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Items: 14

1.

Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair.

López-Iglesias AA, Herrero AB, Chesi M, San-Segundo L, González-Méndez L, Hernández-García S, Misiewicz-Krzeminska I, Quwaider D, Martín-Sánchez M, Primo D, Paíno T, Bergsagel PL, Mehrling T, González-Díaz M, San-Miguel JF, Mateos MV, Gutiérrez NC, Garayoa M, Ocio EM.

J Hematol Oncol. 2017 Jun 20;10(1):127. doi: 10.1186/s13045-017-0495-y.

2.

DEPTOR maintains plasma cell differentiation and favorably affects prognosis in multiple myeloma.

Quwaider D, Corchete LA, Misiewicz-Krzeminska I, Sarasquete ME, Pérez JJ, Krzeminski P, Puig N, Mateos MV, García-Sanz R, Herrero AB, Gutiérrez NC.

J Hematol Oncol. 2017 Apr 18;10(1):92. doi: 10.1186/s13045-017-0461-8.

3.

Molecular Mechanisms of p53 Deregulation in Cancer: An Overview in Multiple Myeloma.

Herrero AB, Rojas EA, Misiewicz-Krzeminska I, Krzeminski P, Gutiérrez NC.

Int J Mol Sci. 2016 Nov 30;17(12). pii: E2003. Review.

4.

Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bortezomib and dexamethasone.

López-Iglesias AA, González-Méndez L, San-Segundo L, Herrero AB, Hernández-García S, Martín-Sánchez M, Gutiérrez NC, Paíno T, Avilés P, Mateos MV, San-Miguel JF, Garayoa M, Ocio EM.

Haematologica. 2017 Jan;102(1):168-175. doi: 10.3324/haematol.2016.146076. Epub 2016 Aug 18.

5.

Effects of IL-8 Up-Regulation on Cell Survival and Osteoclastogenesis in Multiple Myeloma.

Herrero AB, García-Gómez A, Garayoa M, Corchete LA, Hernández JM, San Miguel J, Gutierrez NC.

Am J Pathol. 2016 Aug;186(8):2171-82. doi: 10.1016/j.ajpath.2016.04.003. Epub 2016 Jun 11.

PMID:
27301357
6.

Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair.

Castaño J, Herrero AB, Bursen A, González F, Marschalek R, Gutiérrez NC, Menendez P.

Oncotarget. 2016 May 24;7(21):30440-52. doi: 10.18632/oncotarget.8938.

7.

Deregulation of DNA double-strand break repair in multiple myeloma: implications for genome stability.

Herrero AB, San Miguel J, Gutierrez NC.

PLoS One. 2015 Mar 19;10(3):e0121581. doi: 10.1371/journal.pone.0121581. eCollection 2015.

8.

Npl3, a new link between RNA-binding proteins and the maintenance of genome integrity.

Santos-Pereira JM, Herrero AB, Moreno S, Aguilera A.

Cell Cycle. 2014;13(10):1524-9. doi: 10.4161/cc.28708. Epub 2014 Apr 2.

9.

The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability.

Santos-Pereira JM, Herrero AB, García-Rubio ML, Marín A, Moreno S, Aguilera A.

Genes Dev. 2013 Nov 15;27(22):2445-58. doi: 10.1101/gad.229880.113.

10.

Lsm1 promotes genomic stability by controlling histone mRNA decay.

Herrero AB, Moreno S.

EMBO J. 2011 May 18;30(10):2008-18. doi: 10.1038/emboj.2011.117. Epub 2011 Apr 12.

11.

Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734.

Herrero AB, Astudillo AM, Balboa MA, Cuevas C, Balsinde J, Moreno S.

Cancer Res. 2008 Dec 1;68(23):9779-87. doi: 10.1158/0008-5472.CAN-08-1981.

12.

Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedin.

Herrero AB, Martín-Castellanos C, Marco E, Gago F, Moreno S.

Cancer Res. 2006 Aug 15;66(16):8155-62.

13.

KRE5 gene null mutant strains of Candida albicans are avirulent and have altered cell wall composition and hypha formation properties.

Herrero AB, Magnelli P, Mansour MK, Levitz SM, Bussey H, Abeijon C.

Eukaryot Cell. 2004 Dec;3(6):1423-32.

14.

The Golgi GDPase of the fungal pathogen Candida albicans affects morphogenesis, glycosylation, and cell wall properties.

Herrero AB, Uccelletti D, Hirschberg CB, Dominguez A, Abeijon C.

Eukaryot Cell. 2002 Jun;1(3):420-31.

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