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Items: 1 to 20 of 104

1.

Latest advances in aging research and drug discovery.

Bakula D, Ablasser A, Aguzzi A, Antebi A, Barzilai N, Bittner MI, Jensen MB, Calkhoven CF, Chen D, Grey ADNJ, Feige JN, Georgievskaya A, Gladyshev VN, Golato T, Gudkov AV, Hoppe T, Kaeberlein M, Katajisto P, Kennedy BK, Lal U, Martin-Villalba A, Moskalev AA, Ozerov I, Petr MA, Reason, Rubinsztein DC, Tyshkovskiy A, Vanhaelen Q, Zhavoronkov A, Scheibye-Knudsen M.

Aging (Albany NY). 2019 Nov 21;11. doi: 10.18632/aging.102487. [Epub ahead of print]

2.

Deep biomarkers of aging and longevity: from research to applications.

Zhavoronkov A, Li R, Ma C, Mamoshina P.

Aging (Albany NY). 2019 Nov 25;11. doi: 10.18632/aging.102475. [Epub ahead of print]

3.

Identification of Novel Antibacterials Using Machine Learning Techniques.

Ivanenkov YA, Zhavoronkov A, Yamidanov RS, Osterman IA, Sergiev PV, Aladinskiy VA, Aladinskaya AV, Terentiev VA, Veselov MS, Ayginin AA, Kartsev VG, Skvortsov DA, Chemeris AV, Baimiev AK, Sofronova AA, Malyshev AS, Filkov GI, Bezrukov DS, Zagribelnyy BA, Putin EO, Puchinina MM, Dontsova OA.

Front Pharmacol. 2019 Aug 27;10:913. doi: 10.3389/fphar.2019.00913. eCollection 2019.

4.

Deep learning enables rapid identification of potent DDR1 kinase inhibitors.

Zhavoronkov A, Ivanenkov YA, Aliper A, Veselov MS, Aladinskiy VA, Aladinskaya AV, Terentiev VA, Polykovskiy DA, Kuznetsov MD, Asadulaev A, Volkov Y, Zholus A, Shayakhmetov RR, Zhebrak A, Minaeva LI, Zagribelnyy BA, Lee LH, Soll R, Madge D, Xing L, Guo T, Aspuru-Guzik A.

Nat Biotechnol. 2019 Sep;37(9):1038-1040. doi: 10.1038/s41587-019-0224-x. Epub 2019 Sep 2.

PMID:
31477924
5.

Immune profiles in primary squamous cell carcinoma of the head and neck.

Saloura V, Izumchenko E, Zuo Z, Bao R, Korzinkin M, Ozerov I, Zhavoronkov A, Sidransky D, Bedi A, Hoque MO, Koeppen H, Keck MK, Khattri A, London N, Kotlov N, Fatima A, Vougiouklakis T, Nakamura Y, Lingen M, Agrawal N, Savage PA, Kron S, Kline J, Kowanetz M, Seiwert TY.

Oral Oncol. 2019 Sep;96:77-88. doi: 10.1016/j.oraloncology.2019.06.032. Epub 2019 Jul 12.

6.

The Advent of Human Life Data Economics: (Trends in Molecular Medicine 25, 566-570; 2019).

Zhavoronkov A, Church G.

Trends Mol Med. 2019 Sep;25(9):817. doi: 10.1016/j.molmed.2019.07.005. Epub 2019 Aug 6. No abstract available.

PMID:
31399335
7.

Deep Aging Clocks: The Emergence of AI-Based Biomarkers of Aging and Longevity.

Zhavoronkov A, Mamoshina P.

Trends Pharmacol Sci. 2019 Aug;40(8):546-549. doi: 10.1016/j.tips.2019.05.004. Epub 2019 Jul 3.

8.

The Advent of Human Life Data Economics.

Zhavoronkov A, Church G.

Trends Mol Med. 2019 Jul;25(7):566-570. doi: 10.1016/j.molmed.2019.05.002. Epub 2019 Jun 27. Erratum in: Trends Mol Med. 2019 Sep;25(9):817.

PMID:
31257078
9.

Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity.

Moskalev AA, Shaposhnikov MV, Zemskaya NV, Koval LА, Schegoleva EV, Guvatova ZG, Krasnov GS, Solovev IA, Sheptyakov MA, Zhavoronkov A, Kudryavtseva AV.

Sci Rep. 2019 Jun 24;9(1):9151. doi: 10.1038/s41598-019-45714-x.

10.

Replicative and radiation-induced aging: a comparison of gene expression profiles.

Aliper AM, Bozdaganyan ME, Orekhov PS, Zhavoronkov A, Osipov AN.

Aging (Albany NY). 2019 Apr 19;11(8):2378-2387. doi: 10.18632/aging.101921.

11.

The Neuronal Overexpression of Gclc in Drosophila melanogaster Induces Life Extension With Longevity-Associated Transcriptomic Changes in the Thorax.

Moskalev A, Guvatova Z, Shaposhnikov M, Lashmanova E, Proshkina E, Koval L, Zhavoronkov A, Krasnov G, Kudryavtseva A.

Front Genet. 2019 Mar 5;10:149. doi: 10.3389/fgene.2019.00149. eCollection 2019.

12.

Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster.

Moskalev A, Proshkina E, Zhavoronkov A, Shaposhnikov M.

BMC Syst Biol. 2019 Mar 5;13(Suppl 1):16. doi: 10.1186/s12918-019-0687-x.

13.

PIM1 kinase promotes gallbladder cancer cell proliferation via inhibition of proline-rich Akt substrate of 40 kDa (PRAS40).

Subbannayya T, Leal-Rojas P, Zhavoronkov A, Ozerov IV, Korzinkin M, Babu N, Radhakrishnan A, Chavan S, Raja R, Pinto SM, Patil AH, Barbhuiya MA, Kumar P, Guerrero-Preston R, Navani S, Tiwari PK, Kumar RV, Prasad TSK, Roa JC, Pandey A, Sidransky D, Gowda H, Izumchenko E, Chatterjee A.

J Cell Commun Signal. 2019 Jun;13(2):163-177. doi: 10.1007/s12079-018-00503-5. Epub 2019 Jan 21.

14.

Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers.

Mamoshina P, Kochetov K, Cortese F, Kovalchuk A, Aliper A, Putin E, Scheibye-Knudsen M, Cantor CR, Skjodt NM, Kovalchuk O, Zhavoronkov A.

Sci Rep. 2019 Jan 15;9(1):142. doi: 10.1038/s41598-018-35704-w.

15.

Artificial intelligence for aging and longevity research: Recent advances and perspectives.

Zhavoronkov A, Mamoshina P, Vanhaelen Q, Scheibye-Knudsen M, Moskalev A, Aliper A.

Ageing Res Rev. 2019 Jan;49:49-66. doi: 10.1016/j.arr.2018.11.003. Epub 2018 Nov 22. Review.

16.

Aging and drug discovery.

Bakula D, Aliper AM, Mamoshina P, Petr MA, Teklu A, Baur JA, Campisi J, Ewald CY, Georgievskaya A, Gladyshev VN, Kovalchuk O, Lamming DW, Luijsterburg MS, Martín-Montalvo A, Maudsley S, Mkrtchyan GV, Moskalev A, Olshansky SJ, Ozerov IV, Pickett A, Ristow M, Zhavoronkov A, Scheibye-Knudsen M.

Aging (Albany NY). 2018 Nov 13;10(11):3079-3088. doi: 10.18632/aging.101646.

17.

PhotoAgeClock: deep learning algorithms for development of non-invasive visual biomarkers of aging.

Bobrov E, Georgievskaya A, Kiselev K, Sevastopolsky A, Zhavoronkov A, Gurov S, Rudakov K, Del Pilar Bonilla Tobar M, Jaspers S, Clemann S.

Aging (Albany NY). 2018 Nov 9;10(11):3249-3259. doi: 10.18632/aging.101629.

18.

Overexpression of CBS and CSE genes affects lifespan, stress resistance and locomotor activity in Drosophila melanogaster.

Shaposhnikov M, Proshkina E, Koval L, Zemskaya N, Zhavoronkov A, Moskalev A.

Aging (Albany NY). 2018 Nov 8;10(11):3260-3272. doi: 10.18632/aging.101630.

19.

Artificial Intelligence for Drug Discovery, Biomarker Development, and Generation of Novel Chemistry.

Zhavoronkov A.

Mol Pharm. 2018 Oct 1;15(10):4311-4313. doi: 10.1021/acs.molpharmaceut.8b00930. No abstract available.

PMID:
30269508
20.

Effects of N-acetyl-L-cysteine on lifespan, locomotor activity and stress-resistance of 3 Drosophila species with different lifespans.

Shaposhnikov MV, Zemskaya NV, Koval LA, Schegoleva EV, Zhavoronkov A, Moskalev AA.

Aging (Albany NY). 2018 Sep 20;10(9):2428-2458. doi: 10.18632/aging.101561.

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