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Items: 17

1.

Curcumin Analogue C1 Promotes Hex and Gal Recruitment to the Plasma Membrane via mTORC1-Independent TFEB Activation.

Magini A, Polchi A, Di Meo D, Buratta S, Chiaradia E, Germani R, Emiliani C, Tancini B.

Int J Mol Sci. 2019 Mar 18;20(6). pii: E1363. doi: 10.3390/ijms20061363.

2.

Biocompatible Polymer Nanoparticles for Drug Delivery Applications in Cancer and Neurodegenerative Disorder Therapies.

Calzoni E, Cesaretti A, Polchi A, Di Michele A, Tancini B, Emiliani C.

J Funct Biomater. 2019 Jan 8;10(1). pii: E4. doi: 10.3390/jfb10010004. Review.

3.

Early intrathecal infusion of everolimus restores cognitive function and mood in a murine model of Alzheimer's disease.

Cassano T, Magini A, Giovagnoli S, Polchi A, Calcagnini S, Pace L, Lavecchia MA, Scuderi C, Bronzuoli MR, Ruggeri L, Gentileschi MP, Romano A, Gaetani S, De Marco F, Emiliani C, Dolcetta D.

Exp Neurol. 2019 Jan;311:88-105. doi: 10.1016/j.expneurol.2018.09.011. Epub 2018 Sep 20.

PMID:
30243986
4.

mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model.

Polchi A, Magini A, Meo DD, Tancini B, Emiliani C.

Int J Mol Sci. 2018 May 16;19(5). pii: E1474. doi: 10.3390/ijms19051474. Review.

5.

TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells.

Magini A, Polchi A, Di Meo D, Mariucci G, Sagini K, De Marco F, Cassano T, Giovagnoli S, Dolcetta D, Emiliani C.

Hum Mol Genet. 2017 Sep 1;26(17):3303-3312. doi: 10.1093/hmg/ddx214.

PMID:
28637240
6.

Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization.

Polchi A, Magini A, Mazuryk J, Tancini B, Gapiński J, Patkowski A, Giovagnoli S, Emiliani C.

Nanomaterials (Basel). 2016 May 9;6(5). pii: E87. doi: 10.3390/nano6050087.

7.

Evaluation of a LC-MS method for everolimus preclinical determination in brain by using [(13)C2D4]RAD001 internal standard.

Giovagnoli S, Cassano T, Pace L, Magini A, Polchi A, Tancini B, Perluigi M, De Marco F, Emiliani C, Dolcetta D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Mar 15;985:155-63. doi: 10.1016/j.jchromb.2015.01.035. Epub 2015 Feb 3.

PMID:
25682337
8.

Abnormal cortical lysosomal β-hexosaminidase and β-galactosidase activity at post-synaptic sites during Alzheimer's disease progression.

Magini A, Polchi A, Tozzi A, Tancini B, Tantucci M, Urbanelli L, Borsello T, Calabresi P, Emiliani C.

Int J Biochem Cell Biol. 2015 Jan;58:62-70. doi: 10.1016/j.biocel.2014.11.001. Epub 2014 Nov 12.

PMID:
25462158
9.

Oncogenic H-Ras up-regulates acid β-hexosaminidase by a mechanism dependent on the autophagy regulator TFEB.

Urbanelli L, Magini A, Ercolani L, Sagini K, Polchi A, Tancini B, Brozzi A, Armeni T, Principato G, Emiliani C.

PLoS One. 2014 Feb 24;9(2):e89485. doi: 10.1371/journal.pone.0089485. eCollection 2014.

10.

Methods to discriminate the distribution of acidic glycohydrolases between the endosomal-lysosomal systems and the plasma membrane.

Magini A, Polchi A, Tancini B, Urbanelli L, Di Cristina M, Mannucci R, Nicoletti I, Emiliani C.

Methods Enzymol. 2014;534:25-45. doi: 10.1016/B978-0-12-397926-1.00002-0.

PMID:
24359946
11.

Chaperone therapy for GM2 gangliosidosis: effects of pyrimethamine on β-hexosaminidase activity in Sandhoff fibroblasts.

Chiricozzi E, Niemir N, Aureli M, Magini A, Loberto N, Prinetti A, Bassi R, Polchi A, Emiliani C, Caillaud C, Sonnino S.

Mol Neurobiol. 2014 Aug;50(1):159-67. doi: 10.1007/s12035-013-8605-5. Epub 2013 Dec 20. Review.

PMID:
24356898
12.

TFEB activation promotes the recruitment of lysosomal glycohydrolases β-hexosaminidase and β-galactosidase to the plasma membrane.

Magini A, Polchi A, Urbanelli L, Cesselli D, Beltrami A, Tancini B, Emiliani C.

Biochem Biophys Res Commun. 2013 Oct 18;440(2):251-7. doi: 10.1016/j.bbrc.2013.09.060. Epub 2013 Sep 20. Erratum in: Biochem Biophys Res Commun. 2014 Jan 3;443(1):344.

PMID:
24055709
13.

Signaling pathways in exosomes biogenesis, secretion and fate.

Urbanelli L, Magini A, Buratta S, Brozzi A, Sagini K, Polchi A, Tancini B, Emiliani C.

Genes (Basel). 2013 Mar 28;4(2):152-70. doi: 10.3390/genes4020152.

14.

Β-hexosaminidase over-expression affects lysosomal glycohydrolases expression and glycosphingolipid metabolism in mammalian cells.

Tancini B, Magini A, Bortot B, Polchi A, Urbanelli L, Sonnino S, Severini GM, Emiliani C.

Mol Cell Biochem. 2012 Apr;363(1-2):109-18. doi: 10.1007/s11010-011-1163-0. Epub 2011 Dec 7.

PMID:
22147196
15.

Glycohydrolases β-hexosaminidase and β-galactosidase are associated with lipid microdomains of Jurkat T-lymphocytes.

Magini A, Polchi A, Tancini B, Urbanelli L, Hasilik A, Emiliani C.

Biochimie. 2012 Mar;94(3):684-94. doi: 10.1016/j.biochi.2011.09.021. Epub 2011 Sep 29.

PMID:
21978926
16.

Human lysosomal α-D-mannosidase regulation in promyelocytic leukaemia cells.

Urbanelli L, Magini A, Ercolani L, Trivelli F, Polchi A, Tancini B, Emiliani C.

Biosci Rep. 2011 Dec;31(6):477-87. doi: 10.1042/BSR20110020.

PMID:
21521175
17.

Recent developments in therapeutic approaches for lysosomal storage diseases.

Urbanelli L, Magini A, Polchi A, Polidoro M, Emiliani C.

Recent Pat CNS Drug Discov. 2011 Jan;6(1):1-19. Review.

PMID:
21073432

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