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Items: 1 to 20 of 78

1.

Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilization.

Kuwana T, King LE, Cosentino K, Suess J, Garcia-Saez AJ, Gilmore AP, Newmeyer DD.

J Biol Chem. 2020 Feb 7;295(6):1623-1636. doi: 10.1074/jbc.RA119.011635. Epub 2020 Jan 3.

PMID:
31901077
2.

MERLIN: a novel BRET-based proximity biosensor for studying mitochondria-ER contact sites.

Hertlein V, Flores-Romero H, Das KK, Fischer S, Heunemann M, Calleja-Felipe M, Knafo S, Hipp K, Harter K, Fitzgerald JC, García-Sáez AJ.

Life Sci Alliance. 2019 Dec 9;3(1). pii: e201900600. doi: 10.26508/lsa.201900600. Print 2020 Jan.

3.

The Incomplete Puzzle of the BCL2 Proteins.

Flores-Romero H, García-Sáez AJ.

Cells. 2019 Sep 29;8(10). pii: E1176. doi: 10.3390/cells8101176.

4.

A new perspective on membrane-embedded Bax oligomers using DEER and bioresistant orthogonal spin labels.

Teucher M, Zhang H, Bader V, Winklhofer KF, García-Sáez AJ, Rajca A, Bleicken S, Bordignon E.

Sci Rep. 2019 Sep 10;9(1):13013. doi: 10.1038/s41598-019-49370-z.

5.

Quantitative analysis of super-resolved structures using ASAP.

Danial JSH, Garcia-Saez AJ.

Nat Methods. 2019 Aug;16(8):711-714. doi: 10.1038/s41592-019-0472-1. Epub 2019 Jul 1.

6.

Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim.

Singh PK, Roukounakis A, Weber A, Das KK, Sohm B, Villunger A, Garcia-Saez AJ, Häcker G.

Cell Death Differ. 2020 Feb;27(2):434-450. doi: 10.1038/s41418-019-0365-y. Epub 2019 Jun 12.

PMID:
31189926
7.

MAVS-induced mitochondrial membrane remodeling.

Flores-Romero H, García-Sáez AJ.

FEBS J. 2019 Apr;286(8):1540-1542. doi: 10.1111/febs.14822. Epub 2019 Apr 8.

PMID:
30957952
8.

BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL.

Flores-Romero H, Landeta O, Ugarte-Uribe B, Cosentino K, García-Porras M, García-Sáez AJ, Basañez G.

Cell Death Differ. 2019 Oct;26(10):1880-1894. doi: 10.1038/s41418-018-0258-5. Epub 2018 Dec 18.

9.

Quantification of the Interactions Between BCL-2 Proteins by Fluorescence Correlation Spectroscopy.

Murad F, Garcia-Saez AJ.

Methods Mol Biol. 2019;1877:337-350. doi: 10.1007/978-1-4939-8861-7_20.

PMID:
30536014
10.

Single event visualization of unconventional secretion of FGF2.

Dimou E, Cosentino K, Platonova E, Ros U, Sadeghi M, Kashyap P, Katsinelos T, Wegehingel S, Noé F, García-Sáez AJ, Ewers H, Nickel W.

J Cell Biol. 2019 Feb 4;218(2):683-699. doi: 10.1083/jcb.201802008. Epub 2018 Nov 23.

11.

AFM to Study Pore-Forming Proteins.

Unsay JD, García-Sáez AJ.

Methods Mol Biol. 2019;1886:191-202. doi: 10.1007/978-1-4939-8894-5_10.

PMID:
30374868
12.

Scanning Fluorescence Correlation Spectroscopy for Quantification of the Dynamics and Interactions in Tube Organelles of Living Cells.

Unsay JD, Murad F, Hermann E, Ries J, García-Sáez AJ.

Chemphyschem. 2018 Oct 18. doi: 10.1002/cphc.201800705. [Epub ahead of print]

PMID:
30335213
13.

Topology of active, membrane-embedded Bax in the context of a toroidal pore.

Bleicken S, Assafa TE, Stegmueller C, Wittig A, Garcia-Saez AJ, Bordignon E.

Cell Death Differ. 2018 Nov;25(10):1717-1731. doi: 10.1038/s41418-018-0184-6. Epub 2018 Sep 5.

14.

MIM through MOM: the awakening of Bax and Bak pores.

Cosentino K, García-Sáez AJ.

EMBO J. 2018 Sep 3;37(17). pii: e100340. doi: 10.15252/embj.2018100340. Epub 2018 Aug 22. No abstract available.

15.

Early activation of CD95 is limited and localized to the cytotoxic synapse.

Sánchez MF, Murad F, Gülcüler Balta GS, Martin-Villalba A, García-Sáez AJ, Carrer DC.

FEBS J. 2018 Aug;285(15):2813-2827. doi: 10.1111/febs.14518. Epub 2018 Jun 19.

16.

Bax retrotranslocation potentiates Bcl-xL's antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance.

Hantusch A, Das KK, García-Sáez AJ, Brunner T, Rehm M.

Cell Death Dis. 2018 Apr 1;9(4):430. doi: 10.1038/s41419-018-0464-6.

17.

The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane.

Böhler P, Stuhldreier F, Anand R, Kondadi AK, Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Wu W, Frank M, Niemann H, Wesbuer E, Barbian A, Luyten T, Parys JB, Weidtkamp-Peters S, Borchardt A, Reichert AS, Peña-Blanco A, García-Sáez AJ, Itskanov S, van der Bliek AM, Proksch P, Wesselborg S, Stork B.

Cell Death Dis. 2018 Feb 19;9(3):286. doi: 10.1038/s41419-018-0312-8.

18.

Bcl-2 proteins: Unraveling the details of a complex and dynamic network.

Bleicken S, Garcia-Saez AJ.

Mol Cell Oncol. 2017 Oct 30;5(1):e1384880. doi: 10.1080/23723556.2017.1384880. eCollection 2018.

19.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

20.

Drp1 polymerization stabilizes curved tubular membranes similar to those of constricted mitochondria.

Ugarte-Uribe B, Prévost C, Das KK, Bassereau P, García-Sáez AJ.

J Cell Sci. 2018 Apr 19;132(4). pii: jcs208603. doi: 10.1242/jcs.208603.

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