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Master of disguise: hepatitis delta virus packaging and spread facilitated by diverse viral envelope proteins.

Maya S, Ploss A.

Hepatology. 2019 Aug 29. doi: 10.1002/hep.30922. [Epub ahead of print]


Hepatitis E Virus Replication.

LeDesma R, Nimgaonkar I, Ploss A.

Viruses. 2019 Aug 6;11(8). pii: E719. doi: 10.3390/v11080719. Review.


Analysis of Host Responses to Hepatitis B and Delta Viral Infections in a Micro-scalable Hepatic Co-culture System.

Winer BY, Gaska JM, Lipkowitz G, Bram Y, Parekh A, Parsons L, Leach R, Jindal R, Cho CH, Shrirao A, Novik E, Schwartz RE, Ploss A.

Hepatology. 2019 Jun 17. doi: 10.1002/hep.30815. [Epub ahead of print]


Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus.

Gaska JM, Balev M, Ding Q, Heller B, Ploss A.

Elife. 2019 May 10;8. pii: e44436. doi: 10.7554/eLife.44436.


Decoding type I and III interferon signalling during viral infection.

Mesev EV, LeDesma RA, Ploss A.

Nat Microbiol. 2019 Jun;4(6):914-924. doi: 10.1038/s41564-019-0421-x. Epub 2019 Apr 1. Review.


Mouse Models for Studying HCV Vaccines and Therapeutic Antibodies.

Gaska JM, Ding Q, Ploss A.

Methods Mol Biol. 2019;1911:481-503. doi: 10.1007/978-1-4939-8976-8_33.


Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses.

Douam F, Ziegler CGK, Hrebikova G, Fant B, Leach R, Parsons L, Wang W, Gaska JM, Winer BY, Heller B, Shalek AK, Ploss A.

Nat Commun. 2018 Nov 28;9(1):5031. doi: 10.1038/s41467-018-07478-2.


Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection.

Winer BY, Shirvani-Dastgerdi E, Bram Y, Sellau J, Low BE, Johnson H, Huang T, Hrebikova G, Heller B, Sharon Y, Giersch K, Gerges S, Seneca K, Pais MA, Frankel AS, Chiriboga L, Cullen J, Nahass RG, Lutgehetmann M, Toettcher JE, Wiles MV, Schwartz RE, Ploss A.

Sci Transl Med. 2018 Jun 27;10(447). pii: eaap9328. doi: 10.1126/scitranslmed.aap9328.


Yellow Fever Virus: Knowledge Gaps Impeding the Fight Against an Old Foe.

Douam F, Ploss A.

Trends Microbiol. 2018 Nov;26(11):913-928. doi: 10.1016/j.tim.2018.05.012. Epub 2018 Jun 19. Review.


Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease.

Ding Q, Gaska JM, Douam F, Wei L, Kim D, Balev M, Heller B, Ploss A.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6310-E6318. doi: 10.1073/pnas.1803406115. Epub 2018 Jun 18.


Identification of the Intragenomic Promoter Controlling Hepatitis E Virus Subgenomic RNA Transcription.

Ding Q, Nimgaonkar I, Archer NF, Bram Y, Heller B, Schwartz RE, Ploss A.

MBio. 2018 May 8;9(3). pii: e00769-18. doi: 10.1128/mBio.00769-18.


Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice.

Dragovic SM, Agunbiade TA, Freudzon M, Yang J, Hastings AK, Schleicher TR, Zhou X, Craft S, Chuang YM, Gonzalez F, Li Y, Hrebikova G, Tripathi A, Mlambo G, Almeras L, Ploss A, Dimopoulos G, Fikrig E.

Cell Host Microbe. 2018 Apr 11;23(4):523-535.e5. doi: 10.1016/j.chom.2018.03.008.


The use of humanized mice for studies of viral pathogenesis and immunity.

Douam F, Ploss A.

Curr Opin Virol. 2018 Apr;29:62-71. doi: 10.1016/j.coviro.2018.03.003. Epub 2018 Mar 28. Review.


A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism.

Douam F, Fusil F, Enguehard M, Dib L, Nadalin F, Schwaller L, Hrebikova G, Mancip J, Mailly L, Montserret R, Ding Q, Maisse C, Carlot E, Xu K, Verhoeyen E, Baumert TF, Ploss A, Carbone A, Cosset FL, Lavillette D.

PLoS Pathog. 2018 Mar 5;14(3):e1006908. doi: 10.1371/journal.ppat.1006908. eCollection 2018 Mar.


Hepatitis E virus: advances and challenges.

Nimgaonkar I, Ding Q, Schwartz RE, Ploss A.

Nat Rev Gastroenterol Hepatol. 2018 Feb;15(2):96-110. doi: 10.1038/nrgastro.2017.150. Epub 2017 Nov 22. Review.


A porcine model for chronic hepatitis E.

Nimgaonkar I, Ploss A.

Hepatology. 2018 Feb;67(2):787-790. doi: 10.1002/hep.29566. Epub 2018 Jan 1. No abstract available.


Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection In Vivo.

Douam F, Soto Albrecht YE, Hrebikova G, Sadimin E, Davidson C, Kotenko SV, Ploss A.

MBio. 2017 Aug 15;8(4). pii: e00819-17. doi: 10.1128/mBio.00819-17.


Long-term hepatitis B infection in a scalable hepatic co-culture system.

Winer BY, Huang TS, Pludwinski E, Heller B, Wojcik F, Lipkowitz GE, Parekh A, Cho C, Shrirao A, Muir TW, Novik E, Ploss A.

Nat Commun. 2017 Jul 25;8(1):125. doi: 10.1038/s41467-017-00200-8.


Immunization With a Subunit Hepatitis C Virus Vaccine Elicits Pan-Genotypic Neutralizing Antibodies and Intrahepatic T-Cell Responses in Nonhuman Primates.

Li D, Wang X, von Schaewen M, Tao W, Zhang Y, Heller B, Hrebikova G, Deng Q, Sun Q, Ploss A, Zhong J, Huang Z.

J Infect Dis. 2017 Jun 15;215(12):1824-1831. doi: 10.1093/infdis/jix180.


Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy.

Shirvani-Dastgerdi E, Winer BY, Celià-Terrassa T, Kang Y, Tabernero D, Yagmur E, Rodríguez-Frías F, Gregori J, Luedde T, Trautwein C, Ploss A, Tacke F.

J Hepatol. 2017 Aug;67(2):246-254. doi: 10.1016/j.jhep.2017.03.027. Epub 2017 Apr 7.

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