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Items: 18

1.

Novel peptide nanoparticle-biased antagonist of CCR3 blocks eosinophil recruitment and airway hyperresponsiveness.

Grozdanovic M, Laffey KG, Abdelkarim H, Hitchinson B, Harijith A, Moon HG, Park GY, Rousslang LK, Masterson JC, Furuta GT, Tarasova NI, Gaponenko V, Ackerman SJ.

J Allergy Clin Immunol. 2018 May 17. pii: S0091-6749(18)30709-7. doi: 10.1016/j.jaci.2018.05.003. [Epub ahead of print]

PMID:
29778505
2.

Nuclear lipid mediators: Role of nuclear sphingolipids and sphingosine-1-phosphate signaling in epigenetic regulation of inflammation and gene expression.

Fu P, Ebenezer DL, Ha AW, Suryadevara V, Harijith A, Natarajan V.

J Cell Biochem. 2018 Aug;119(8):6337-6353. doi: 10.1002/jcb.26707. Epub 2018 May 8.

PMID:
29377310
3.

Sphingolipids in Ventilator Induced Lung Injury: Role of Sphingosine-1-Phosphate Lyase.

Suryadevara V, Fu P, Ebenezer DL, Berdyshev E, Bronova IA, Huang LS, Harijith A, Natarajan V.

Int J Mol Sci. 2018 Jan 1;19(1). pii: E114. doi: 10.3390/ijms19010114.

4.

The Role of Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Lung Architecture Remodeling.

Harijith A, Natarajan V, Fu P.

Antioxidants (Basel). 2017 Dec 19;6(4). pii: E104. doi: 10.3390/antiox6040104. Review.

5.

Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia.

Natarajan V, Ha AW, Dong Y, Reddy NM, Ebenezer DL, Kanteti P, Reddy SP, Usha Raj J, Lei Z, Maienschein-Cline M, Arbieva Z, Harijith A.

BMC Genomics. 2017 Aug 29;18(1):664. doi: 10.1186/s12864-017-4048-0.

6.

Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium.

Fu P, Ebenezer DL, Berdyshev EV, Bronova IA, Shaaya M, Harijith A, Natarajan V.

J Biol Chem. 2016 Dec 30;291(53):27187-27203. doi: 10.1074/jbc.M116.758946. Epub 2016 Nov 18.

7.

Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.

Harijith A, Pendyala S, Ebenezer DL, Ha AW, Fu P, Wang YT, Ma K, Toth PT, Berdyshev EV, Kanteti P, Natarajan V.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L337-51. doi: 10.1152/ajplung.00447.2015. Epub 2016 Jun 24.

8.

Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy.

Huang LS, Berdyshev EV, Tran JT, Xie L, Chen J, Ebenezer DL, Mathew B, Gorshkova I, Zhang W, Reddy SP, Harijith A, Wang G, Feghali-Bostwick C, Noth I, Ma SF, Zhou T, Ma W, Garcia JG, Natarajan V.

Thorax. 2015 Dec;70(12):1138-48. doi: 10.1136/thoraxjnl-2014-206684. Epub 2015 Aug 18.

9.

c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury.

Fu P, Usatyuk PV, Lele A, Harijith A, Gregorio CC, Garcia JG, Salgia R, Natarajan V.

Am J Physiol Lung Cell Mol Physiol. 2015 May 15;308(10):L1025-38. doi: 10.1152/ajplung.00306.2014. Epub 2015 Mar 20.

10.

Reactive oxygen species at the crossroads of inflammasome and inflammation.

Harijith A, Ebenezer DL, Natarajan V.

Front Physiol. 2014 Sep 29;5:352. doi: 10.3389/fphys.2014.00352. eCollection 2014. Review.

11.

The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis.

Huang LS, Mathew B, Li H, Zhao Y, Ma SF, Noth I, Reddy SP, Harijith A, Usatyuk PV, Berdyshev EV, Kaminski N, Zhou T, Zhang W, Zhang Y, Rehman J, Kotha SR, Gurney TO, Parinandi NL, Lussier YA, Garcia JG, Natarajan V.

Am J Respir Crit Care Med. 2014 Jun 1;189(11):1402-15. doi: 10.1164/rccm.201310-1917OC.

12.

Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins.

Harijith A, Pendyala S, Reddy NM, Bai T, Usatyuk PV, Berdyshev E, Gorshkova I, Huang LS, Mohan V, Garzon S, Kanteti P, Reddy SP, Raj JU, Natarajan V.

Am J Pathol. 2013 Oct;183(4):1169-1182. doi: 10.1016/j.ajpath.2013.06.018. Epub 2013 Aug 8.

13.

Lysophosphatidic acid receptor-2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice.

Huang LS, Fu P, Patel P, Harijith A, Sun T, Zhao Y, Garcia JG, Chun J, Natarajan V.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):912-22. doi: 10.1165/rcmb.2013-0070OC.

14.

Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction.

Usatyuk PV, Burns M, Mohan V, Pendyala S, He D, Ebenezer DL, Harijith A, Fu P, Huang LS, Bear JE, Garcia JG, Natarajan V.

PLoS One. 2013 May 8;8(5):e63007. doi: 10.1371/journal.pone.0063007. Print 2013.

15.

Hyperoxia and interferon-γ-induced injury in developing lungs occur via cyclooxygenase-2 and the endoplasmic reticulum stress-dependent pathway.

Choo-Wing R, Syed MA, Harijith A, Bowen B, Pryhuber G, Janér C, Andersson S, Homer RJ, Bhandari V.

Am J Respir Cell Mol Biol. 2013 Jun;48(6):749-57. doi: 10.1165/rcmb.2012-0381OC.

16.

Increased hyperoxia-induced lung injury in nitric oxide synthase 2 null mice is mediated via angiopoietin 2.

Bhandari V, Choo-Wing R, Harijith A, Sun H, Syed MA, Homer RJ, Elias JA.

Am J Respir Cell Mol Biol. 2012 May;46(5):668-76. doi: 10.1165/rcmb.2011-0074OC. Epub 2012 Jan 6.

17.

A role for matrix metalloproteinase 9 in IFNγ-mediated injury in developing lungs: relevance to bronchopulmonary dysplasia.

Harijith A, Choo-Wing R, Cataltepe S, Yasumatsu R, Aghai ZH, Janér J, Andersson S, Homer RJ, Bhandari V.

Am J Respir Cell Mol Biol. 2011 May;44(5):621-30. doi: 10.1165/rcmb.2010-0058OC. Epub 2011 Jan 7.

18.

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