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Reduced Plasma Orexin-A Concentrations are Associated with Cognitive Deficits in Anorexia Nervosa.

Steward T, Mestre-Bach G, Granero R, Sánchez I, Riesco N, Vintró-Alcaraz C, Sauchelli S, Jiménez-Murcia S, Agüera Z, Fernández-García JC, Garrido-Sánchez L, Tinahones FJ, Casanueva FF, Baños RM, Botella C, Crujeiras AB, Torre R, Fernández-Real JM, Frühbeck G, Ortega FJ, Rodríguez A, Menchón JM, Fernández-Aranda F.

Sci Rep. 2019 May 27;9(1):7910. doi: 10.1038/s41598-019-44450-6.


Associations between neuropsychological performance and appetite-regulating hormones in anorexia nervosa and healthy controls: Ghrelin's putative role as a mediator of decision-making.

Paslakis G, Agüera Z, Granero R, Sánchez I, Riesco N, Jiménez-Murcia S, Fernández-García JC, Garrido-Sánchez L, Tinahones FJ, Casanueva FF, Baños RM, Botella C, Crujeiras AB, Torre R, Fernández-Real JM, Frühbeck G, Ortega FJ, Rodríguez A, Serra-Majem L, Fitó M, Menchón JM, Fernández-Aranda F.

Mol Cell Endocrinol. 2019 May 20:110441. doi: 10.1016/j.mce.2019.04.021. [Epub ahead of print] Review.


GLP-1 Limits Adipocyte Inflammation and Its Low Circulating Pre-Operative Concentrations Predict Worse Type 2 Diabetes Remission after Bariatric Surgery in Obese Patients.

Izaguirre M, Gómez-Ambrosi J, Rodríguez A, Ramírez B, Becerril S, Valentí V, Moncada R, Unamuno X, Silva C, de la Higuera M, Salvador J, Monreal I, Frühbeck G, Catalán V.

J Clin Med. 2019 Apr 9;8(4). pii: E479. doi: 10.3390/jcm8040479.


Circulating GDF11 levels are decreased with age but are unchanged with obesity and type 2 diabetes.

Añón-Hidalgo J, Catalán V, Rodríguez A, Ramírez B, Silva C, Galofré JC, Salvador J, Frühbeck G, Gómez-Ambrosi J.

Aging (Albany NY). 2019 Mar 21;11(6):1733-1744. doi: 10.18632/aging.101865.


iNOS Gene Ablation Prevents Liver Fibrosis in Leptin-Deficient ob/ob Mice.

Becerril S, Rodríguez A, Catalán V, Ramírez B, Unamuno X, Gómez-Ambrosi J, Frühbeck G.

Genes (Basel). 2019 Feb 27;10(3). pii: E184. doi: 10.3390/genes10030184.


Adiponectin-leptin Ratio is a Functional Biomarker of Adipose Tissue Inflammation.

Frühbeck G, Catalán V, Rodríguez A, Ramírez B, Becerril S, Salvador J, Colina I, Gómez-Ambrosi J.

Nutrients. 2019 Feb 22;11(2). pii: E454. doi: 10.3390/nu11020454.


For Debate: Paediatric T1DM: DKA is Still a Problem.

Martínez E, Portillo N, Lizarralde E, Grau G, Vela A, Rodríguez A, Rica I.

Pediatr Endocrinol Rev. 2018 Dec;16(2):233-239. doi: 10.17458/per.vol16.2018.mpr.fd.t1dmdka.


The caveolae-associated coiled-coil protein, NECC2, regulates insulin signalling in Adipocytes.

Trávez A, Rabanal-Ruiz Y, López-Alcalá J, Molero-Murillo L, Díaz-Ruiz A, Guzmán-Ruiz R, Catalán V, Rodríguez A, Frühbeck G, Tinahones FJ, Gasman S, Vitale N, Jiménez-Gómez Y, Malagón MM.

J Cell Mol Med. 2018 Nov;22(11):5648-5661. doi: 10.1111/jcmm.13840. Epub 2018 Aug 30.


Ghrelin Reduces TNF-α-Induced Human Hepatocyte Apoptosis, Autophagy, and Pyroptosis: Role in Obesity-Associated NAFLD.

Ezquerro S, Mocha F, Frühbeck G, Guzmán-Ruiz R, Valentí V, Mugueta C, Becerril S, Catalán V, Gómez-Ambrosi J, Silva C, Salvador J, Colina I, Malagón MM, Rodríguez A.

J Clin Endocrinol Metab. 2019 Jan 1;104(1):21-37. doi: 10.1210/jc.2018-01171.


Adipokine dysregulation and adipose tissue inflammation in human obesity.

Unamuno X, Gómez-Ambrosi J, Rodríguez A, Becerril S, Frühbeck G, Catalán V.

Eur J Clin Invest. 2018 Sep;48(9):e12997. doi: 10.1111/eci.12997. Epub 2018 Aug 3. Review.


Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity-a pilot study.

Cheng Y, Monteiro C, Matos A, You J, Fraga A, Pereira C, Catalán V, Rodríguez A, Gómez-Ambrosi J, Frühbeck G, Ribeiro R, Hu P.

Clin Epigenetics. 2018 Apr 17;10:54. doi: 10.1186/s13148-018-0490-3. eCollection 2018.


Novel protective role of kallistatin in obesity by limiting adipose tissue low grade inflammation and oxidative stress.

Frühbeck G, Gómez-Ambrosi J, Rodríguez A, Ramírez B, Valentí V, Moncada R, Becerril S, Unamuno X, Silva C, Salvador J, Catalán V.

Metabolism. 2018 Oct;87:123-135. doi: 10.1016/j.metabol.2018.04.004. Epub 2018 Apr 18.


Pancreatic Aquaporin-7: A Novel Target for Anti-diabetic Drugs?

Méndez-Giménez L, Ezquerro S, da Silva IV, Soveral G, Frühbeck G, Rodríguez A.

Front Chem. 2018 Apr 5;6:99. doi: 10.3389/fchem.2018.00099. eCollection 2018. Review.


GATA4 Variants in Individuals With a 46,XY Disorder of Sex Development (DSD) May or May Not Be Associated With Cardiac Defects Depending on Second Hits in Other DSD Genes.

Martinez de LaPiscina I, de Mingo C, Riedl S, Rodriguez A, Pandey AV, Fernández-Cancio M, Camats N, Sinclair A, Castaño L, Audi L, Flück CE.

Front Endocrinol (Lausanne). 2018 Apr 4;9:142. doi: 10.3389/fendo.2018.00142. eCollection 2018.


Adiponectin-leptin ratio: A promising index to estimate adipose tissue dysfunction. Relation with obesity-associated cardiometabolic risk.

Frühbeck G, Catalán V, Rodríguez A, Gómez-Ambrosi J.

Adipocyte. 2018 Jan 2;7(1):57-62. doi: 10.1080/21623945.2017.1402151. Epub 2017 Dec 5.


Increased Small Intestine Expression of Non-Heme Iron Transporters in Morbidly Obese Patients With Newly Diagnosed Type 2 Diabetes.

Moreno-Navarrete JM, Rodríguez A, Becerril S, Valentí V, Salvador J, Frühbeck G, Fernández-Real JM.

Mol Nutr Food Res. 2018 Jan;62(2). doi: 10.1002/mnfr.201700301. Epub 2017 Dec 29.


The increase in fiber size in male rat gastrocnemius after chronic central leptin infusion is related to activation of insulin signaling.

Burgos-Ramos E, Canelles S, Rodríguez A, Frago LM, Gómez-Ambrosi J, Chowen JA, Frühbeck G, Argente J, Barrios V.

Mol Cell Endocrinol. 2018 Jul 15;470:48-59. doi: 10.1016/j.mce.2017.09.029. Epub 2017 Sep 27.


Heme Biosynthetic Pathway is Functionally Linked to Adipogenesis via Mitochondrial Respiratory Activity.

Moreno-Navarrete JM, Rodríguez A, Ortega F, Becerril S, Girones J, Sabater-Masdeu M, Latorre J, Ricart W, Frühbeck G, Fernández-Real JM.

Obesity (Silver Spring). 2017 Oct;25(10):1723-1733. doi: 10.1002/oby.21956. Epub 2017 Aug 31.


IL-32α-induced inflammation constitutes a link between obesity and colon cancer.

Catalán V, Gómez-Ambrosi J, Rodríguez A, Ramírez B, Ortega VA, Hernández-Lizoain JL, Baixauli J, Becerril S, Rotellar F, Valentí V, Moncada R, Silva C, Salvador J, Frühbeck G.

Oncoimmunology. 2017 May 16;6(7):e1328338. doi: 10.1080/2162402X.2017.1328338. eCollection 2017.


Involvement of the leptin-adiponectin axis in inflammation and oxidative stress in the metabolic syndrome.

Frühbeck G, Catalán V, Rodríguez A, Ramírez B, Becerril S, Salvador J, Portincasa P, Colina I, Gómez-Ambrosi J.

Sci Rep. 2017 Jul 26;7(1):6619. doi: 10.1038/s41598-017-06997-0.

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