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Items: 1 to 20 of 21


Chemical Structures and Pharmacological Profiles of Ginseng Saponins.

Shi ZY, Zeng JZ, Wong AST.

Molecules. 2019 Jul 3;24(13). pii: E2443. doi: 10.3390/molecules24132443. Review.


FAM83D promotes ovarian cancer progression and its potential application in diagnosis of invasive ovarian cancer.

Zhang Q, Yu S, Lok SIS, Wong AST, Jiao Y, Lee LTO.

J Cell Mol Med. 2019 Jul;23(7):4569-4581. doi: 10.1111/jcmm.14360. Epub 2019 Apr 30.


Angiotensin II promotes ovarian cancer spheroid formation and metastasis by upregulation of lipid desaturation and suppression of endoplasmic reticulum stress.

Zhang Q, Yu S, Lam MMT, Poon TCW, Sun L, Jiao Y, Wong AST, Lee LTO.

J Exp Clin Cancer Res. 2019 Mar 7;38(1):116. doi: 10.1186/s13046-019-1127-x.


Hypoxia Causes Transgenerational Impairment of Ovarian Development and Hatching Success in Fish.

Lai KP, Wang SY, Li JW, Tong Y, Chan TF, Jin N, Tse A, Zhang JW, Wan MT, Tam N, Au DWT, Lee BY, Lee JS, Wong AST, Kong RYC, Wu RSS.

Environ Sci Technol. 2019 Apr 2;53(7):3917-3928. doi: 10.1021/acs.est.8b07250. Epub 2019 Mar 22.


Nuclear Met promotes hepatocellular carcinoma tumorigenesis and metastasis by upregulation of TAK1 and activation of NF-κB pathway.

Tey SK, Tse EYT, Mao X, Ko FCF, Wong AST, Lo RC, Ng IO, Yam JWP.

Cancer Lett. 2017 Dec 28;411:150-161. doi: 10.1016/j.canlet.2017.09.047. Epub 2017 Oct 6.


Combined low-dose zearalenone and aflatoxin B1 on cell growth and cell-cycle progression in breast cancer MCF-7 cells.

Yip KY, Wan MLY, Wong AST, Korach KS, El-Nezami H.

Toxicol Lett. 2017 Nov 5;281:139-151. doi: 10.1016/j.toxlet.2017.09.022. Epub 2017 Sep 28.


The Role of Endocrine G Protein-Coupled Receptors in Ovarian Cancer Progression.

Zhang Q, Madden NE, Wong AST, Chow BKC, Lee LTO.

Front Endocrinol (Lausanne). 2017 Apr 7;8:66. doi: 10.3389/fendo.2017.00066. eCollection 2017. Review.


Targeting to the non-genomic activity of retinoic acid receptor-gamma by acacetin in hepatocellular carcinoma.

Zeng W, Zhang C, Cheng H, Wu YL, Liu J, Chen Z, Huang JG, Ericksen RE, Chen L, Zhang H, Wong AS, Zhang XK, Han W, Zeng JZ.

Sci Rep. 2017 Mar 23;7(1):348. doi: 10.1038/s41598-017-00233-5.


Nanomechanical measurement of adhesion and migration of leukemia cells with phorbol 12-myristate 13-acetate treatment.

Zhou ZL, Ma J, Tong MH, Chan BP, Wong AS, Ngan AH.

Int J Nanomedicine. 2016 Dec 7;11:6533-6545. eCollection 2016.


TRC4, an improved triptolide derivative, specifically targets to truncated form of retinoid X receptor-alpha in cancer cells.

Wang PY, Zeng WJ, Liu J, Wu YL, Ma Y, Zeng Z, Pang JY, Zhang XK, Yan X, Wong AST, Zeng JZ.

Biochem Pharmacol. 2017 Jan 15;124:19-28. doi: 10.1016/j.bcp.2016.10.014. Epub 2016 Oct 31.


Enhanced anti-cancer activities of a gold(III) pyrrolidinedithiocarbamato complex incorporated in a biodegradable metal-organic framework.

Sun RW, Zhang M, Li D, Li M, Wong AS.

J Inorg Biochem. 2016 Oct;163:1-7. doi: 10.1016/j.jinorgbio.2016.06.020. Epub 2016 Jun 16.


A novel p70 S6 kinase-microRNA biogenesis axis mediates multicellular spheroid formation in ovarian cancer progression.

Lam SS, Ip CK, Mak AS, Wong AS.

Oncotarget. 2016 Jun 21;7(25):38064-38077. doi: 10.18632/oncotarget.9345.


Hypoxia causes transgenerational impairments in reproduction of fish.

Wang SY, Lau K, Lai KP, Zhang JW, Tse AC, Li JW, Tong Y, Chan TF, Wong CK, Chiu JM, Au DW, Wong AS, Kong RY, Wu RS.

Nat Commun. 2016 Jul 4;7:12114. doi: 10.1038/ncomms12114.


Dinuclear Gold(I) Pyrrolidinedithiocarbamato Complex: Cytotoxic and Antimigratory Activities on Cancer Cells and the Use of Metal-Organic Framework.

Sun RW, Zhang M, Li D, Zhang ZF, Cai H, Li M, Xian YJ, Ng SW, Wong AS.

Chemistry. 2015 Dec 14;21(51):18534-8. doi: 10.1002/chem.201503656. Epub 2015 Oct 29.


Combination of dendrimer-nanovector-mediated small interfering RNA delivery to target Akt with the clinical anticancer drug paclitaxel for effective and potent anticancer activity in treating ovarian cancer.

Kala S, Mak AS, Liu X, Posocco P, Pricl S, Peng L, Wong AS.

J Med Chem. 2014 Mar 27;57(6):2634-42. doi: 10.1021/jm401907z. Epub 2014 Mar 18.


A gold(III) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells.

Lum CT, Wong AS, Lin MC, Che CM, Sun RW.

Chem Commun (Camb). 2013 May 14;49(39):4364-6. doi: 10.1039/c2cc37366a. Epub 2012 Dec 7.


Caveolin-1 overexpression is associated with hepatocellular carcinoma tumourigenesis and metastasis.

Tse EY, Ko FC, Tung EK, Chan LK, Lee TK, Ngan ES, Man K, Wong AS, Ng IO, Yam JW.

J Pathol. 2012 Mar;226(4):645-53. doi: 10.1002/path.3957. Epub 2012 Jan 4.


Regulation of Nur77 expression by β-catenin and its mitogenic effect in colon cancer cells.

Wu H, Lin Y, Li W, Sun Z, Gao W, Zhang H, Xie L, Jiang F, Qin B, Yan T, Chen L, Zhao Y, Cao X, Wu Y, Lin B, Zhou H, Wong AS, Zhang XK, Zeng JZ.

FASEB J. 2011 Jan;25(1):192-205. doi: 10.1096/fj.10-166462. Epub 2010 Sep 16.

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