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Items: 1 to 20 of 62


N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells.

Zuhra K, Tomé CS, Masi L, Giardina G, Paulini G, Malagrinò F, Forte E, Vicente JB, Giuffrè A.

Cells. 2019 Aug 4;8(8). pii: E828. doi: 10.3390/cells8080828.


Hydrogen Sulfide Oxidation: Adaptive Changes in Mitochondria of SW480 Colorectal Cancer Cells upon Exposure to Hypoxia.

Malagrinò F, Zuhra K, Mascolo L, Mastronicola D, Vicente JB, Forte E, Giuffrè A.

Oxid Med Cell Longev. 2019 Jan 29;2019:8102936. doi: 10.1155/2019/8102936. eCollection 2019.


Screening Pyridine Derivatives against Human Hydrogen Sulfide-synthesizing Enzymes by Orthogonal Methods.

Zuhra K, Sousa PMF, Paulini G, Lemos AR, Kalme Z, Bisenieks I, Bisenieks E, Vigante B, Duburs G, Bandeiras TM, Saso L, Giuffrè A, Vicente JB.

Sci Rep. 2019 Jan 24;9(1):684. doi: 10.1038/s41598-018-36994-w.


Substrate-induced conformational change in cytochrome P450 OleP.

Parisi G, Montemiglio LC, Giuffrè A, Macone A, Scaglione A, Cerutti G, Exertier C, Savino C, Vallone B.

FASEB J. 2019 Feb;33(2):1787-1800. doi: 10.1096/fj.201800450RR. Epub 2018 Sep 12.


Hydrogen Sulfide Biochemistry and Interplay with Other Gaseous Mediators in Mammalian Physiology.

Giuffrè A, Vicente JB.

Oxid Med Cell Longev. 2018 Jun 27;2018:6290931. doi: 10.1155/2018/6290931. eCollection 2018. Review.


The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity.

Falvo E, Malagrinò F, Arcovito A, Fazi F, Colotti G, Tremante E, Di Micco P, Braca A, Opri R, Giuffrè A, Fracasso G, Ceci P.

J Control Release. 2018 Apr 10;275:177-185. doi: 10.1016/j.jconrel.2018.02.025. Epub 2018 Feb 20.


Nitrosative stress defences of the enterohepatic pathogenic bacterium Helicobacter pullorum.

Parente MR, Forte E, Falabella M, Boneca IG, Teixeira M, Giuffrè A, Saraiva LM.

Sci Rep. 2017 Aug 30;7(1):9909. doi: 10.1038/s41598-017-10375-1.


Cytochrome bd and Gaseous Ligands in Bacterial Physiology.

Forte E, Borisov VB, Vicente JB, Giuffrè A.

Adv Microb Physiol. 2017;71:171-234. doi: 10.1016/bs.ampbs.2017.05.002. Epub 2017 Jul 10. Review.


A Clinically Relevant Variant of the Human Hydrogen Sulfide-Synthesizing Enzyme Cystathionine β-Synthase: Increased CO Reactivity as a Novel Molecular Mechanism of Pathogenicity?

Vicente JB, Colaço HG, Malagrinò F, Santo PE, Gutierres A, Bandeiras TM, Leandro P, Brito JA, Giuffrè A.

Oxid Med Cell Longev. 2017;2017:8940321. doi: 10.1155/2017/8940321. Epub 2017 Mar 22.


Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine β-synthase.

Vicente JB, Malagrinò F, Arese M, Forte E, Sarti P, Giuffrè A.

Biochim Biophys Acta. 2016 Aug;1857(8):1127-1138. doi: 10.1016/j.bbabio.2016.03.030. Epub 2016 Mar 31. Review.


The Terminal Oxidase Cytochrome bd Promotes Sulfide-resistant Bacterial Respiration and Growth.

Forte E, Borisov VB, Falabella M, Colaço HG, Tinajero-Trejo M, Poole RK, Vicente JB, Sarti P, Giuffrè A.

Sci Rep. 2016 Mar 31;6:23788. doi: 10.1038/srep23788.


Evidence for Detrimental Cross Interactions between Reactive Oxygen and Nitrogen Species in Leber's Hereditary Optic Neuropathy Cells.

Falabella M, Forte E, Magnifico MC, Santini P, Arese M, Giuffrè A, Radić K, Chessa L, Coarelli G, Buscarinu MC, Mechelli R, Salvetti M, Sarti P.

Oxid Med Cell Longev. 2016;2016:3187560. doi: 10.1155/2016/3187560. Epub 2015 Dec 31.


Antioxidant defence systems in the protozoan pathogen Giardia intestinalis.

Mastronicola D, Falabella M, Forte E, Testa F, Sarti P, Giuffrè A.

Mol Biochem Parasitol. 2016 Mar-Apr;206(1-2):56-66. doi: 10.1016/j.molbiopara.2015.12.002. Epub 2015 Dec 7. Review.


S-Adenosyl-l-methionine Modulates CO and NO• Binding to the Human H2S-generating Enzyme Cystathionine β-Synthase.

Vicente JB, Colaço HG, Sarti P, Leandro P, Giuffrè A.

J Biol Chem. 2016 Jan 8;291(2):572-81. doi: 10.1074/jbc.M115.681221. Epub 2015 Nov 18.


Superoxide reductase from Giardia intestinalis: structural characterization of the first SOR from a eukaryotic organism shows an iron centre that is highly sensitive to photoreduction.

Sousa CM, Carpentier P, Matias PM, Testa F, Pinho F, Sarti P, Giuffrè A, Bandeiras TM, Romão CV.

Acta Crystallogr D Biol Crystallogr. 2015 Nov;71(Pt 11):2236-47. doi: 10.1107/S1399004715015825. Epub 2015 Oct 31.


Antigiardial activity of novel triazolyl-quinolone-based chalcone derivatives: when oxygen makes the difference.

Bahadur V, Mastronicola D, Singh AK, Tiwari HK, Pucillo LP, Sarti P, Singh BK, Giuffrè A.

Front Microbiol. 2015 Apr 8;6:256. doi: 10.3389/fmicb.2015.00256. eCollection 2015.


Cytochrome bd from Escherichia coli catalyzes peroxynitrite decomposition.

Borisov VB, Forte E, Siletsky SA, Sarti P, Giuffrè A.

Biochim Biophys Acta. 2015 Feb;1847(2):182-188. doi: 10.1016/j.bbabio.2014.10.006. Epub 2014 Oct 29.


Flavodiiron oxygen reductase from Entamoeba histolytica: modulation of substrate preference by tyrosine 271 and lysine 53.

Gonçalves VL, Vicente JB, Pinto L, Romão CV, Frazão C, Sarti P, Giuffrè A, Teixeira M.

J Biol Chem. 2014 Oct 10;289(41):28260-70. doi: 10.1074/jbc.M114.579086. Epub 2014 Aug 23.


NO* binds human cystathionine β-synthase quickly and tightly.

Vicente JB, Colaço HG, Mendes MI, Sarti P, Leandro P, Giuffrè A.

J Biol Chem. 2014 Mar 21;289(12):8579-87. doi: 10.1074/jbc.M113.507533. Epub 2014 Feb 10.


Cytochrome bd oxidase and bacterial tolerance to oxidative and nitrosative stress.

Giuffrè A, Borisov VB, Arese M, Sarti P, Forte E.

Biochim Biophys Acta. 2014 Jul;1837(7):1178-87. doi: 10.1016/j.bbabio.2014.01.016. Epub 2014 Jan 31. Review.

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