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Items: 1 to 20 of 350

1.

Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase.

Oeckl P, Weydt P, Steinacker P, Anderl-Straub S, Nordin F, Volk AE, Diehl-Schmid J, Andersen PM, Kornhuber J, Danek A, Fassbender K, Fliessbach K; German Consortium for Frontotemporal Lobar Degeneration, Jahn H, Lauer M, Müller K, Knehr A, Prudlo J, Schneider A, Thal DR, Yilmazer-Hanke D, Weishaupt JH, Ludolph AC, Otto M.

J Neurol Neurosurg Psychiatry. 2018 Sep 17. pii: jnnp-2018-318868. doi: 10.1136/jnnp-2018-318868. [Epub ahead of print]

PMID:
30224549
2.

Current knowledge and recent insights into the genetic basis of amyotrophic lateral sclerosis.

Volk AE, Weishaupt JH, Andersen PM, Ludolph AC, Kubisch C.

Med Genet. 2018;30(2):252-258. doi: 10.1007/s11825-018-0185-3. Epub 2018 Jul 13. Review.

3.

Serum neurofilament light chain in behavioral variant frontotemporal dementia.

Steinacker P, Anderl-Straub S, Diehl-Schmid J, Semler E, Uttner I, von Arnim CAF, Barthel H, Danek A, Fassbender K, Fliessbach K, Foerstl H, Grimmer T, Huppertz HJ, Jahn H, Kassubek J, Kornhuber J, Landwehrmeyer B, Lauer M, Maler JM, Mayer B, Oeckl P, Prudlo J, Schneider A, Volk AE, Wiltfang J, Schroeter ML, Ludolph AC, Otto M; FTLDc study group.

Neurology. 2018 Sep 12. pii: 10.1212/WNL.0000000000006318. doi: 10.1212/WNL.0000000000006318. [Epub ahead of print]

PMID:
30209235
4.

Screening for Cognitive Function in Complete Immobility Using Brain-Machine Interfaces: A Proof of Principle Study.

Lulé D, Hörner K, Vazquez C, Aho-Özhan H, Keller J, Gorges M, Uttner I, Ludolph AC.

Front Neurosci. 2018 Aug 15;12:517. doi: 10.3389/fnins.2018.00517. eCollection 2018.

5.

Acute DWI Reductions In Patients After Single Epileptic Seizures - More Common Than Assumed.

Hübers A, Thoma K, Schocke M, Fauser S, Ludolph AC, Kassubek J, Pinkhardt EH.

Front Neurol. 2018 Jul 25;9:550. doi: 10.3389/fneur.2018.00550. eCollection 2018.

6.

Stage-dependent remodeling of projections to motor cortex in ALS mouse model revealed by a new variant retrograde-AAV9.

Commisso B, Ding L, Varadi K, Gorges M, Bayer D, Boeckers TM, Ludolph AC, Kassubek J, Müller OJ, Roselli F.

Elife. 2018 Aug 23;7. pii: e36892. doi: 10.7554/eLife.36892.

7.

Retinoids and Amyotrophic Lateral Sclerosis-Reply.

Nagel G, Rothenbacher D, Ludolph AC.

JAMA Neurol. 2018 Sep 1;75(9):1153-1154. doi: 10.1001/jamaneurol.2018.2257. No abstract available.

PMID:
30105395
8.

Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS.

Helferich AM, Brockmann SJ, Reinders J, Deshpande D, Holzmann K, Brenner D, Andersen PM, Petri S, Thal DR, Michaelis J, Otto M, Just S, Ludolph AC, Danzer KM, Freischmidt A, Weishaupt JH.

Cell Mol Life Sci. 2018 Jul 20. doi: 10.1007/s00018-018-2873-1. [Epub ahead of print]

PMID:
30030593
9.

Parvalbumin Interneurons Shape Neuronal Vulnerability in Blunt TBI.

Chandrasekar A, Olde Heuvel F, Tar L, Hagenston AM, Palmer A, Linkus B, Ludolph AC, Huber-Lang M, Boeckers T, Bading H, Roselli F.

Cereb Cortex. 2018 Jun 30. doi: 10.1093/cercor/bhy139. [Epub ahead of print]

PMID:
29982364
10.

Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial.

Ludolph AC, Schuster J, Dorst J, Dupuis L, Dreyhaupt J, Weishaupt JH, Kassubek J, Weiland U, Petri S, Meyer T, Grosskreutz J, Schrank B, Boentert M, Emmer A, Hermann A, Zeller D, Prudlo J, Winkler AS, Grehl T, Heneka MT, Wollebæk Johannesen S, Göricke B; RAS-ALS Study Group.

Lancet Neurol. 2018 Aug;17(8):681-688. doi: 10.1016/S1474-4422(18)30176-5. Epub 2018 Jun 19.

PMID:
29934198
11.

NEK1 loss-of-function mutation induces DNA damage accumulation in ALS patient-derived motoneurons.

Higelin J, Catanese A, Semelink-Sedlacek LL, Oeztuerk S, Lutz AK, Bausinger J, Barbi G, Speit G, Andersen PM, Ludolph AC, Demestre M, Boeckers TM.

Stem Cell Res. 2018 Jul;30:150-162. doi: 10.1016/j.scr.2018.06.005. Epub 2018 Jun 12.

12.

Antisense oligonucleotides in neurological disorders.

Wurster CD, Ludolph AC.

Ther Adv Neurol Disord. 2018 May 23;11:1756286418776932. doi: 10.1177/1756286418776932. eCollection 2018. Review.

13.

Identical patterns of cortico-efferent tract involvement in primary lateral sclerosis and amyotrophic lateral sclerosis: A tract of interest-based MRI study.

Müller HP, Gorges M, Kassubek R, Dorst J, Ludolph AC, Kassubek J.

Neuroimage Clin. 2018 Mar 15;18:762-769. doi: 10.1016/j.nicl.2018.03.018. eCollection 2018.

14.

Therapeutic decisions in ALS patients: cross-cultural differences and clinical implications.

Andersen PM, Kuzma-Kozakiewicz M, Keller J, Aho-Oezhan HEA, Ciecwierska K, Szejko N, Vázquez C, Böhm S, Badura-Lotter G, Meyer T, Petri S, Linse K, Hermann A, Semb O, Stenberg E, Nackberg S, Dorst J, Uttner I, Häggström AC, Ludolph AC, Lulé D.

J Neurol. 2018 Jul;265(7):1600-1606. doi: 10.1007/s00415-018-8861-4. Epub 2018 May 4.

PMID:
29728768
15.

A language-based sum score for the course and therapeutic intervention in primary progressive aphasia.

Semler E, Anderl-Straub S, Uttner I, Diehl-Schmid J, Danek A, Einsiedler B, Fassbender K, Fliessbach K, Huppertz HJ, Jahn H, Kornhuber J, Landwehrmeyer B, Lauer M, Muche R, Prudlo J, Schneider A, Schroeter ML, Ludolph AC, Otto M; FTLD consortium.

Alzheimers Res Ther. 2018 Apr 25;10(1):41. doi: 10.1186/s13195-018-0345-3.

16.

Comprehensive analysis of the mutation spectrum in 301 German ALS families.

Müller K, Brenner D, Weydt P, Meyer T, Grehl T, Petri S, Grosskreutz J, Schuster J, Volk AE, Borck G, Kubisch C, Klopstock T, Zeller D, Jablonka S, Sendtner M, Klebe S, Knehr A, Günther K, Weis J, Claeys KG, Schrank B, Sperfeld AD, Hübers A, Otto M, Dorst J, Meitinger T, Strom TM, Andersen PM, Ludolph AC, Weishaupt JH; German ALS network MND-NET.

J Neurol Neurosurg Psychiatry. 2018 Aug;89(8):817-827. doi: 10.1136/jnnp-2017-317611. Epub 2018 Apr 12.

PMID:
29650794
17.

Chromogranin A levels in the cerebrospinal fluid of patients with amyotrophic lateral sclerosis.

Verde F, Steinacker P, Oeckl P, Weishaupt JH, Rosenbohm A, Silani V, Ludolph AC, Otto M.

Neurobiol Aging. 2018 Jul;67:21-22. doi: 10.1016/j.neurobiolaging.2018.02.017. Epub 2018 Feb 27.

PMID:
29609078
18.

Alpha-synuclein is present in dental calculus but not altered in Parkinson's disease patients in comparison to controls.

Schmid S, Goldberg-Bockhorn E, Schwarz S, Rotter N, Kassubek J, Del Tredici K, Pinkhardt E, Otto M, Ludolph AC, Oeckl P.

J Neurol. 2018 Jun;265(6):1334-1337. doi: 10.1007/s00415-018-8847-2. Epub 2018 Mar 29.

PMID:
29600388
19.

Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model.

Westeneng HJ, Debray TPA, Visser AE, van Eijk RPA, Rooney JPK, Calvo A, Martin S, McDermott CJ, Thompson AG, Pinto S, Kobeleva X, Rosenbohm A, Stubendorff B, Sommer H, Middelkoop BM, Dekker AM, van Vugt JJFA, van Rheenen W, Vajda A, Heverin M, Kazoka M, Hollinger H, Gromicho M, Körner S, Ringer TM, Rödiger A, Gunkel A, Shaw CE, Bredenoord AL, van Es MA, Corcia P, Couratier P, Weber M, Grosskreutz J, Ludolph AC, Petri S, de Carvalho M, Van Damme P, Talbot K, Turner MR, Shaw PJ, Al-Chalabi A, Chiò A, Hardiman O, Moons KGM, Veldink JH, van den Berg LH.

Lancet Neurol. 2018 May;17(5):423-433. doi: 10.1016/S1474-4422(18)30089-9. Epub 2018 Mar 26.

20.

Nusinersen for spinal muscular atrophy.

Wurster CD, Ludolph AC.

Ther Adv Neurol Disord. 2018 Mar 13;11:1756285618754459. doi: 10.1177/1756285618754459. eCollection 2018. No abstract available.

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