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Items: 1 to 20 of 54


Proteome-wide signatures of function in highly diverged intrinsically disordered regions.

Zarin T, Strome B, Nguyen Ba AN, Alberti S, Forman-Kay JD, Moses AM.

Elife. 2019 Jul 2;8. pii: e46883. doi: 10.7554/eLife.46883.


YeastSpotter: Accurate and parameter-free web segmentation for microscopy images of yeast cells.

Lu AX, Zarin T, Hsu IS, Moses AM.

Bioinformatics. 2019 May 16. pii: btz402. doi: 10.1093/bioinformatics/btz402. [Epub ahead of print]


Variational Infinite Heterogeneous Mixture Model for Semi-supervised Clustering of Heart Enhancers.

Mehdi TF, Singh G, Mitchell JA, Moses AM.

Bioinformatics. 2019 Feb 7. doi: 10.1093/bioinformatics/btz064. [Epub ahead of print]


A Noisy Analog-to-Digital Converter Connects Cytosolic Calcium Bursts to Transcription Factor Nuclear Localization Pulses in Yeast.

Hsu IS, Strome B, Plotnikov S, Moses AM.

G3 (Bethesda). 2019 Feb 7;9(2):561-570. doi: 10.1534/g3.118.200841.


Short linear motifs in intrinsically disordered regions modulate HOG signaling capacity.

Strome B, Hsu IS, Li Cheong Man M, Zarin T, Nguyen Ba A, Moses AM.

BMC Syst Biol. 2018 Jul 3;12(1):75. doi: 10.1186/s12918-018-0597-3.


Integrating images from multiple microscopy screens reveals diverse patterns of change in the subcellular localization of proteins.

Lu AX, Chong YT, Hsu IS, Strome B, Handfield LF, Kraus O, Andrews BJ, Moses AM.

Elife. 2018 Apr 5;7. pii: e31872. doi: 10.7554/eLife.31872.


NoLogo: a new statistical model highlights the diversity and suggests new classes of Crm1-dependent nuclear export signals.

Liku ME, Legere EA, Moses AM.

BMC Bioinformatics. 2018 Feb 27;19(1):65. doi: 10.1186/s12859-018-2076-7.


Parallel reorganization of protein function in the spindle checkpoint pathway through evolutionary paths in the fitness landscape that appear neutral in laboratory experiments.

Nguyen Ba AN, Strome B, Osman S, Legere EA, Zarin T, Moses AM.

PLoS Genet. 2017 Apr 14;13(4):e1006735. doi: 10.1371/journal.pgen.1006735. eCollection 2017 Apr.


Selection maintains signaling function of a highly diverged intrinsically disordered region.

Zarin T, Tsai CN, Nguyen Ba AN, Moses AM.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1450-E1459. doi: 10.1073/pnas.1614787114. Epub 2017 Feb 6.


Functional Analysis of Kinases and Transcription Factors in Saccharomyces cerevisiae Using an Integrated Overexpression Library.

Youn JY, Friesen H, Nguyen Ba AN, Liang W, Messier V, Cox MJ, Moses AM, Andrews B.

G3 (Bethesda). 2017 Mar 10;7(3):911-921. doi: 10.1534/g3.116.038471.


Introduction of Premature Stop Codons as an Evolutionary Strategy To Rescue Signaling Network Function.

Kompella PS, Moses AM, Peisajovich SG.

ACS Synth Biol. 2017 Mar 17;6(3):446-454. doi: 10.1021/acssynbio.6b00142. Epub 2016 Dec 27.


An Unsupervised kNN Method to Systematically Detect Changes in Protein Localization in High-Throughput Microscopy Images.

Lu AX, Moses AM.

PLoS One. 2016 Jul 21;11(7):e0158712. doi: 10.1371/journal.pone.0158712. eCollection 2016.


Decreased Transcription Factor Binding Levels Nearby Primate Pseudogenes Suggest Regulatory Degeneration.

Douglas GM, Wilson MD, Moses AM.

Mol Biol Evol. 2016 Jun;33(6):1478-85. doi: 10.1093/molbev/msw030. Epub 2016 Feb 16.


Short linear motifs - ex nihilo evolution of protein regulation.

Davey NE, Cyert MS, Moses AM.

Cell Commun Signal. 2015 Nov 21;13:43. doi: 10.1186/s12964-015-0120-z. Review.


Computational learning on specificity-determining residue-nucleotide interactions.

Wong KC, Li Y, Peng C, Moses AM, Zhang Z.

Nucleic Acids Res. 2015 Dec 2;43(21):10180-9. doi: 10.1093/nar/gkv1134. Epub 2015 Nov 2.


Polymorphism Analysis Reveals Reduced Negative Selection and Elevated Rate of Insertions and Deletions in Intrinsically Disordered Protein Regions.

Khan T, Douglas GM, Patel P, Nguyen Ba AN, Moses AM.

Genome Biol Evol. 2015 Jun 4;7(6):1815-26. doi: 10.1093/gbe/evv105.


The Structure of an NDR/LATS Kinase-Mob Complex Reveals a Novel Kinase-Coactivator System and Substrate Docking Mechanism.

Gógl G, Schneider KD, Yeh BJ, Alam N, Nguyen Ba AN, Moses AM, Hetényi C, Reményi A, Weiss EL.

PLoS Biol. 2015 May 12;13(5):e1002146. doi: 10.1371/journal.pbio.1002146. eCollection 2015 May.


Detecting functional divergence after gene duplication through evolutionary changes in posttranslational regulatory sequences.

Nguyen Ba AN, Strome B, Hua JJ, Desmond J, Gagnon-Arsenault I, Weiss EL, Landry CR, Moses AM.

PLoS Comput Biol. 2014 Dec 4;10(12):e1003977. doi: 10.1371/journal.pcbi.1003977. eCollection 2014 Dec.


Local statistics allow quantification of cell-to-cell variability from high-throughput microscope images.

Handfield LF, Strome B, Chong YT, Moses AM.

Bioinformatics. 2015 Mar 15;31(6):940-7. doi: 10.1093/bioinformatics/btu759. Epub 2014 Nov 14.


Turnover of protein phosphorylation evolving under stabilizing selection.

Landry CR, Freschi L, Zarin T, Moses AM.

Front Genet. 2014 Jul 23;5:245. doi: 10.3389/fgene.2014.00245. eCollection 2014. Review.

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