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Items: 1 to 20 of 61


Pharmacokinetic and Metabolomic Studies with BIO 300, a Nanosuspension of Genistein, in a Nonhuman Primate Model.

Cheema AK, Mehta KY, Santiago PT, Fatanmi OO, Kaytor MD, Singh VK.

Int J Mol Sci. 2019 Mar 12;20(5). pii: E1231. doi: 10.3390/ijms20051231.


Plasma Derived Exosomal Biomarkers of Exposure to Ionizing Radiation in Nonhuman Primates.

Cheema AK, Hinzman CP, Mehta KY, Hanlon BK, Garcia M, Fatanmi OO, Singh VK.

Int J Mol Sci. 2018 Nov 1;19(11). pii: E3427. doi: 10.3390/ijms19113427.


Poisoning with Soman, an Organophosphorus Nerve Agent, Alters Fecal Bacterial Biota and Urine Metabolites: a Case for Novel Signatures for Asymptomatic Nerve Agent Exposure.

Getnet D, Gautam A, Kumar R, Hoke A, Cheema AK, Rossetti F, Schultz CR, Hammamieh R, Lumley LA, Jett M.

Appl Environ Microbiol. 2018 Oct 17;84(21). pii: e00978-18. doi: 10.1128/AEM.00978-18. Print 2018 Nov 1.


Potential Metabolomic Linkage in Blood between Parkinson's Disease and Traumatic Brain Injury.

Fiandaca MS, Gross TJ, Johnson TM, Hu MT, Evetts S, Wade-Martins R, Merchant-Borna K, Bazarian J, Cheema AK, Mapstone M, Federoff HJ.

Metabolites. 2018 Sep 7;8(3). pii: E50. doi: 10.3390/metabo8030050.


Plasma microRNA markers of upper limb recovery following human stroke.

Edwardson MA, Zhong X, Fiandaca MS, Federoff HJ, Cheema AK, Dromerick AW.

Sci Rep. 2018 Aug 22;8(1):12558. doi: 10.1038/s41598-018-31020-5.


Exposure to Ionizing Radiation Causes Endoplasmic Reticulum Stress in the Mouse Hippocampus.

Hinzman CP, Baulch JE, Mehta KY, Gill K, Limoli CL, Cheema AK.

Radiat Res. 2018 Nov;190(5):483-493. doi: 10.1667/RR15061.1. Epub 2018 Aug 7.


Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol.

Cheema AK, Byrum SD, Sharma NK, Altadill T, Kumar VP, Biswas S, Balgley BM, Hauer-Jensen M, Tackett AJ, Ghosh SP.

Radiat Res. 2018 Nov;190(5):449-463. doi: 10.1667/RR15008.1. Epub 2018 Aug 2.


Toward Reproducible Results from Targeted Metabolomic Studies: Perspectives for Data Pre-processing and a Basis for Analytic Pipeline Development.

Gross T, Mapstone M, Miramontes R, Padilla R, Cheema AK, Macciardi F, Federoff HJ, Fiandaca MS.

Curr Top Med Chem. 2018;18(11):883-895. doi: 10.2174/1568026618666180711144323. Review.


Metabolomics based predictive classifier for early detection of pancreatic ductal adenocarcinoma.

Unger K, Mehta KY, Kaur P, Wang Y, Menon SS, Jain SK, Moonjelly RA, Suman S, Datta K, Singh R, Fogel P, Cheema AK.

Oncotarget. 2018 May 1;9(33):23078-23090. doi: 10.18632/oncotarget.25212. eCollection 2018 May 1.


Plasma metabolomic biomarkers accurately classify acute mild traumatic brain injury from controls.

Fiandaca MS, Mapstone M, Mahmoodi A, Gross T, Macciardi F, Cheema AK, Merchant-Borna K, Bazarian J, Federoff HJ.

PLoS One. 2018 Apr 20;13(4):e0195318. doi: 10.1371/journal.pone.0195318. eCollection 2018.


A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies.

Deeken JF, Wang H, Hartley M, Cheema AK, Smaglo B, Hwang JJ, He AR, Weiner LM, Marshall JL, Giaccone G, Liu S, Luecht J, Spiegel JY, Pishvaian MJ.

Cancer Chemother Pharmacol. 2018 Mar;81(3):587-596. doi: 10.1007/s00280-018-3533-8. Epub 2018 Feb 1.


A Metabolomic and Lipidomic Serum Signature from Nonhuman Primates Administered with a Promising Radiation Countermeasure, Gamma-Tocotrienol.

Cheema AK, Mehta KY, Fatanmi OO, Wise SY, Hinzman CP, Wolff J, Singh VK.

Int J Mol Sci. 2017 Dec 28;19(1). pii: E79. doi: 10.3390/ijms19010079.


EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer.

Shajahan-Haq AN, Boca SM, Jin L, Bhuvaneshwar K, Gusev Y, Cheema AK, Demas DD, Raghavan KS, Michalek R, Madhavan S, Clarke R.

Oncotarget. 2017 May 30;8(57):96865-96884. doi: 10.18632/oncotarget.18292. eCollection 2017 Nov 14.


Metabolomic biomarkers of pancreatic cancer: a meta-analysis study.

Mehta KY, Wu HJ, Menon SS, Fallah Y, Zhong X, Rizk N, Unger K, Mapstone M, Fiandaca MS, Federoff HJ, Cheema AK.

Oncotarget. 2017 Aug 18;8(40):68899-68915. doi: 10.18632/oncotarget.20324. eCollection 2017 Sep 15.


Metabolomic and Lipidomic Profiling Identifies The Role of the RNA Editing Pathway in Endometrial Carcinogenesis.

Altadill T, Dowdy TM, Gill K, Reques A, Menon SS, Moiola CP, Lopez-Gil C, Coll E, Matias-Guiu X, Cabrera S, Garcia A, Reventos J, Byers SW, Gil-Moreno A, Cheema AK, Colas E.

Sci Rep. 2017 Aug 18;7(1):8803. doi: 10.1038/s41598-017-09169-2.


Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome.

Casero D, Gill K, Sridharan V, Koturbash I, Nelson G, Hauer-Jensen M, Boerma M, Braun J, Cheema AK.

Microbiome. 2017 Aug 18;5(1):105. doi: 10.1186/s40168-017-0325-z.


One-carbon metabolism and ionizing radiation: a multifaceted interaction.

Miousse IR, Tobacyk J, Melnyk S, James SJ, Cheema AK, Boerma M, Hauer-Jensen M, Koturbash I.

Biomol Concepts. 2017 May 24;8(2):83-92. doi: 10.1515/bmc-2017-0003. Review.


Biomarker validation: Methods and matrix matter.

Mapstone M, Cheema AK, Zhong X, Fiandaca MS, Federoff HJ.

Alzheimers Dement. 2017 May;13(5):608-609. doi: 10.1016/j.jalz.2016.11.004. Epub 2016 Dec 21. No abstract available.


What success can teach us about failure: the plasma metabolome of older adults with superior memory and lessons for Alzheimer's disease.

Mapstone M, Lin F, Nalls MA, Cheema AK, Singleton AB, Fiandaca MS, Federoff HJ.

Neurobiol Aging. 2017 Mar;51:148-155. doi: 10.1016/j.neurobiolaging.2016.11.007. Epub 2016 Nov 21.


Effects of ionizing radiation on the heart.

Boerma M, Sridharan V, Mao XW, Nelson GA, Cheema AK, Koturbash I, Singh SP, Tackett AJ, Hauer-Jensen M.

Mutat Res. 2016 Oct - Dec;770(Pt B):319-327. doi: 10.1016/j.mrrev.2016.07.003. Epub 2016 Jul 10. Review.

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