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Items: 1 to 20 of 120


Adoptive CD8+ T cell therapy against cancer:Challenges and opportunities.

Jiang X, Xu J, Liu M, Xing H, Wang Z, Huang L, Mellor AL, Wang W, Wu S.

Cancer Lett. 2019 Oct 10;462:23-32. doi: 10.1016/j.canlet.2019.07.017. Epub 2019 Jul 26.


IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.

Metz R, Smith C, DuHadaway JB, Chandler P, Baban B, Merlo LMF, Pigott E, Keough MP, Rust S, Mellor AL, Mandik-Nayak L, Muller AJ, Prendergast GC.

Int Immunol. 2019 Mar 5;31(3):181-182. doi: 10.1093/intimm/dxz003. No abstract available.


Graph comparison via the nonbacktracking spectrum.

Mellor A, Grusovin A.

Phys Rev E. 2019 May;99(5-1):052309. doi: 10.1103/PhysRevE.99.052309.


Immune control by amino acid catabolism during tumorigenesis and therapy.

Lemos H, Huang L, Prendergast GC, Mellor AL.

Nat Rev Cancer. 2019 Mar;19(3):162-175. doi: 10.1038/s41568-019-0106-z. Review.


Metabolic requirements for expanding and arming a clone army.

Mellor AL, Huang L.

Nat Immunol. 2019 Feb;20(2):118-120. doi: 10.1038/s41590-018-0299-4. No abstract available.


Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?

Mellor AL, Lemos H, Huang L.

Front Immunol. 2017 Oct 27;8:1360. doi: 10.3389/fimmu.2017.01360. eCollection 2017. Review.


Direct Visualization of Au Atoms Bound to TiO2(110) O-Vacancies.

Mellor A, Humphrey D, Yim CM, Pang CL, Idriss H, Thornton G.

J Phys Chem C Nanomater Interfaces. 2017 Nov 9;121(44):24721-24725. doi: 10.1021/acs.jpcc.7b09608. Epub 2017 Oct 18.


IDO Immune Status after Chemoradiation May Predict Survival in Lung Cancer Patients.

Wang W, Huang L, Jin JY, Jolly S, Zang Y, Wu H, Yan L, Pi W, Li L, Mellor AL, Kong FS.

Cancer Res. 2018 Feb 1;78(3):809-816. doi: 10.1158/0008-5472.CAN-17-2995. Epub 2017 Nov 8.


Carbidopa, a drug in use for management of Parkinson disease inhibits T cell activation and autoimmunity.

Zhu H, Lemos H, Bhatt B, Islam BN, Singh A, Gurav A, Huang L, Browning DD, Mellor A, Fulzele S, Singh N.

PLoS One. 2017 Sep 12;12(9):e0183484. doi: 10.1371/journal.pone.0183484. eCollection 2017.


Heterogeneous out-of-equilibrium nonlinear q-voter model with zealotry.

Mellor A, Mobilia M, Zia RK.

Phys Rev E. 2017 Jan;95(1-1):012104. doi: 10.1103/PhysRevE.95.012104. Epub 2017 Jan 4.


Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes.

Horvatinovich JM, Grogan EW, Norris M, Steinkasserer A, Lemos H, Mellor AL, Tcherepanova IY, Nicolette CA, DeBenedette MA.

J Immunol. 2017 Mar 15;198(6):2286-2301. doi: 10.4049/jimmunol.1600802. Epub 2017 Feb 13.


Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase.

Huang L, Ou R, Rabelo de Souza G, Cunha TM, Lemos H, Mohamed E, Li L, Pacholczyk G, Randall J, Munn DH, Mellor AL.

PLoS Pathog. 2016 May 11;12(5):e1005615. doi: 10.1371/journal.ppat.1005615. eCollection 2016 May.


Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity.

Hong Y, Manoharan I, Suryawanshi A, Shanmugam A, Swafford D, Ahmad S, Chinnadurai R, Manicassamy B, He Y, Mellor AL, Thangaraju M, Munn DH, Manicassamy S.

Oncoimmunology. 2015 Dec 14;5(4):e1115941. eCollection 2016 Apr.


STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation.

Lemos H, Mohamed E, Huang L, Ou R, Pacholczyk G, Arbab AS, Munn D, Mellor AL.

Cancer Res. 2016 Apr 15;76(8):2076-81. doi: 10.1158/0008-5472.CAN-15-1456. Epub 2016 Mar 10.


IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance.

Munn DH, Mellor AL.

Trends Immunol. 2016 Mar;37(3):193-207. doi: 10.1016/ Epub 2016 Jan 31. Review.


The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment.

Sharma MD, Shinde R, McGaha TL, Huang L, Holmgaard RB, Wolchok JD, Mautino MR, Celis E, Sharpe AH, Francisco LM, Powell JD, Yagita H, Mellor AL, Blazar BR, Munn DH.

Sci Adv. 2015 Nov 6;1(10):e1500845. doi: 10.1126/sciadv.1500845. eCollection 2015 Nov.


Influence of Luddism on innovation diffusion.

Mellor A, Mobilia M, Redner S, Rucklidge AM, Ward JA.

Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Jul;92(1):012806. Epub 2015 Jul 10.


Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy.

Chaudhary K, Shinde R, Liu H, Gnana-Prakasam JP, Veeranan-Karmegam R, Huang L, Ravishankar B, Bradley J, Kvirkvelia N, McMenamin M, Xiao W, Kleven D, Mellor AL, Madaio MP, McGaha TL.

J Immunol. 2015 Jun 15;194(12):5713-24. doi: 10.4049/jimmunol.1500277. Epub 2015 May 15.


Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation.

Suryawanshi A, Manoharan I, Hong Y, Swafford D, Majumdar T, Taketo MM, Manicassamy B, Koni PA, Thangaraju M, Sun Z, Mellor AL, Munn DH, Manicassamy S.

J Immunol. 2015 Apr 1;194(7):3295-304. doi: 10.4049/jimmunol.1402691. Epub 2015 Feb 20.


IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.

Paschall AV, Zhang R, Qi CF, Bardhan K, Peng L, Lu G, Yang J, Merad M, McGaha T, Zhou G, Mellor A, Abrams SI, Morse HC 3rd, Ozato K, Xiong H, Liu K.

J Immunol. 2015 Mar 1;194(5):2369-79. doi: 10.4049/jimmunol.1402412. Epub 2015 Feb 2.

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