseases.
Li M, Popovic Z, Chu C, Reichetzeder C, Pommer W, Krämer BK, Hocher B. Li M, et al. Kidney Dis (Basel). 2023 Mar 14;9(3):0. doi: 10.1159/000529774. eCollection 2023 May. Kidney Dis (Basel). 2023. PMID: 38306230 Free PMC article. Review.
The most studied angiopoietins, angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2), behave antagonistically to each other in vivo to sustain vascular endothelium homeostasis. ...However, the exact mechanisms of Ang-2 action in renal diseases remain unclear. KE …
The most studied angiopoietins, angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2), behave antagonistically to each other in vi …
Erythropoietin Regulation by Angiotensin II.
Kim YC, Mungunsukh O, Day RM. Kim YC, et al. Vitam Horm. 2017;105:57-77. doi: 10.1016/bs.vh.2017.02.001. Epub 2017 Mar 27. Vitam Horm. 2017. PMID: 28629525 Review.
In contrast, angiotensin II (Ang II) that has a variety of biological functions in the cells is converted from Ang I through removal of two-C-terminal residues by ACE. ...To modulate RAS, three classes of drugs have been developed: (1) renin inhibitors to prevent an …
In contrast, angiotensin II (Ang II) that has a variety of biological functions in the cells is converted from Ang I through r …
The role of Ang/Tie signaling in lymphangiogenesis.
Wu X, Liu N. Wu X, et al. Lymphology. 2010 Jun;43(2):59-72. Lymphology. 2010. PMID: 20848993 Review.
The best characterized angiopoietins are Ang-1 and Ang-2. Ang-1 acts as an obligate agonist of the Tie2 receptor. ...In the presence of VEGF-A, Ang-2 promotes vascular sprouting. When in the absence of VEGF-A, Ang-2 induces vascular regression. …
The best characterized angiopoietins are Ang-1 and Ang-2. Ang-1 acts as an obligate agonist of the Tie2 receptor. ...In …
Cardiovascular actions of angiotensin-(1-7).
Ferreira AJ, Santos RA. Ferreira AJ, et al. Braz J Med Biol Res. 2005 Apr;38(4):499-507. doi: 10.1590/s0100-879x2005000400003. Epub 2005 Apr 13. Braz J Med Biol Res. 2005. PMID: 15962175 Free article. Review.
Chronic administration of angiotensin-converting enzyme inhibitors (ACEI) increases 10- to 25-fold the plasma levels of this peptide, suggesting that part of the beneficial effects of ACEI could be mediated by Ang-(1-7). Ang-(1-7) can be formed from Ang II or …
Chronic administration of angiotensin-converting enzyme inhibitors (ACEI) increases 10- to 25-fold the plasma levels of this peptide, sugges …
Angiotensin-converting enzyme 2-Angiotensin 1-7/1-9 system: novel promising targets for heart failure treatment.
Kittana N. Kittana N. Fundam Clin Pharmacol. 2018 Feb;32(1):14-25. doi: 10.1111/fcp.12318. Epub 2017 Dec 1. Fundam Clin Pharmacol. 2018. PMID: 28833476 Review.
Ang I and Ang II may also be converted into angiotensin 1-7 (Ang 1-7) and angiotensin 1-9 (Ang 1-9), respectively, by the action of angiotensin-converting enzyme 2. Both derivatives demonstrated a promising anticardiac remodeling activity especially ag …
Ang I and Ang II may also be converted into angiotensin 1-7 (Ang 1-7) and angiotensin 1-9 (Ang 1-9), respectivel …
ACE2: more of Ang-(1-7) or less Ang II?
Ferrario CM. Ferrario CM. Curr Opin Nephrol Hypertens. 2011 Jan;20(1):1-6. doi: 10.1097/MNH.0b013e3283406f57. Curr Opin Nephrol Hypertens. 2011. PMID: 21045683 Free PMC article. Review.
PURPOSE OF REVIEW: Previous concepts regarding the pathways involved in the generation of angiotensin II (Ang II) have been challenged by studies showing the existence of a peptide acting as an endogenous antagonist of Ang II. The discovery that angiotensin-(1-7) [ …
PURPOSE OF REVIEW: Previous concepts regarding the pathways involved in the generation of angiotensin II (Ang II) have been challenge …
Angiotensin-(1-7) and its effects in the kidney.
Dilauro M, Burns KD. Dilauro M, et al. ScientificWorldJournal. 2009 Jun 30;9:522-35. doi: 10.1100/tsw.2009.70. ScientificWorldJournal. 2009. PMID: 19578709 Free PMC article. Review.
Within the kidneys, Ang-(1-7) is generated by angiotensin-converting enzyme 2 (ACE2)-mediated degradation of Ang II, sequential cleavage of the precursor angiotensin I (Ang I) by ACE2 and ACE, or the actions of brush-border membrane peptidases on Ang I …
Within the kidneys, Ang-(1-7) is generated by angiotensin-converting enzyme 2 (ACE2)-mediated degradation of Ang II, sequentia …
Role of Angiopoietins in Development of Cancer and Neoplasia Associated with Viral Infection.
Yu X, Ye F. Yu X, et al. Cells. 2020 Feb 18;9(2):457. doi: 10.3390/cells9020457. Cells. 2020. PMID: 32085414 Free PMC article. Review.
In healthy people, the Ang-1 level is sustained while Ang-2 expression is restricted. In cancer patients, Ang-2 level is elevated, which correlates with poor prognosis. ...Multiple Ang-2 inhibitors exhibit remarkable anti-tumor activities, further high …
In healthy people, the Ang-1 level is sustained while Ang-2 expression is restricted. In cancer patients, Ang-2 level i …
ACE and ACE2 in kidney disease.
Mizuiri S, Ohashi Y. Mizuiri S, et al. World J Nephrol. 2015 Feb 6;4(1):74-82. doi: 10.5527/wjn.v4.i1.74. World J Nephrol. 2015. PMID: 25664248 Free PMC article. Review.
The classical angiotensin-converting enzyme (ACE)-angiotensin II (Ang II)-Ang II type 1 (AT1) axis is considered to control the effects of RAS activation on renal disease. ...In the kidneys, ACE2 is expressed in the proximal tubules and less strongly in the glomerul …
The classical angiotensin-converting enzyme (ACE)-angiotensin II (Ang II)-Ang II type 1 (AT1) axis is considered to control th …
Angiotensin II, NADPH oxidase, and redox signaling in the vasculature.
Nguyen Dinh Cat A, Montezano AC, Burger D, Touyz RM. Nguyen Dinh Cat A, et al. Antioxid Redox Signal. 2013 Oct 1;19(10):1110-20. doi: 10.1089/ars.2012.4641. Epub 2012 Jun 11. Antioxid Redox Signal. 2013. PMID: 22530599 Free PMC article. Review.
The diverse actions of Ang II are mediated via Ang II type 1 and Ang II type 2 receptors, which couple to various signaling molecules, including NADPH oxidase (Nox), which generates reactive oxygen species (ROS). ...CRITICAL ISSUES: Although there is much evi …
The diverse actions of Ang II are mediated via Ang II type 1 and Ang II type 2 receptors, which couple to various signa …
45,446 results
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