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Items: 1 to 20 of 32

1.

Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation.

Kumar D, Lee B, Puan KJ, Lee W, Luis BS, Yusof N, Andiappan AK, Del Rosario R, Poschmann J, Kumar P, DeLibero G, Singhal A, Prabhakar S, De Yun W, Poidinger M, Rötzschke O.

Sci Rep. 2019 Oct 23;9(1):15245. doi: 10.1038/s41598-019-51592-0.

2.

RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications.

Tan KS, Andiappan AK, Lee B, Yan Y, Liu J, Tang SA, Lum J, He TT, Ong YK, Thong M, Lim HF, Choi HW, Rotzschke O, Chow VT, Wang Y.

Cells. 2019 Aug 27;8(9). pii: E986. doi: 10.3390/cells8090986.

3.

Microarray Assay Reveals Ciliary Abnormalities of the Allergic Nasal Mucosa.

Peng Y, Guan WJ, Zhu ZC, Tan KS, Chen Z, Hong HY, Zi XX, Andiappan AK, Shi L, Yang QT, Wang DY, Qiu QH.

Am J Rhinol Allergy. 2020 Jan;34(1):50-58. doi: 10.1177/1945892419871795. Epub 2019 Aug 26. No abstract available.

PMID:
31450948
4.

Whole-transcriptome sequencing reveals heightened inflammation and defective host defence responses in chronic rhinosinusitis with nasal polyps.

Peng Y, Zi XX, Tian TF, Lee B, Lum J, Tang SA, Tan KS, Qiu QH, Ye J, Shi L, Guan WJ, Andiappan AK, Wang Y.

Eur Respir J. 2019 Nov 14;54(5). pii: 1900732. doi: 10.1183/13993003.00732-2019. Print 2019 Nov.

PMID:
31439685
5.

Different phenotypes and factors associated with atopic dermatitis in the young adult Singaporean Chinese population: A cross-sectional study.

Matta SA, Blanchet-Rethore S, Sio YY, Suri BK, Andiappan AK, Anantharaman R, Piketty C, Bourdes V, Chew FT.

World Allergy Organ J. 2019 Jan 26;12(1):100008. doi: 10.1016/j.waojou.2018.11.006. eCollection 2019.

6.

Biomarker Signatures Predicting 10-Year All-Cause and Disease-Specific Mortality.

Lu Y, Monaco G, Camous X, Andiappan AK, Rotzschke O, Ng TP, Larbi A.

J Gerontol A Biol Sci Med Sci. 2019 Mar 14;74(4):469-479. doi: 10.1093/gerona/gly138.

PMID:
30084875
7.

Genome-Wide Analysis of Protein-Coding Variants in Leprosy.

Liu H, Wang Z, Li Y, Yu G, Fu X, Wang C, Liu W, Yu Y, Bao F, Irwanto A, Liu J, Chu T, Andiappan AK, Maurer-Stroh S, Limviphuvadh V, Wang H, Mi Z, Sun Y, Sun L, Wang L, Wang C, You J, Li J, Foo JN, Liany H, Meah WY, Niu G, Yue Z, Zhao Q, Wang N, Yu M, Yu W, Cheng X, Khor CC, Sim KS, Aung T, Wang N, Wang D, Shi L, Ning Y, Zheng Z, Yang R, Li J, Yang J, Yan L, Shen J, Zhang G, Chen S, Liu J, Zhang F.

J Invest Dermatol. 2017 Dec;137(12):2544-2551. doi: 10.1016/j.jid.2017.08.004. Epub 2017 Aug 24.

8.

Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease.

Obeidat M, Nie Y, Chen V, Shannon CP, Andiappan AK, Lee B, Rotzschke O, Castaldi PJ, Hersh CP, Fishbane N, Ng RT, McManus B, Miller BE, Rennard S, Paré PD, Sin DD.

Respir Res. 2017 Apr 24;18(1):72. doi: 10.1186/s12931-017-0558-1.

9.

A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus.

Kumar D, Puan KJ, Andiappan AK, Lee B, Westerlaken GH, Haase D, Melchiotti R, Li Z, Yusof N, Lum J, Koh G, Foo S, Yeong J, Alves AC, Pekkanen J, Sun LD, Irwanto A, Fairfax BP, Naranbhai V, Common JE, Tang M, Chuang CK, Jarvelin MR, Knight JC, Zhang X, Chew FT, Prabhakar S, Jianjun L, Wang Y, Zolezzi F, Poidinger M, Lane EB, Meyaard L, Rötzschke O.

Genome Med. 2017 Feb 20;9(1):18. doi: 10.1186/s13073-017-0404-6.

10.

Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.

Sun Y, Irwanto A, Toyo-Oka L, Hong M, Liu H, Andiappan AK, Choi H, Hitomi Y, Yu G, Yu Y, Bao F, Wang C, Fu X, Yue Z, Wang H, Zhang H, Kawashima M, Kojima K, Nagasaki M, Nakamura M, Yang SK, Ye BD, Denise Y, Rotzschke O, Song K, Tokunaga K, Zhang F, Liu J.

Sci Rep. 2016 Aug 10;6:31429. doi: 10.1038/srep31429.

11.

Neuropeptide Y associated with asthma in young adults.

Lu Y, Andiappan AK, Lee B, Ho R, Lim TK, Kuan WS, Goh DY, Mahadevan M, Sim TB, Wang Y, Van Bever HP, Rotzschke O, Larbi A, Ng TP.

Neuropeptides. 2016 Oct;59:117-121. doi: 10.1016/j.npep.2016.07.003. Epub 2016 Jul 20.

PMID:
27469060
12.

Systematic characterization of basophil anergy.

Puan KJ, Andiappan AK, Lee B, Kumar D, Lai TS, Yeo G, Bercin D, Starke M, Haase D, Lum J, Chew FT, Connolly J, Wong SC, Zolezzi F, Poidinger M, Wang Y, Rötzschke O.

Allergy. 2017 Mar;72(3):373-384. doi: 10.1111/all.12952. Epub 2016 Aug 8.

PMID:
27271846
13.

Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis.

Andiappan AK, Sio YY, Lee B, Suri BK, Matta SA, Lum J, Foo S, Koh G, Liu J, Zolezzi F, Poidinger M, Wang de Y, Rotzschke O, Chew FT.

J Allergy Clin Immunol. 2016 Mar;137(3):758-66.e3. doi: 10.1016/j.jaci.2015.08.038. Epub 2015 Oct 23.

PMID:
26483175
14.

Genome-wide analysis of the genetic regulation of gene expression in human neutrophils.

Andiappan AK, Melchiotti R, Poh TY, Nah M, Puan KJ, Vigano E, Haase D, Yusof N, San Luis B, Lum J, Kumar D, Foo S, Zhuang L, Vasudev A, Irwanto A, Lee B, Nardin A, Liu H, Zhang F, Connolly J, Liu J, Mortellaro A, Wang Y, Poidinger M, Larbi A, Zolezzi F, Rotzschke O.

Nat Commun. 2015 Aug 10;6:7971. doi: 10.1038/ncomms8971.

15.

Cell Specific eQTL Analysis without Sorting Cells.

Westra HJ, Arends D, Esko T, Peters MJ, Schurmann C, Schramm K, Kettunen J, Yaghootkar H, Fairfax BP, Andiappan AK, Li Y, Fu J, Karjalainen J, Platteel M, Visschedijk M, Weersma RK, Kasela S, Milani L, Tserel L, Peterson P, Reinmaa E, Hofman A, Uitterlinden AG, Rivadeneira F, Homuth G, Petersmann A, Lorbeer R, Prokisch H, Meitinger T, Herder C, Roden M, Grallert H, Ripatti S, Perola M, Wood AR, Melzer D, Ferrucci L, Singleton AB, Hernandez DG, Knight JC, Melchiotti R, Lee B, Poidinger M, Zolezzi F, Larbi A, Wang de Y, van den Berg LH, Veldink JH, Rotzschke O, Makino S, Salomaa V, Strauch K, Völker U, van Meurs JB, Metspalu A, Wijmenga C, Jansen RC, Franke L.

PLoS Genet. 2015 May 8;11(5):e1005223. doi: 10.1371/journal.pgen.1005223. eCollection 2015 May.

16.

Evaluation of the applicability of the Immuno-solid-phase allergen chip (ISAC) assay in atopic patients in Singapore.

Santosa A, Andiappan AK, Rotzschke O, Wong HC, Chang A, Bigliardi-Qi M, Wang DY, Bigliardi PL.

Clin Transl Allergy. 2015 Feb 27;5:9. doi: 10.1186/s13601-015-0053-z. eCollection 2015.

17.

A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis.

Jin P, Andiappan AK, Quek JM, Lee B, Au B, Sio YY, Irwanto A, Schurmann C, Grabe HJ, Suri BK, Matta SA, Westra HJ, Franke L, Esko T, Sun L, Zhang X, Liu H, Zhang F, Larbi A, Xu X, Poidinger M, Liu J, Chew FT, Rotzschke O, Shi L, Wang de Y.

J Allergy Clin Immunol. 2015 Jun;135(6):1486-93.e8. doi: 10.1016/j.jaci.2014.12.1870. Epub 2015 Jan 30.

PMID:
25649076
18.

Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.

Liu H, Irwanto A, Fu X, Yu G, Yu Y, Sun Y, Wang C, Wang Z, Okada Y, Low H, Li Y, Liany H, Chen M, Bao F, Li J, You J, Zhang Q, Liu J, Chu T, Andiappan AK, Wang N, Niu G, Liu D, Yu X, Zhang L, Tian H, Zhou G, Rotzschke O, Chen S, Zhang X, Liu J, Zhang F.

Nat Genet. 2015 Mar;47(3):267-71. doi: 10.1038/ng.3212. Epub 2015 Feb 2.

PMID:
25642632
19.

Genetic variants of inducible costimulator are associated with allergic asthma susceptibility.

Andiappan AK, Narayanan S, Myers RA, Lee B, Nieuwenhuis MA, Nardin A, Park CS, Shin HD, Kim JH, Westra HJ, Franke L, Esko T, Metspalu A, Teo YY, Saw SM, Khor CC, Liu J, Koppelman GH, Postma DS, Poidinger M, Connolly JE, Wang de Y, Rotzschke O, Curotto de Lafaille MA, Chew FT.

J Allergy Clin Immunol. 2015 Feb;135(2):556-8. doi: 10.1016/j.jaci.2014.06.028. Epub 2014 Aug 7. No abstract available.

PMID:
25109803
20.

γ/δ T cell subsets in human aging using the classical α/β T cell model.

Vasudev A, Ying CT, Ayyadhury S, Puan KJ, Andiappan AK, Nyunt MS, Shadan NB, Mustafa S, Low I, Rotzschke O, Fulop T, Ng TP, Larbi A.

J Leukoc Biol. 2014 Oct;96(4):647-55. doi: 10.1189/jlb.5A1213-650RR. Epub 2014 Jul 7.

PMID:
25001861

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