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Items: 1 to 20 of 184

1.

S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma.

Xiao Y, Zhao H, Tian L, Nolley R, Diep AN, Ernst A, Fuh KC, Miao YR, von Eyben R, Leppert JT, Brooks JD, Peehl DM, Giaccia AJ, Rankin EB.

Cancer Res. 2019 Nov 15;79(22):5758-5768. doi: 10.1158/0008-5472.CAN-19-1366. Epub 2019 Oct 4.

PMID:
31585940
2.

Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma.

Gholamin S, Youssef OA, Rafat M, Esparza R, Kahn S, Shahin M, Giaccia AJ, Graves EE, Weissman I, Mitra S, Cheshier SH.

Innate Immun. 2019 Sep 23:1753425919876690. doi: 10.1177/1753425919876690. [Epub ahead of print] No abstract available.

PMID:
31547758
3.

Lambda-Carrageenan Enhances the Effects of Radiation Therapy in Cancer Treatment by Suppressing Cancer Cell Invasion and Metastasis through Racgap1 Inhibition.

Wu PH, Onodera Y, Recuenco FC, Giaccia AJ, Le QT, Shimizu S, Shirato H, Nam JM.

Cancers (Basel). 2019 Aug 16;11(8). pii: E1192. doi: 10.3390/cancers11081192.

4.

HILPDA Regulates Lipid Metabolism, Lipid Droplet Abundance, and Response to Microenvironmental Stress in Solid Tumors.

VandeKopple MJ, Wu J, Auer EN, Giaccia AJ, Denko NC, Papandreou I.

Mol Cancer Res. 2019 Oct;17(10):2089-2101. doi: 10.1158/1541-7786.MCR-18-1343. Epub 2019 Jul 15.

PMID:
31308147
5.

Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate.

Yao Q, Khan MP, Merceron C, LaGory EL, Tata Z, Mangiavini L, Hu J, Vemulapalli K, Chandel NS, Giaccia AJ, Schipani E.

Dev Cell. 2019 Jun 3;49(5):748-763.e7. doi: 10.1016/j.devcel.2019.04.029. Epub 2019 May 16.

PMID:
31105007
6.

Wounds Inhibit Tumor Growth In Vivo.

Hu MS, Maan ZN, Leavitt T, Hong WX, Rennert RC, Marshall CD, Borrelli MR, Zhu TN, Esquivel M, Zimmermann A, McArdle A, Chung MT, Foster DS, Jones RE, Gurtner GC, Giaccia AJ, Lorenz HP, Weissman IL, Longaker MT.

Ann Surg. 2019 Feb 27. doi: 10.1097/SLA.0000000000003255. [Epub ahead of print]

PMID:
30829705
7.

Hypoxia-inducible factor 2α is a negative regulator of osteoblastogenesis and bone mass accrual.

Merceron C, Ranganathan K, Wang E, Tata Z, Makkapati S, Khan MP, Mangiavini L, Yao AQ, Castellini L, Levi B, Giaccia AJ, Schipani E.

Bone Res. 2019 Feb 21;7:7. doi: 10.1038/s41413-019-0045-z. eCollection 2019.

8.

Targeting the Tumor Microenvironment in Radiation Oncology: Proceedings from the 2018 ASTRO-AACR Research Workshop.

McGee HM, Jiang D, Soto-Pantoja DR, Nevler A, Giaccia AJ, Woodward WA.

Clin Cancer Res. 2019 May 15;25(10):2969-2974. doi: 10.1158/1078-0432.CCR-18-3781. Epub 2019 Feb 5.

PMID:
30723144
9.

Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer.

Olcina MM, Balanis NG, Kim RK, Aksoy BA, Kodysh J, Thompson MJ, Hammerbacher J, Graeber TG, Giaccia AJ.

Cell Rep. 2018 Dec 26;25(13):3721-3732.e6. doi: 10.1016/j.celrep.2018.11.093.

10.

Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature.

Jiang X, Tian W, Tu AB, Pasupneti S, Shuffle E, Dahms P, Zhang P, Cai H, Dinh TT, Liu B, Cain C, Giaccia AJ, Butcher EC, Simon MC, Semenza GL, Nicolls MR.

Circulation. 2019 Jan 22;139(4):502-517. doi: 10.1161/CIRCULATIONAHA.118.036157.

PMID:
30586708
11.

Generation of Stable Expression Mammalian Cell Lines Using Lentivirus.

Tandon N, Thakkar KN, LaGory EL, Liu Y, Giaccia AJ.

Bio Protoc. 2018 Nov 5;8(21). pii: e3073. doi: 10.21769/BioProtoc.3073.

12.

Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity.

Chen X, Litzenburger UM, Wei Y, Schep AN, LaGory EL, Choudhry H, Giaccia AJ, Greenleaf WJ, Chang HY.

Nat Commun. 2018 Nov 2;9(1):4590. doi: 10.1038/s41467-018-07115-y.

13.

Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism.

Benej M, Hong X, Vibhute S, Scott S, Wu J, Graves E, Le QT, Koong AC, Giaccia AJ, Yu B, Chen CS, Papandreou I, Denko NC.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10756-10761. doi: 10.1073/pnas.1808945115. Epub 2018 Sep 10. Erratum in: Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11561.

14.

Macrophages Promote Circulating Tumor Cell-Mediated Local Recurrence following Radiotherapy in Immunosuppressed Patients.

Rafat M, Aguilera TA, Vilalta M, Bronsart LL, Soto LA, von Eyben R, Golla MA, Ahrari Y, Melemenidis S, Afghahi A, Jenkins MJ, Kurian AW, Horst KC, Giaccia AJ, Graves EE.

Cancer Res. 2018 Aug 1;78(15):4241-4252. doi: 10.1158/0008-5472.CAN-17-3623. Epub 2018 Jun 7.

15.

The tumour microenvironment links complement system dysregulation and hypoxic signalling.

Olcina MM, Kim RK, Melemenidis S, Graves EE, Giaccia AJ.

Br J Radiol. 2018 May 15:20180069. doi: 10.1259/bjr.20180069. [Epub ahead of print]

PMID:
29544344
16.

A Human Genome-Wide RNAi Screen Reveals Diverse Modulators that Mediate IRE1α-XBP1 Activation.

Yang Z, Zhang J, Jiang D, Khatri P, Solow-Cordero DE, Toesca DAS, Koumenis C, Denko NC, Giaccia AJ, Le QT, Koong AC.

Mol Cancer Res. 2018 May;16(5):745-753. doi: 10.1158/1541-7786.MCR-17-0307. Epub 2018 Feb 9.

17.

PHD-2 Suppression in Mesenchymal Stromal Cells Enhances Wound Healing.

Ko SH, Nauta AC, Morrison SD, Hu MS, Zimmermann AS, Chung MT, Glotzbach JP, Wong VW, Walmsley GG, Peter Lorenz H, Chan DA, Gurtner GC, Giaccia AJ, Longaker MT.

Plast Reconstr Surg. 2018 Jan;141(1):55e-67e. doi: 10.1097/PRS.0000000000003959.

18.

Long-range hypoxia signaling in NAFLD.

LaGory EL, Giaccia AJ.

Nat Med. 2017 Nov 7;23(11):1251-1252. doi: 10.1038/nm.4436. No abstract available.

PMID:
29117167
19.

Targeting integrins with RGD-conjugated gold nanoparticles in radiotherapy decreases the invasive activity of breast cancer cells.

Wu PH, Onodera Y, Ichikawa Y, Rankin EB, Giaccia AJ, Watanabe Y, Qian W, Hashimoto T, Shirato H, Nam JM.

Int J Nanomedicine. 2017 Jul 14;12:5069-5085. doi: 10.2147/IJN.S137833. eCollection 2017.

20.

BLIMP1 Induces Transient Metastatic Heterogeneity in Pancreatic Cancer.

Chiou SH, Risca VI, Wang GX, Yang D, Grüner BM, Kathiria AS, Ma RK, Vaka D, Chu P, Kozak M, Castellini L, Graves EE, Kim GE, Mourrain P, Koong AC, Giaccia AJ, Winslow MM.

Cancer Discov. 2017 Oct;7(10):1184-1199. doi: 10.1158/2159-8290.CD-17-0250. Epub 2017 Aug 8.

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