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Peptide Nucleic Acids for MicroRNA Targeting.

Gambari R, Gasparello J, Fabbri E, Borgatti M, Tamanini A, Finotti A.

Methods Mol Biol. 2020;2105:199-215. doi: 10.1007/978-1-0716-0243-0_12.


High Levels of Apoptosis Are Induced in the Human Colon Cancer HT-29 Cell Line by Co-Administration of Sulforaphane and a Peptide Nucleic Acid Targeting miR-15b-5p.

Gasparello J, Gambari L, Papi C, Rozzi A, Manicardi A, Corradini R, Gambari R, Finotti A.

Nucleic Acid Ther. 2020 Feb 17. doi: 10.1089/nat.2019.0825. [Epub ahead of print]


Efficient Delivery of MicroRNA and AntimiRNA Molecules Using an Argininocalix[4]arene Macrocycle.

Gasparello J, Lomazzi M, Papi C, D'Aversa E, Sansone F, Casnati A, Donofrio G, Gambari R, Finotti A.

Mol Ther Nucleic Acids. 2019 Dec 6;18:748-763. doi: 10.1016/j.omtn.2019.09.029. Epub 2019 Oct 11.


Demonstrating specificity of bioactive peptide nucleic acids (PNAs) targeting microRNAs for practical laboratory classes of applied biochemistry and pharmacology.

Gasparello J, Papi C, Zurlo M, Corradini R, Gambari R, Finotti A.

PLoS One. 2019 Sep 11;14(9):e0221923. doi: 10.1371/journal.pone.0221923. eCollection 2019.


Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia.

Gemmo C, Breveglieri G, Marzaro G, Lampronti I, Cosenza LC, Gasparello J, Zuccato C, Fabbri E, Borgatti M, Chilin A, Finotti A, Gambari R.

Anal Bioanal Chem. 2019 Nov;411(29):7699-7707. doi: 10.1007/s00216-019-01987-9. Epub 2019 Jul 12.


Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters.

Breveglieri G, Salvatori F, Finotti A, Cosenza LC, Zuccato C, Bianchi N, Breda L, Rivella S, Bresciani A, Bisbocci M, Borgatti M, Gambari R.

Anal Bioanal Chem. 2019 Nov;411(29):7669-7680. doi: 10.1007/s00216-019-01959-z. Epub 2019 Jul 4.


Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells.

Milani R, Brognara E, Fabbri E, Manicardi A, Corradini R, Finotti A, Gasparello J, Borgatti M, Cosenza LC, Lampronti I, Dechecchi MC, Cabrini G, Gambari R.

Int J Oncol. 2019 Jul;55(1):59-68. doi: 10.3892/ijo.2019.4810. Epub 2019 May 23.


Altered erythroid-related miRNA levels as a possible novel biomarker for detection of autologous blood transfusion misuse in sport.

Gasparello J, Lamberti N, Papi C, Lampronti I, Cosenza LC, Fabbri E, Bianchi N, Zambon C, Dalla Corte F, Govoni M, Reverberi R, Manfredini F, Gambari R, Finotti A.

Transfusion. 2019 Aug;59(8):2709-2721. doi: 10.1111/trf.15383. Epub 2019 May 30.


Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene.

Gasparello J, Manicardi A, Casnati A, Corradini R, Gambari R, Finotti A, Sansone F.

Sci Rep. 2019 Feb 28;9(1):3036. doi: 10.1038/s41598-019-39211-4.


Enhancing the Expression of CFTR Using Antisense Molecules against MicroRNA miR-145-5p.

Finotti A, Gasparello J, Fabbri E, Tamanini A, Corradini R, Dechecchi MC, Cabrini G, Gambari R.

Am J Respir Crit Care Med. 2019 Jun 1;199(11):1443-1444. doi: 10.1164/rccm.201901-0019LE. No abstract available.


Non-invasive Prenatal Testing Using Fetal DNA.

Breveglieri G, D'Aversa E, Finotti A, Borgatti M.

Mol Diagn Ther. 2019 Apr;23(2):291-299. doi: 10.1007/s40291-019-00385-2. Review.


MicroRNAs and Long Non-coding RNAs in Genetic Diseases.

Finotti A, Fabbri E, Lampronti I, Gasparello J, Borgatti M, Gambari R.

Mol Diagn Ther. 2019 Apr;23(2):155-171. doi: 10.1007/s40291-018-0380-6. Review.


Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma.

Chung PY, Lam PL, Zhou YY, Gasparello J, Finotti A, Chilin A, Marzaro G, Gambari R, Bian ZX, Kwok WM, Wong WY, Wang X, Lam AK, Chan AS, Li X, Ma JY, Chui CH, Lam KH, Tang JC.

Cells. 2018 Oct 22;7(10). pii: E177. doi: 10.3390/cells7100177.


Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review).

Finotti A, Allegretti M, Gasparello J, Giacomini P, Spandidos DA, Spoto G, Gambari R.

Int J Oncol. 2018 Oct;53(4):1395-1434. doi: 10.3892/ijo.2018.4516. Epub 2018 Aug 6. Review.


Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA).

Gasparello J, Allegretti M, Tremante E, Fabbri E, Amoreo CA, Romania P, Melucci E, Messana K, Borgatti M, Giacomini P, Gambari R, Finotti A.

J Exp Clin Cancer Res. 2018 Jun 26;37(1):124. doi: 10.1186/s13046-018-0788-1.


UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation.

Salvatori F, Pappadà M, Breveglieri G, D'Aversa E, Finotti A, Lampronti I, Gambari R, Borgatti M.

BMC Biotechnol. 2018 May 15;18(1):28. doi: 10.1186/s12896-018-0435-0.


Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports.

Lamberti N, Finotti A, Gasparello J, Lampronti I, Zambon C, Cosenza LC, Fabbri E, Bianchi N, Dalla Corte F, Govoni M, Reverberi R, Gambari R, Manfredini F.

Intern Emerg Med. 2018 Jun;13(4):517-526. doi: 10.1007/s11739-018-1837-7. Epub 2018 Mar 23.


A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells.

Fabbri E, Tamanini A, Jakova T, Gasparello J, Manicardi A, Corradini R, Sabbioni G, Finotti A, Borgatti M, Lampronti I, Munari S, Dechecchi MC, Cabrini G, Gambari R.

Molecules. 2017 Dec 29;23(1). pii: E71. doi: 10.3390/molecules23010071.


PCR detection of segmented filamentous bacteria in the terminal ileum of patients with ulcerative colitis.

Finotti A, Gasparello J, Lampronti I, Cosenza LC, Maconi G, Matarese V, Gentili V, Di Luca D, Gambari R, Caselli M.

BMJ Open Gastroenterol. 2017 Dec 4;4(1):e000172. doi: 10.1136/bmjgast-2017-000172. eCollection 2017.


BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression.

Gasparello J, Fabbri E, Bianchi N, Breveglieri G, Zuccato C, Borgatti M, Gambari R, Finotti A.

Int J Mol Sci. 2017 Nov 26;18(12). pii: E2530. doi: 10.3390/ijms18122530.

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