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Items: 1 to 20 of 28


Investigation of cell culture conditions for optimal foot-and-mouth disease virus production.

Dill V, Zimmer A, Beer M, Eschbaumer M.

BMC Biotechnol. 2019 Jun 7;19(1):33. doi: 10.1186/s12896-019-0527-5.


Cell Density Effects in Different Cell Culture Media and Their Impact on the Propagation of Foot-And-Mouth Disease Virus.

Dill V, Ehret J, Zimmer A, Beer M, Eschbaumer M.

Viruses. 2019 Jun 4;11(6). pii: E511. doi: 10.3390/v11060511.


Vitamins in cell culture media: Stability and stabilization strategies.

Schnellbaecher A, Binder D, Bellmaine S, Zimmer A.

Biotechnol Bioeng. 2019 Jun;116(6):1537-1555. doi: 10.1002/bit.26942. Epub 2019 Feb 21. Review.


Comparison of plasma and oral fluid concentrations of mycophenolic acid and its glucuronide metabolite by LC-MS in kidney transplant patients.

Ferreira PCL, Thiesen FV, de Araujo TT, D'Ávila DO, Gadonski G, de Oliveira CSA, Zimmer AR, Fröehlich PE.

Eur J Clin Pharmacol. 2019 Apr;75(4):553-559. doi: 10.1007/s00228-018-02614-9. Epub 2019 Jan 4.


Impact of cell culture media additives on IgG glycosylation produced in Chinese hamster ovary cells.

Ehret J, Zimmermann M, Eichhorn T, Zimmer A.

Biotechnol Bioeng. 2019 Apr;116(4):816-830. doi: 10.1002/bit.26904. Epub 2019 Jan 21.


Rapid tools to gain insights into the interaction dynamics of new 8-hydroxyquinolines with few fungal lines.

Joaquim AR, Pippi B, de Cesare MA, Rocha DA, Boff RT, Staudt KJ, Ruaro TC, Zimmer AR, de Araújo BV, Silveira GP, Martins AF, Teixeira ML, Dos Santos FP, Fuentefria AM, de Andrade SF.

Chem Biol Drug Des. 2018 Nov 19. doi: 10.1111/cbdd.13435. [Epub ahead of print]


SERCA plays a crucial role in the toxicity of a betulinic acid derivative with potential antimalarial activity.

Diedrich D, Wildner AC, Silveira TF, Silva GNS, Santos FD, da Silva EF, do Canto VP, Visioli F, Gosmann G, Bergold AM, Zimmer AR, Netz PA, Gnoatto SCB.

Chem Biol Interact. 2018 May 1;287:70-77. doi: 10.1016/j.cbi.2018.03.014. Epub 2018 Mar 28.


Influence of cell type and cell culture media on the propagation of foot-and-mouth disease virus with regard to vaccine quality.

Dill V, Hoffmann B, Zimmer A, Beer M, Eschbaumer M.

Virol J. 2018 Mar 16;15(1):46. doi: 10.1186/s12985-018-0956-0.


Adaption of FMDV Asia-1 to Suspension Culture: Cell Resistance Is Overcome by Virus Capsid Alterations.

Dill V, Hoffmann B, Zimmer A, Beer M, Eschbaumer M.

Viruses. 2017 Aug 18;9(8). pii: E231. doi: 10.3390/v9080231.


Impact of S-sulfocysteine on fragments and trisulfide bond linkages in monoclonal antibodies.

Seibel R, Maier S, Schnellbaecher A, Bohl S, Wehsling M, Zeck A, Zimmer A.

MAbs. 2017 Aug/Sep;9(6):889-897. doi: 10.1080/19420862.2017.1333212. Epub 2017 Jun 5.


Design, Synthesis and Biological Evaluation of Betulinic Acid Derivatives as New Antitumor Agents for Leukemia.

Waechter F, da Silva GNS, Willig JB, de Oliveira CB, Vieira BD, Trivella DBB, Zimmer AR, Buffon A, Pilger DA, Gnoatto SCB.

Anticancer Agents Med Chem. 2017;17(13):1777-1785. doi: 10.2174/1871521409666170412143638.


Antioxidant effect of thiazolidine molecules in cell culture media improves stability and performance.

Kuschelewski J, Schnellbaecher A, Pering S, Wehsling M, Zimmer A.

Biotechnol Prog. 2017 May;33(3):759-770. doi: 10.1002/btpr.2458. Epub 2017 Mar 23.


Vaccinium virgatum fruit extract as an important adjuvant in biochemical and behavioral alterations observed in animal model of metabolic syndrome.

Oliveira PS, Gazal M, Flores NP, Zimmer AR, Chaves VC, Reginatto FH, Kaster MP, Tavares RG, Spanevello RM, Lencina CL, Stefanello FM.

Biomed Pharmacother. 2017 Apr;88:939-947. doi: 10.1016/j.biopha.2017.01.121. Epub 2017 Feb 6.


Red Pepper (Capsicum baccatum) Extracts Present Anti-Inflammatory Effects In Vivo and Inhibit the Production of TNF-α and NO In Vitro.

Allemand A, Leonardi BF, Zimmer AR, Moreno S, Romão PR, Gosmann G.

J Med Food. 2016 Aug;19(8):759-67. doi: 10.1089/jmf.2015.0101.


S-Sulfocysteine simplifies fed-batch processes and increases the CHO specific productivity via anti-oxidant activity.

Hecklau C, Pering S, Seibel R, Schnellbaecher A, Wehsling M, Eichhorn T, Hagen Jv, Zimmer A.

J Biotechnol. 2016 Jan 20;218:53-63. doi: 10.1016/j.jbiotec.2015.11.022. Epub 2015 Dec 2.


Cotinine and polycyclic aromatic hydrocarbons levels in the amniotic fluid and fetal cord at birth and in the urine from pregnant smokers.

Machado Jde B, Chatkin JM, Zimmer AR, Goulart AP, Thiesen FV.

PLoS One. 2014 Dec 30;9(12):e116293. doi: 10.1371/journal.pone.0116293. eCollection 2014.


Mid-infrared spectroscopy-based analysis of mammalian cell culture parameters.

Capito F, Zimmer A, Skudas R.

Biotechnol Prog. 2015 Mar-Apr;31(2):578-84. doi: 10.1002/btpr.2026. Epub 2015 Jan 19.


Changes in Brain 14-3-3 Proteins in Response to Insulin Resistance Induced by a High Palatable Diet.

Bock H, Zimmer AR, Zimmer ER, de Souza DO, Portela LV, Saraiva-Pereira ML.

Mol Neurobiol. 2015 Aug;52(1):710-8. doi: 10.1007/s12035-014-8905-4. Epub 2014 Oct 4.


Improvement and simplification of fed-batch bioprocesses with a highly soluble phosphotyrosine sodium salt.

Zimmer A, Mueller R, Wehsling M, Schnellbaecher A, von Hagen J.

J Biotechnol. 2014 Sep 30;186:110-8. doi: 10.1016/j.jbiotec.2014.06.026. Epub 2014 Jul 9.


Nandrolone-induced aggressive behavior is associated with alterations in extracellular glutamate homeostasis in mice.

Kalinine E, Zimmer ER, Zenki KC, Kalinine I, Kazlauckas V, Haas CB, Hansel G, Zimmer AR, Souza DO, Müller AP, Portela LV.

Horm Behav. 2014 Jul;66(2):383-92. doi: 10.1016/j.yhbeh.2014.06.005. Epub 2014 Jun 14.

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