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Items: 12


Improved Aptamers for the Diagnosis and Potential Treatment of HER2-Positive Cancer.

Gijs M, Penner G, Blackler GB, Impens NR, Baatout S, Luxen A, Aerts AM.

Pharmaceuticals (Basel). 2016 May 19;9(2). pii: E29. doi: 10.3390/ph9020029.


The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans.

Aerts AM, Bammens L, Govaert G, Carmona-Gutierrez D, Madeo F, Cammue BP, Thevissen K.

Front Microbiol. 2011 Mar 16;2:47. doi: 10.3389/fmicb.2011.00047. eCollection 2011.


Skn1 and Ipt1 negatively regulate autophagy in Saccharomyces cerevisiae.

Thevissen K, Yen WL, Carmona-Gutierrez D, Idkowiak-Baldys J, Aerts AM, François IE, Madeo F, Klionsky DJ, Hannun YA, Cammue BP.

FEMS Microbiol Lett. 2010 Feb;303(2):163-8. doi: 10.1111/j.1574-6968.2009.01869.x. Epub 2009 Nov 27.


The antifungal plant defensin RsAFP2 from radish induces apoptosis in a metacaspase independent way in Candida albicans.

Aerts AM, Carmona-Gutierrez D, Lefevre S, Govaert G, François IE, Madeo F, Santos R, Cammue BP, Thevissen K.

FEBS Lett. 2009 Aug 6;583(15):2513-6. doi: 10.1016/j.febslet.2009.07.004. Epub 2009 Jul 14.


Mitochondrial dysfunction leads to reduced chronological lifespan and increased apoptosis in yeast.

Aerts AM, Zabrocki P, Govaert G, Mathys J, Carmona-Gutierrez D, Madeo F, Winderickx J, Cammue BP, Thevissen K.

FEBS Lett. 2009 Jan 5;583(1):113-7. doi: 10.1016/j.febslet.2008.11.028. Epub 2008 Dec 4.


The antifungal activity of RsAFP2, a plant defensin from raphanus sativus, involves the induction of reactive oxygen species in Candida albicans.

Aerts AM, François IE, Meert EM, Li QT, Cammue BP, Thevissen K.

J Mol Microbiol Biotechnol. 2007;13(4):243-7.


Miconazole induces changes in actin cytoskeleton prior to reactive oxygen species induction in yeast.

Thevissen K, Ayscough KR, Aerts AM, Du W, De Brucker K, Meert EM, Ausma J, Borgers M, Cammue BP, François IE.

J Biol Chem. 2007 Jul 27;282(30):21592-7. Epub 2007 Jun 6.


Arabidopsis thaliana plants expressing human beta-defensin-2 are more resistant to fungal attack: functional homology between plant and human defensins.

Aerts AM, Thevissen K, Bresseleers SM, Sels J, Wouters P, Cammue BP, François IE.

Plant Cell Rep. 2007 Aug;26(8):1391-8. Epub 2007 Mar 6.


Use of a PTGS-MAR expression system for efficient in planta production of bioactive Arabidopsis thaliana plant defensins.

Sels J, Delauré SL, Aerts AM, Proost P, Cammue BP, De Bolle MF.

Transgenic Res. 2007 Aug;16(4):531-8. Epub 2006 Dec 19.


Level of M(IP)2C sphingolipid affects plant defensin sensitivity, oxidative stress resistance and chronological life-span in yeast.

Aerts AM, François IE, Bammens L, Cammue BP, Smets B, Winderickx J, Accardo S, De Vos DE, Thevissen K.

FEBS Lett. 2006 Mar 20;580(7):1903-7. Epub 2006 Mar 3.


Currently used antimycotics: spectrum, mode of action and resistance occurrence.

Francois IE, Aerts AM, Cammue BP, Thevissen K.

Curr Drug Targets. 2005 Dec;6(8):895-907. Review.


SKN1, a novel plant defensin-sensitivity gene in Saccharomyces cerevisiae, is implicated in sphingolipid biosynthesis.

Thevissen K, Idkowiak-Baldys J, Im YJ, Takemoto J, François IE, Ferket KK, Aerts AM, Meert EM, Winderickx J, Roosen J, Cammue BP.

FEBS Lett. 2005 Mar 28;579(9):1973-7.

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