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Items: 1 to 20 of 221

1.

Smac mimetics LCL161 and GDC-0152 inhibit osteosarcoma growth and metastasis in mice.

Shekhar TM, Burvenich IJG, Harris MA, Rigopoulos A, Zanker D, Spurling A, Parker BS, Walkley CR, Scott AM, Hawkins CJ.

BMC Cancer. 2019 Sep 14;19(1):924. doi: 10.1186/s12885-019-6103-5.

2.

Current Development of Monoclonal Antibodies in Cancer Therapy.

Parakh S, King D, Gan HK, Scott AM.

Recent Results Cancer Res. 2020;214:1-70. doi: 10.1007/978-3-030-23765-3_1. Review.

PMID:
31473848
3.

Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope.

Orellana L, Thorne AH, Lema R, Gustavsson J, Parisian AD, Hospital A, Cordeiro TN, Bernadó P, Scott AM, Brun-Heath I, Lindahl E, Cavenee WK, Furnari FB, Orozco M.

Proc Natl Acad Sci U S A. 2019 May 14;116(20):10009-10018. doi: 10.1073/pnas.1821442116. Epub 2019 Apr 26.

PMID:
31028138
4.

Epidermal growth factor receptor (EGFR)-targeted therapies in mesothelioma.

Chia PL, Scott AM, John T.

Expert Opin Drug Deliv. 2019 Apr;16(4):441-451. doi: 10.1080/17425247.2019.1598374. Epub 2019 Apr 18.

PMID:
30916586
5.

The Contribution of Multiparametric Pelvic and Whole-Body MRI to Interpretation of 18F-Fluoromethylcholine or 68Ga-HBED-CC PSMA-11 PET/CT in Patients with Biochemical Failure After Radical Prostatectomy.

Metser U, Chua S, Ho B, Punwani S, Johnston E, Pouliot F, Tau N, Hawsawy A, Anconina R, Bauman G, Hicks RJ, Weickhardt A, Davis ID, Pond G, Scott AM, Tunariu N, Sidhu H, Emmett L.

J Nucl Med. 2019 Sep;60(9):1253-1258. doi: 10.2967/jnumed.118.225185. Epub 2019 Mar 22.

PMID:
30902875
6.

Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumors and metastases.

Yap ML, McFadyen JD, Wang X, Ziegler M, Chen YC, Willcox A, Nowell CJ, Scott AM, Sloan EK, Hogarth PM, Pietersz GA, Peter K.

Theranostics. 2019 Feb 7;9(4):1154-1169. doi: 10.7150/thno.29146. eCollection 2019.

7.

Assessment of Simplified Methods for Quantification of 18F-FDHT Uptake in Patients with Metastatic Castration-Resistant Prostate Cancer.

Kramer GM, Yaqub M, Vargas HA, Schuit RC, Windhorst AD, van den Eertwegh AJM, van der Veldt AAM, Bergman AM, Burnazi EM, Lewis JS, Chua S, Staton KD, Beattie BJ, Humm JL, Davis ID, Weickhardt AJ, Scott AM, Morris MJ, Hoekstra OS, Lammertsma AA.

J Nucl Med. 2019 Sep;60(9):1221-1227. doi: 10.2967/jnumed.118.220111. Epub 2019 Mar 8.

PMID:
30850488
8.

Comparison of Biomarker Assays for EGFR: Implications for Precision Medicine in Patients with Glioblastoma.

Lassman AB, Roberts-Rapp L, Sokolova I, Song M, Pestova E, Kular R, Mullen C, Zha Z, Lu X, Gomez E, Bhathena A, Maag D, Kumthekar P, Gan HK, Scott AM, Guseva M, Holen KD, Ansell PJ, van den Bent MJ.

Clin Cancer Res. 2019 Jun 1;25(11):3259-3265. doi: 10.1158/1078-0432.CCR-18-3034. Epub 2019 Feb 22.

PMID:
30796037
9.

Prospective, Multisite, International Comparison of 18F-Fluoromethylcholine PET/CT, Multiparametric MRI, and 68Ga-HBED-CC PSMA-11 PET/CT in Men with High-Risk Features and Biochemical Failure After Radical Prostatectomy: Clinical Performance and Patient Outcomes.

Emmett L, Metser U, Bauman G, Hicks RJ, Weickhardt A, Davis ID, Punwani S, Pond G, Chua S, Ho B, Johnston E, Pouliot F, Scott AM.

J Nucl Med. 2019 Jun;60(6):794-800. doi: 10.2967/jnumed.118.220103. Epub 2018 Nov 15.

PMID:
30442757
10.

Molecular Imaging Using PET/CT for Radiation Therapy Planning for Adult Cancers: Current Status and Expanding Applications.

McKay MJ, Taubman KL, Foroudi F, Lee ST, Scott AM.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):783-791. doi: 10.1016/j.ijrobp.2018.03.013. Epub 2018 Mar 21. Review.

PMID:
30353883
11.

Confocal Microscopy Reveals Cell Surface Receptor Aggregation Through Image Correlation Spectroscopy.

Parslow AC, Clayton AHA, Lock P, Scott AM.

J Vis Exp. 2018 Aug 2;(138). doi: 10.3791/57164.

PMID:
30124657
12.

Development of monoclonal anti-PDGF-CC antibodies as tools for investigating human tissue expression and for blocking PDGF-CC induced PDGFRα signalling in vivo.

Li H, Zeitelhofer M, Nilsson I, Liu X, Allan L, Gloria B, Perani A, Murone C, Catimel B, Neville AM, Scott FE, Scott AM, Eriksson U.

PLoS One. 2018 Jul 27;13(7):e0201089. doi: 10.1371/journal.pone.0201089. eCollection 2018.

13.

Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature.

Nadebaum DP, Lee ST, Nikfarjam M, Scott AM.

World J Nucl Med. 2018 Jul-Sep;17(3):195-197. doi: 10.4103/wjnm.WJNM_38_17.

14.

Preclinical toxicological assessment of a novel monoclonal antibody targeting human platelet-derived growth factor CC (PDGF-CC) in PDGF-CChum mice.

Zeitelhofer M, Li H, Adzemovic MZ, Nilsson I, Muhl L, Scott AM, Eriksson U.

PLoS One. 2018 Jul 18;13(7):e0200649. doi: 10.1371/journal.pone.0200649. eCollection 2018.

15.

Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.

Binder ZA, Thorne AH, Bakas S, Wileyto EP, Bilello M, Akbari H, Rathore S, Ha SM, Zhang L, Ferguson CJ, Dahiya S, Bi WL, Reardon DA, Idbaih A, Felsberg J, Hentschel B, Weller M, Bagley SJ, Morrissette JJD, Nasrallah MP, Ma J, Zanca C, Scott AM, Orellana L, Davatzikos C, Furnari FB, O'Rourke DM.

Cancer Cell. 2018 Jul 9;34(1):163-177.e7. doi: 10.1016/j.ccell.2018.06.006.

16.

Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.

Lassman AB, van den Bent MJ, Gan HK, Reardon DA, Kumthekar P, Butowski N, Lwin Z, Mikkelsen T, Nabors LB, Papadopoulos KP, Penas-Prado M, Simes J, Wheeler H, Walbert T, Scott AM, Gomez E, Lee HJ, Roberts-Rapp L, Xiong H, Ansell PJ, Bain E, Holen KD, Maag D, Merrell R.

Neuro Oncol. 2019 Jan 1;21(1):106-114. doi: 10.1093/neuonc/noy091.

17.

Monoclonal antibodies as immunomodulatory therapy against cancer and autoimmune diseases.

Hafeez U, Gan HK, Scott AM.

Curr Opin Pharmacol. 2018 Aug;41:114-121. doi: 10.1016/j.coph.2018.05.010. Epub 2018 Jun 5. Review.

PMID:
29883853
18.

Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.

Burvenich IJG, Farrugia W, Liu Z, Makris D, King D, Gloria B, Perani A, Allan LC, Scott AM, Ramsland PA.

Biochem J. 2018 Jul 5;475(13):2179-2190. doi: 10.1042/BCJ20180139.

PMID:
29794155
19.

Nuclear medicine in the era of personalised medicine.

Lee ST, Scott AM.

Intern Med J. 2018 May;48(5):497-499. doi: 10.1111/imj.13789. No abstract available.

PMID:
29722186
20.

Sociability in Fruit Flies: Genetic Variation, Heritability and Plasticity.

Scott AM, Dworkin I, Dukas R.

Behav Genet. 2018 May;48(3):247-258. doi: 10.1007/s10519-018-9901-7. Epub 2018 Apr 23.

PMID:
29682673

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