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Items: 18


Subtle Changes in the Levels of BCL-2 Proteins Cause Severe Craniofacial Abnormalities.

Grabow S, Kueh AJ, Ke F, Vanyai HK, Sheikh BN, Dengler MA, Chiang W, Eccles S, Smyth IM, Jones LK, de Sauvage FJ, Scott M, Whitehead L, Voss AK, Strasser A.

Cell Rep. 2018 Sep 18;24(12):3285-3295.e4. doi: 10.1016/j.celrep.2018.08.048.


TRIM17 and TRIM28 antagonistically regulate the ubiquitination and anti-apoptotic activity of BCL2A1.

Lionnard L, Duc P, Brennan MS, Kueh AJ, Pal M, Guardia F, Mojsa B, Damiano MA, Mora S, Lassot I, Ravichandran R, Cochet C, Aouacheria A, Potts PR, Herold MJ, Desagher S, Kucharczak J.

Cell Death Differ. 2018 Jul 24. doi: 10.1038/s41418-018-0169-5. [Epub ahead of print]


Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins.

Trezise S, Karnowski A, Fedele PL, Mithraprabhu S, Liao Y, D'Costa K, Kueh AJ, Hardy MP, Owczarek CM, Herold MJ, Spencer A, Shi W, Willis SN, Nutt SL, Corcoran LM.

Int J Mol Sci. 2018 Jul 24;19(8). pii: E2161. doi: 10.3390/ijms19082161.


DNA repair processes are critical mediators of p53-dependent tumor suppression.

Janic A, Valente LJ, Wakefield MJ, Di Stefano L, Milla L, Wilcox S, Yang H, Tai L, Vandenberg CJ, Kueh AJ, Mizutani S, Brennan MS, Schenk RL, Lindqvist LM, Papenfuss AT, O'Connor L, Strasser A, Herold MJ.

Nat Med. 2018 Jul;24(7):947-953. doi: 10.1038/s41591-018-0043-5. Epub 2018 Jun 11.


CRISPR/Cas9: A tool for immunological research.

Hochheiser K, Kueh AJ, Gebhardt T, Herold MJ.

Eur J Immunol. 2018 Apr;48(4):576-583. doi: 10.1002/eji.201747131. Epub 2018 Feb 26. Review.


An update on using CRISPR/Cas9 in the one-cell stage mouse embryo for generating complex mutant alleles.

Kueh AJ, Pal M, Tai L, Liao Y, Smyth GK, Shi W, Herold MJ.

Cell Death Differ. 2017 Oct;24(10):1821-1822. doi: 10.1038/cdd.2017.122. Epub 2017 Jul 28. No abstract available.


DR5 and caspase-8 are dispensable in ER stress-induced apoptosis.

Glab JA, Doerflinger M, Nedeva C, Jose I, Mbogo GW, Paton JC, Paton AW, Kueh AJ, Herold MJ, Huang DC, Segal D, Brumatti G, Puthalakath H.

Cell Death Differ. 2017 May;24(5):944-950. doi: 10.1038/cdd.2017.53. Epub 2017 Apr 14.


A non-canonical function of Ezh2 preserves immune homeostasis.

Vasanthakumar A, Xu D, Lun AT, Kueh AJ, van Gisbergen KP, Iannarella N, Li X, Yu L, Wang D, Williams BR, Lee SC, Majewski IJ, Godfrey DI, Smyth GK, Alexander WS, Herold MJ, Kallies A, Nutt SL, Allan RS.

EMBO Rep. 2017 Apr;18(4):619-631. doi: 10.15252/embr.201643237. Epub 2017 Feb 21.


Male sterility in Mcl-1-flox mice is not due to enhanced Mcl1 protein stability.

Ah-Cann C, Tailler M, Kueh AJ, Herold MJ, Opferman JT, Asselin-Labat ML, Bouillet P.

Cell Death Dis. 2016 Dec 1;7(12):e2490. doi: 10.1038/cddis.2016.391. No abstract available.


Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM.

Rohrbeck L, Gong JN, Lee EF, Kueh AJ, Behren A, Tai L, Lessene G, Huang DC, Fairlie WD, Strasser A, Herold MJ.

Cell Death Differ. 2016 Dec;23(12):2054-2062. doi: 10.1038/cdd.2016.96. Epub 2016 Sep 30.


Using CRISPR/Cas9 Technology for Manipulating Cell Death Regulators.

Kueh AJ, Herold MJ.

Methods Mol Biol. 2016;1419:253-64. doi: 10.1007/978-1-4939-3581-9_18.


Cortical Layer Inversion and Deregulation of Reelin Signaling in the Absence of SOCS6 and SOCS7.

Lawrenson ID, Krebs DL, Linossi EM, Zhang JG, McLennan TJ, Collin C, McRae HM, Kolesnik TB, Koh K, Britto JM, Kueh AJ, Sheikh BN, El-Saafin F, Nicola NA, Tan SS, Babon JJ, Nicholson SE, Alexander WS, Thomas T, Voss AK.

Cereb Cortex. 2017 Jan 1;27(1):576-588. doi: 10.1093/cercor/bhv253.


MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo.

Sheikh BN, Downer NL, Phipson B, Vanyai HK, Kueh AJ, McCarthy DJ, Smyth GK, Thomas T, Voss AK.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5437-42. doi: 10.1073/pnas.1422872112. Epub 2015 Apr 14.


An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo.

Aubrey BJ, Kelly GL, Kueh AJ, Brennan MS, O'Connor L, Milla L, Wilcox S, Tai L, Strasser A, Herold MJ.

Cell Rep. 2015 Mar 3;10(8):1422-32. doi: 10.1016/j.celrep.2015.02.002. Epub 2015 Feb 26.


Excessive versus physiologically relevant levels of retinoic acid in embryonic stem cell differentiation.

Sheikh BN, Downer NL, Kueh AJ, Thomas T, Voss AK.

Stem Cells. 2014 Jun;32(6):1451-8. doi: 10.1002/stem.1604.


Chromatin immunoprecipitation of mouse embryos.

Voss AK, Dixon MP, McLennan T, Kueh AJ, Thomas T.

Methods Mol Biol. 2012;809:335-52. doi: 10.1007/978-1-61779-376-9_23.


HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.

Kueh AJ, Dixon MP, Voss AK, Thomas T.

Mol Cell Biol. 2011 Feb;31(4):845-60. doi: 10.1128/MCB.00159-10. Epub 2010 Dec 13.


Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture.

Thomas T, Dixon MP, Kueh AJ, Voss AK.

Mol Cell Biol. 2008 Aug;28(16):5093-105. doi: 10.1128/MCB.02202-07. Epub 2008 Jun 9.

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