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Items: 15

1.

Anti-Cancer Activity of Phenyl and Pyrid-2-yl 1,3-Substituted Benzo[1,2,4]triazin-7-ones and Stable Free Radical Precursors.

Keane LJ, Mirallai SI, Sweeney M, Carty MP, Zissimou GA, Berezin AA, Koutentis PA, Aldabbagh F.

Molecules. 2018 Mar 3;23(3). pii: E574. doi: 10.3390/molecules23030574.

2.

Preparation of Blatter Radicals via Aza-Wittig Chemistry: The Reaction of N-Aryliminophosphoranes with 1-(Het)aroyl-2-aryldiazenes.

Savva AC, Mirallai SI, Zissimou GA, Berezin AA, Demetriades M, Kourtellaris A, Constantinides CP, Nicolaides C, Trypiniotis T, Koutentis PA.

J Org Chem. 2017 Jul 21;82(14):7564-7575. doi: 10.1021/acs.joc.7b01297. Epub 2017 Jun 29.

PMID:
28628743
3.

Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition.

Sweeney M, Coyle R, Kavanagh P, Berezin AA, Lo Re D, Zissimou GA, Koutentis PA, Carty MP, Aldabbagh F.

Bioorg Med Chem. 2016 Aug 15;24(16):3565-70. doi: 10.1016/j.bmc.2016.05.066. Epub 2016 May 30.

PMID:
27290691
4.

The Suppression of Columnar π-Stacking in 3-Adamantyl-1-phenyl-1,4-dihydrobenzo[e][1,2,4]triazin-4-yl.

Constantinides CP, Berezin AA, Zissimou GA, Manoli M, Leitus GM, Koutentis PA.

Molecules. 2016 May 14;21(5). pii: E636. doi: 10.3390/molecules21050636.

5.

Correction to Tetraphenylhexaazaanthracenes: 16π Weakly Antiaromatic Species with Singlet Ground States.

Constantinides CP, Zissimou GA, Berezin AA, Ioannou TA, Manoli M, Tsokkou D, Theodorou E, Hayes SC, Koutentis PA.

Org Lett. 2016 Feb 19;18(4):888. doi: 10.1021/acs.orglett.6b00218. Epub 2016 Feb 4. No abstract available.

PMID:
26844383
6.

Correction to Route to Benzo- and Pyrido-Fused 1,2,4-Triazinyl Radicals via N'-(Het)aryl-N'-[2-nitro(het)aryl]hydrazides.

Berezin AA, Zissimou G, Constantinides CP, Beldjoudi Y, Rawson JM, Koutentis PA.

J Org Chem. 2015 Sep 4;80(17):8943-4. doi: 10.1021/acs.joc.5b01915. Epub 2015 Aug 27. No abstract available.

PMID:
26313535
7.

Tetraphenylhexaazaanthracenes: 16π Weakly Antiaromatic Species with Singlet Ground States.

Constantinides CP, Zissimou GA, Berezin AA, Ioannou TA, Manoli M, Tsokkou D, Theodorou E, Hayes SC, Koutentis PA.

Org Lett. 2015 Aug 21;17(16):4026-9. doi: 10.1021/acs.orglett.5b01923. Epub 2015 Aug 5. Erratum in: Org Lett. 2016 Feb 19;18(4):888.

PMID:
26244376
8.

Rational synthesis of AB-type N-substituted core-functionalized naphthalene diimides (cNDIs).

Berezin AA, Sciutto A, Demitri N, Bonifazi D.

Org Lett. 2015 Apr 17;17(8):1870-3. doi: 10.1021/acs.orglett.5b00543. Epub 2015 Mar 30.

PMID:
25822286
9.

A magnetostructural investigation of an abrupt spin transition for 1-phenyl-3-trifluoromethyl-1,4-dihydrobenzo[e][1,2,4]triazin-4-yl.

Constantinides CP, Berezin AA, Zissimou GA, Manoli M, Leitus GM, Bendikov M, Probert MR, Rawson JM, Koutentis PA.

J Am Chem Soc. 2014 Aug 27;136(34):11906-9. doi: 10.1021/ja5063746. Epub 2014 Aug 15.

PMID:
25093450
10.

Structural, magnetic, and computational correlations of some imidazolo-fused 1,2,4-benzotriazinyl radicals.

Constantinides CP, Berezin AA, Manoli M, Leitus GM, Zissimou GA, Bendikov M, Rawson JM, Koutentis PA.

Chemistry. 2014 Apr 25;20(18):5388-96. doi: 10.1002/chem.201304538. Epub 2014 Mar 20.

PMID:
24652752
11.

Ring contraction of 1,3-diphenylbenzo[1,2,4]triazinyl radicals to 1,2-diphenylbenzimidazoles.

Berezin AA, Koutentis PA.

Org Biomol Chem. 2014 Mar 14;12(10):1641-8. doi: 10.1039/c3ob42130a.

PMID:
24477224
12.

Route to benzo- and pyrido-fused 1,2,4-triazinyl radicals via N'-(het)aryl-N'-[2-nitro(het)aryl]hydrazides.

Berezin AA, Zissimou G, Constantinides CP, Beldjoudi Y, Rawson JM, Koutentis PA.

J Org Chem. 2014 Jan 3;79(1):314-27. doi: 10.1021/jo402481t. Epub 2013 Dec 18. Erratum in: J Org Chem. 2015 Sep 4;80(17):8943-4.

PMID:
24350615
13.

Synthesis and properties of imidazolo-fused benzotriazinyl radicals.

Berezin AA, Constantinides CP, Mirallai SI, Manoli M, Cao LL, Rawson JM, Koutentis PA.

Org Biomol Chem. 2013 Oct 21;11(39):6780-95. doi: 10.1039/c3ob41169a. Erratum in: Org Biomol Chem. 2014 Sep 7;12(33):6527-9.

PMID:
24175326
14.

Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase.

Catto M, Berezin AA, Lo Re D, Loizou G, Demetriades M, De Stradis A, Campagna F, Koutentis PA, Carotti A.

Eur J Med Chem. 2012 Dec;58:84-97. doi: 10.1016/j.ejmech.2012.10.003. Epub 2012 Oct 11.

PMID:
23108363
15.

From Blatter radical to 7-substituted 1,3-diphenyl-1,4-dihydrothiazolo[5',4':4,5]benzo[1,2-e][1,2,4]triazin-4-yls: toward multifunctional materials.

Berezin AA, Constantinides CP, Drouza C, Manoli M, Koutentis PA.

Org Lett. 2012 Nov 2;14(21):5586-9. doi: 10.1021/ol302714j. Epub 2012 Oct 24.

PMID:
23095002

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