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Items: 1 to 20 of 38

1.

Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation.

Santos I, Ramos C, Mendes C, Sequeira CO, Tomé CS, Fernandes DGH, Mota P, Pires RF, Urso D, Hipólito A, Antunes AMM, Vicente JB, Pereira SA, Bonifácio VDB, Nunes SC, Serpa J.

Nutrients. 2019 Oct 19;11(10). pii: E2523. doi: 10.3390/nu11102523.

2.

A Metabolomics-Inspired Strategy for the Identification of Protein Covalent Modifications.

Nunes J, Charneira C, Nunes C, Gouveia-Fernandes S, Serpa J, Morello J, Antunes AMM.

Front Chem. 2019 Jul 31;7:532. doi: 10.3389/fchem.2019.00532. eCollection 2019.

3.

Special Issue "Adductomics: Elucidating the Environmental Causes of Disease".

Pereira SA, Antunes AMM.

High Throughput. 2019 Jul 31;8(3). pii: E17. doi: 10.3390/ht8030017.

4.

The mercapturomic profile of health and non-communicable diseases.

Gonçalves-Dias C, Morello J, Semedo V, Correia MJ, Coelho NR, Monteiro EC, Antunes AMM, Pereira SA.

High Throughput. 2019 Apr 23;8(2). pii: E10. doi: 10.3390/ht8020010. Review.

5.

Mass Spectrometry-Based Methodologies for Targeted and Untargeted Identification of Protein Covalent Adducts (Adductomics): Current Status and Challenges.

Nunes J, Charneira C, Morello J, Rodrigues J, Pereira SA, Antunes AMM.

High Throughput. 2019 Apr 23;8(2). pii: E9. doi: 10.3390/ht8020009. Review.

6.

Severe Acute Kidney Injury and Double Tubulopathy Due to Dual Toxicity Caused by Combination Antiretroviral Therapy.

Soto K, Campos P, Manso R, Antunes AMM, Morello J, Perazella MA.

Kidney Int Rep. 2018 Nov 28;4(3):494-499. doi: 10.1016/j.ekir.2018.11.014. eCollection 2019 Mar. No abstract available.

7.

Genotoxic and Epigenotoxic Alterations in the Lung and Liver of Mice Induced by Acrylamide: A 28 Day Drinking Water Study.

de Conti A, Tryndyak V, VonTungeln LS, Churchwell MI, Beland FA, Antunes AMM, Pogribny IP.

Chem Res Toxicol. 2019 May 20;32(5):869-877. doi: 10.1021/acs.chemrestox.9b00020. Epub 2019 Mar 12.

PMID:
30807115
8.

Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity.

Marinho AT, Miranda JP, Caixas U, Charneira C, Gonçalves-Dias C, Marques MM, Monteiro EC, Antunes AMM, Pereira SA.

Drug Metab Rev. 2019 Feb;51(1):76-90. doi: 10.1080/03602532.2019.1577891. Epub 2019 Mar 29. Review.

PMID:
30712401
9.

Mercapturate Pathway in the Tubulocentric Perspective of Diabetic Kidney Disease.

Gonçalves-Dias C, Morello J, Correia MJ, Coelho NR, Antunes AMM, Macedo MP, Monteiro EC, Soto K, Pereira SA.

Nephron. 2019;143(1):17-23. doi: 10.1159/000494390. Epub 2019 Jan 9. Review.

10.

The first-line antiepileptic drug carbamazepine: Reaction with biologically relevant free radicals.

Martins IL, Nunes J, Charneira C, Morello J, Pereira SA, Telo JP, Marques MM, Antunes AMM.

Free Radic Biol Med. 2018 Dec;129:559-568. doi: 10.1016/j.freeradbiomed.2018.10.408. Epub 2018 Oct 17.

PMID:
30342189
11.

High resolution mass spectrometry-based methodologies for identification of Etravirine bioactivation to reactive metabolites: In vitro and in vivo approaches.

Godinho ALA, Martins IL, Nunes J, Charneira C, Grilo J, Silva DM, Pereira SA, Soto K, Oliveira MC, Marques MM, Jacob CC, Antunes AMM.

Eur J Pharm Sci. 2018 Jul 1;119:70-82. doi: 10.1016/j.ejps.2018.03.026. Epub 2018 Mar 26.

PMID:
29592839
12.

Integration of cellular and molecular endpoints to assess the toxicity of polycyclic aromatic hydrocarbons in HepG2 cell line.

Morgado PI, Jose S, Wanke R, M Antunes AM, Cardoso AS, Jordao L.

Environ Toxicol Chem. 2017 Dec;36(12):3404-3414. doi: 10.1002/etc.3927. Epub 2017 Sep 8.

PMID:
28731233
13.

Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms.

Grilo NM, João Correia M, Miranda JP, Cipriano M, Serpa J, Matilde Marques M, Monteiro EC, Antunes AMM, Diogo LN, Pereira SA.

Eur J Pharm Sci. 2017 Jul 15;105:47-54. doi: 10.1016/j.ejps.2017.05.010. Epub 2017 May 6.

PMID:
28487145
14.

New insights into the molecular mechanisms of chemical carcinogenesis: In vivo adduction of histone H2B by a reactive metabolite of the chemical carcinogen furan.

Nunes J, Martins IL, Charneira C, Pogribny IP, de Conti A, Beland FA, Marques MM, Jacob CC, Antunes AMM.

Toxicol Lett. 2016 Dec 15;264:106-113. doi: 10.1016/j.toxlet.2016.10.018. Epub 2016 Nov 5.

PMID:
27825936
15.

Efavirenz biotransformation as an up-stream event of mood changes in HIV-infected patients.

Grilo NM, Correia MJ, Sequeira C, Harjivan SG, Caixas U, Diogo LN, Marques MM, Monteiro EC, Antunes AM, Pereira SA.

Toxicol Lett. 2016 Oct 17;260:28-35. doi: 10.1016/j.toxlet.2016.08.009. Epub 2016 Aug 16.

PMID:
27543169
16.

Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study.

Pinheiro PF, Pereira SA, Harjivan SG, Martins IL, Marinho AT, Cipriano M, Jacob CC, Oliveira NG, Castro MF, Marques MM, Antunes AMM, Miranda JP.

Arch Toxicol. 2017 Mar;91(3):1199-1211. doi: 10.1007/s00204-016-1792-x. Epub 2016 Jul 14.

PMID:
27417440
17.

Nevirapine modulation of paraoxonase-1 in the liver: An in vitro three-model approach.

Marinho AT, Dias CG, Pinheiro PF, Lemos AR, Antunes AM, Marques MM, Monteiro EC, Miranda JP, Pereira SA.

Eur J Pharm Sci. 2016 Jan 20;82:147-53. doi: 10.1016/j.ejps.2015.11.019. Epub 2015 Nov 25.

PMID:
26620700
18.

Selenium-containing chrysin and quercetin derivatives: attractive scaffolds for cancer therapy.

Martins IL, Charneira C, Gandin V, Ferreira da Silva JL, Justino GC, Telo JP, Vieira AJ, Marzano C, Antunes AM.

J Med Chem. 2015 May 28;58(10):4250-65. doi: 10.1021/acs.jmedchem.5b00230. Epub 2015 May 7.

PMID:
25906385
19.

The phenolic metabolites of the anti-HIV drug efavirenz: evidence for distinct reactivities upon oxidation with Frémy's salt.

Harjivan SG, Wanke R, Ferreira da Silva JL, Marques MM, Antunes AM.

Eur J Med Chem. 2014 Mar 3;74:7-11. doi: 10.1016/j.ejmech.2013.12.022. Epub 2013 Dec 31.

PMID:
24440376
20.

Electronic communication in linear oligo(azobenzene) radical anions.

Moneo Á, Justino GC, Carvalho MF, Oliveira MC, Antunes AM, Bléger D, Hecht S, Telo JP.

J Phys Chem A. 2013 Dec 27;117(51):14056-64. doi: 10.1021/jp407099c. Epub 2013 Dec 5.

PMID:
24308386

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