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Items: 1 to 20 of 123

1.

Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic Perspective.

Ong MS, Deng S, Halim CE, Cai W, Tan TZ, Huang RY, Sethi G, Hooi SC, Kumar AP, Yap CT.

Cancers (Basel). 2020 Jan 18;12(1). pii: E238. doi: 10.3390/cancers12010238. Review.

2.

The IκB Kinase Inhibitor ACHP Targets the STAT3 Signaling Pathway in Human Non-Small Cell Lung Carcinoma Cells.

Lee JH, Mohan CD, Basappa S, Rangappa S, Chinnathambi A, Alahmadi TA, Alharbi SA, Kumar AP, Sethi G, Ahn KS, Rangappa KS.

Biomolecules. 2019 Dec 13;9(12). pii: E875. doi: 10.3390/biom9120875.

3.

Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy.

Khattar E, Maung KZY, Chew CL, Ghosh A, Mok MMH, Lee P, Zhang J, Chor WHJ, Cildir G, Wang CQ, Mohd-Ismail NK, Chin DWL, Lee SC, Yang H, Shin YJ, Nam DH, Chen L, Kumar AP, Deng LW, Ikawa M, Gunaratne J, Osato M, Tergaonkar V.

Nat Commun. 2019 Dec 13;10(1):5349. doi: 10.1038/s41467-019-13082-9.

4.

Pharmacological Inhibition of TFF3 Enhances Sensitivity of CMS4 Colorectal Carcinoma to 5-Fluorouracil through Inhibition of p44/42 MAPK.

Chen RM, Chiou YS, Chong QY, Poh HM, Tan TZ, Zhang MY, Ma L, Zhu T, Pandey V, Basappa, Kumar AP, Lobie PE.

Int J Mol Sci. 2019 Dec 9;20(24). pii: E6215. doi: 10.3390/ijms20246215.

5.

Peruvoside targets apoptosis and autophagy through MAPK Wnt/β-catenin and PI3K/AKT/mTOR signaling pathways in human cancers.

Reddy D, Kumavath R, Tan TZ, Ampasala DR, Kumar AP.

Life Sci. 2020 Jan 15;241:117147. doi: 10.1016/j.lfs.2019.117147. Epub 2019 Dec 9.

PMID:
31830480
6.

TIPE2 Induced the Proliferation, Survival, and Migration of Lung Cancer Cells Through Modulation of Akt/mTOR/NF-κB Signaling Cascade.

Bordoloi D, Banik K, Padmavathi G, Vikkurthi R, Harsha C, Roy NK, Singh AK, Monisha J, Wang H, Kumar AP, Kunnumakkara AB.

Biomolecules. 2019 Dec 6;9(12). pii: E836. doi: 10.3390/biom9120836.

7.

An Investigation on the Therapeutic Potential of Butein, A Tretrahydroxychalcone Against Human Oral Squamous Cell Carcinoma.

Bordoloi D, Monisha J, Roy NK, Padmavathi G, Banik K, Harsha C, Wang H, Kumar AP, Arfuso F, Kunnumakkara AB.

Asian Pac J Cancer Prev. 2019 Nov 1;20(11):3437-3446. doi: 10.31557/APJCP.2019.20.11.3437.

8.

Author Correction: c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression.

Sim WJ, Iyengar PV, Lama D, Lui SKL, Ng HC, Haviv-Shapira L, Domany E, Kappei D, Tan TZ, Saei A, Jaynes PW, Verma CS, Kumar AP, Rouanne M, Ha HK, Radulescu C, Ten Dijke P, Eichhorn PJA, Thiery JP.

Nat Commun. 2019 Nov 8;10(1):5148. doi: 10.1038/s41467-019-13095-4.

9.

Inhibition of TFF3 Enhances Sensitivity-and Overcomes Acquired Resistance-to Doxorubicin in Estrogen Receptor-Positive Mammary Carcinoma.

Poh HM, Chiou YS, Chong QY, Chen RM, Rangappa KS, Ma L, Zhu T, Kumar AP, Pandey V; Basappa, Lee SC, Lobie PE.

Cancers (Basel). 2019 Oct 10;11(10). pii: E1528. doi: 10.3390/cancers11101528.

10.

Autophagy Modulators: Mechanistic Aspects and Drug Delivery Systems.

Tavakol S, Ashrafizadeh M, Deng S, Azarian M, Abdoli A, Motavaf M, Poormoghadam D, Khanbabaei H, Afshar EG, Mandegary A, Pardakhty A, Yap CT, Mohammadinejad R, Kumar AP.

Biomolecules. 2019 Sep 25;9(10). pii: E530. doi: 10.3390/biom9100530. Review.

11.

c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression.

Sim WJ, Iyengar PV, Lama D, Lui SKL, Ng HC, Haviv-Shapira L, Domany E, Kappei D, Tan TZ, Saei A, Jaynes PW, Verma CS, Kumar AP, Rouanne M, Ha HK, Radulescu C, Ten Dijke P, Eichhorn PJA, Thiery JP.

Nat Commun. 2019 Sep 25;10(1):4349. doi: 10.1038/s41467-019-12241-2. Erratum in: Nat Commun. 2019 Nov 8;10(1):5148.

12.

Anti-cancer effects of oxymatrine are mediated through multiple molecular mechanism(s) in tumor models.

Halim CE, Xinjing SL, Fan L, Bailey Vitarbo J, Arfuso F, Tan CH, Narula AS, Kumar AP, Sethi G, Ahn KS.

Pharmacol Res. 2019 Sep;147:104327. doi: 10.1016/j.phrs.2019.104327. Epub 2019 Jul 5. Review.

PMID:
31283981
13.

Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma.

Roy NK, Monisha J, Padmavathi G, Lalhruaitluanga H, Kumar NS, Singh AK, Bordoloi D, Baruah MN, Ahmed GN, Longkumar I, Arfuso F, Kumar AP, Kunnumakkara AB.

Biomolecules. 2019 Jun 27;9(7). pii: E253. doi: 10.3390/biom9070253.

14.

Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential.

Varughese RS, Lam WS, Marican AABH, Viganeshwari SH, Bhave AS, Syn NL, Wang J, Wong AL, Kumar AP, Lobie PE, Lee SC, Sethi G, Goh BC, Wang L.

Cancer. 2019 Jun 1;125(11):1789-1798. doi: 10.1002/cncr.32069. Epub 2019 Apr 1. Review.

PMID:
30933320
15.

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases.

Mishra S, Verma SS, Rai V, Awasthee N, Chava S, Hui KM, Kumar AP, Challagundla KB, Sethi G, Gupta SC.

Cell Mol Life Sci. 2019 May;76(10):1947-1966. doi: 10.1007/s00018-019-03053-0. Epub 2019 Mar 16. Review.

PMID:
30879091
16.

FBXW7 in Cancer: What Has Been Unraveled Thus Far?

Sailo BL, Banik K, Girisa S, Bordoloi D, Fan L, Halim CE, Wang H, Kumar AP, Zheng D, Mao X, Sethi G, Kunnumakkara AB.

Cancers (Basel). 2019 Feb 19;11(2). pii: E246. doi: 10.3390/cancers11020246. Review.

17.

Targeting autophagy using natural compounds for cancer prevention and therapy.

Deng S, Shanmugam MK, Kumar AP, Yap CT, Sethi G, Bishayee A.

Cancer. 2019 Apr 15;125(8):1228-1246. doi: 10.1002/cncr.31978. Epub 2019 Feb 12. Review.

PMID:
30748003
18.

The expanding roles of long non-coding RNAs in the regulation of cancer stem cells.

Ma Z, Wang YY, Xin HW, Wang L, Arfuso F, Dharmarajan A, Kumar AP, Wang H, Tang FR, Warrier S, Tergaonkar V, Sethi G.

Int J Biochem Cell Biol. 2019 Mar;108:17-20. doi: 10.1016/j.biocel.2019.01.003. Epub 2019 Jan 7. Review.

PMID:
30630112
19.

Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma.

Bhuvanalakshmi G, Gamit N, Patil M, Arfuso F, Sethi G, Dharmarajan A, Kumar AP, Warrier S.

Cancers (Basel). 2018 Dec 27;11(1). pii: E25. doi: 10.3390/cancers11010025.

20.

Thymoquinone Inhibits Bone Metastasis of Breast Cancer Cells Through Abrogation of the CXCR4 Signaling Axis.

Shanmugam MK, Ahn KS, Hsu A, Woo CC, Yuan Y, Tan KHB, Chinnathambi A, Alahmadi TA, Alharbi SA, Koh APF, Arfuso F, Huang RY, Lim LHK, Sethi G, Kumar AP.

Front Pharmacol. 2018 Dec 4;9:1294. doi: 10.3389/fphar.2018.01294. eCollection 2018.

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