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Items: 1 to 20 of 23

1.

Rational Design and Synthesis of Diverse Pyrimidine Molecules Bearing Sulfonamide Moiety as Novel ERK Inhibitors.

Halawa AH, Eskandrani AA, Elgammal WE, Hassan SM, Hassan AH, Ebrahim HY, Mehany ABM, El-Agrody AM, Okasha RM.

Int J Mol Sci. 2019 Nov 8;20(22). pii: E5592. doi: 10.3390/ijms20225592.

2.

Microwave synthesis of novel halogenated β-enaminonitriles linked 9-bromo-1H-benzo[f]chromene moieties: Induces cell cycle arrest and apoptosis in human cancer cells via dual inhibition of topoisomerase I and II.

Fouda AM, Assiri MA, Mora A, Ali TE, Afifi TH, El-Agrody AM.

Bioorg Chem. 2019 Dec;93:103289. doi: 10.1016/j.bioorg.2019.103289. Epub 2019 Sep 20.

PMID:
31586716
3.

Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo[h]chromene.

Alblewi FF, Okasha RM, Hritani ZM, Mohamed HM, El-Nassag MAA, Halawa AH, Mora A, Fouda AM, Assiri MA, Al-Dies AM, Afifi TH, El-Agrody AM.

Bioorg Chem. 2019 Jun;87:560-571. doi: 10.1016/j.bioorg.2019.03.059. Epub 2019 Mar 22.

PMID:
30928878
4.

Design and Synthesis of Novel Heterocyclic-Based 4H-benzo[h]chromene Moieties: Targeting Antitumor Caspase 3/7 Activities and Cell Cycle Analysis.

Alblewi FF, Okasha RM, Eskandrani AA, Afifi TH, Mohamed HM, Halawa AH, Fouda AM, Al-Dies AM, Mora A, El-Agrody AM.

Molecules. 2019 Mar 18;24(6). pii: E1060. doi: 10.3390/molecules24061060.

5.

Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect.

Ahmed HEA, El-Nassag MAA, Hassan AH, Okasha RM, Ihmaid S, Fouda AM, Afifi TH, Aljuhani A, El-Agrody AM.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):1074-1088. doi: 10.1080/14756366.2018.1476503.

6.

Synthesis, biological activity and molecular modeling study of new Schiff bases incorporated with indole moiety.

Halawa AH, El-Gilil SMA, Bedair AH, Shaaban M, Frese M, Sewald N, Eliwa EM, El-Agrody AM.

Z Naturforsch C J Biosci. 2017 Oct 26;72(11-12):467-475. doi: 10.1515/znc-2017-0025.

PMID:
28525356
7.

Design of New Benzo[h]chromene Derivatives: Antitumor Activities and Structure-Activity Relationships of the 2,3-Positions and Fused Rings at the 2,3-Positions.

Okasha RM, Alblewi FF, Afifi TH, Naqvi A, Fouda AM, Al-Dies AM, El-Agrody AM.

Molecules. 2017 Mar 18;22(3). pii: E479. doi: 10.3390/molecules22030479.

8.

Synthesis, in-vitro cytotoxicity of 1H-benzo[f]chromene derivatives and structure-activity relationships of the 1-aryl group and 9-position.

Mohamed HM, Fouda AM, Khattab ESAEH, Agrody AME, Afifi TH.

Z Naturforsch C J Biosci. 2017 May 1;72(5-6):161-171. doi: 10.1515/znc-2016-0139.

PMID:
27831925
9.
10.

2-(4-Fluoro-benzyl-idene)propane-dinitrile: monoclinic polymorph.

El-Agrody AM, Al-Omar MA, Amr Ael-G, Ng SW, Tiekink ER.

Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 9;69(Pt 4):o515. doi: 10.1107/S1600536813006235. Print 2013 Apr 1.

11.

N'-[3-Cyano-4-(4-fluoro-phen-yl)-6-meth-oxy-4H-benzo[h]chromen-2-yl]-N,N-dimethyl-methanimidamide.

Al-Dies AA, Al-Omar MA, Amr Ael-G, El-Agrody AM, Ng SW, Tiekink ER.

Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 2;69(Pt 4):o482-3. doi: 10.1107/S1600536813005503. Print 2013 Apr 1.

12.

2-Amino-4-(4-bromo-phen-yl)-6-meth-oxy-4H-benzo[h]chromene-3-carbonitrile.

Al-Dies AA, El-Agrody AM, Al-Omar MA, Amr Ael-G, Ng SW, Tiekink ER.

Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 2;69(Pt 4):o480-1. doi: 10.1107/S1600536813005461. Print 2013 Apr 1.

13.

3-Amino-1-(4-fluoro-phen-yl)-7-meth-oxy-1H-benzo[f]chromene-2-carbonitrile.

Amr Ael-G, El-Agrody AM, Al-Omar MA, Ng SW, Tiekink ER.

Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 2;69(Pt 4):o478-9. doi: 10.1107/S1600536813005473. Print 2013 Apr 1.

14.

3-Amino-1-(4-fluoro-phen-yl)-8-meth-oxy-1H-benzo[f]chromene-2-carbonitrile.

El-Agrody AM, Al-Omar MA, Amr Ael-G, Ng SW, Tiekink ER.

Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 2;69(Pt 4):o476-7. doi: 10.1107/S160053681300545X. Print 2013 Apr 1.

15.

2-Amino-4-(4-chloro-phen-yl)-4H-chromeno[8,7-b]pyridine-3-carbonitrile.

Amr Ael-G, El-Agrody AM, Sabry NM, Ng SW, Tiekink ER.

Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 2;69(Pt 4):o462-3. doi: 10.1107/S1600536813005217. Print 2013 Apr 1.

16.

Ethyl 2-amino-4-(4-bromo-phen-yl)-6-meth-oxy-4H-benzo[h]chromene-3-carboxyl-ate.

El-Agrody AM, Fouda AM, Al-Omar MA, Amr Ael-G, Ng SW, Tiekink ER.

Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 1;69(Pt 3):o435-6. doi: 10.1107/S160053681300490X. Epub 2013 Feb 23.

17.

2-Amino-4-(4-fluoro-phen-yl)-6-meth-oxy-4H-benzo[h]chromene-3-carbonitrile.

Al-Dies AA, Amr AG, El-Agrody AM, Chia TS, Fun HK.

Acta Crystallogr Sect E Struct Rep Online. 2012 Jun 1;68(Pt 6):o1934-5. doi: 10.1107/S1600536812023021. Epub 2012 May 31.

18.

Ethyl 2-amino-4-(4-fluoro-phen-yl)-6-meth-oxy-4H-benzo[h]chromene-3-carboxyl-ate.

El-Agrody AM, Al-Omar MA, Amr AG, Chia TS, Fun HK.

Acta Crystallogr Sect E Struct Rep Online. 2012 Jun 1;68(Pt 6):o1803-4. doi: 10.1107/S1600536812021939. Epub 2012 May 19.

19.

Synthesis, reactions and antimicrobial activities of 8-ethoxycoumarin derivatives.

Mohamed HM, Abd El-Wahab AH, Ahmed KA, El-Agrody AM, Bedair AH, Eid FA, Khafagy MM.

Molecules. 2012 Jan 18;17(1):971-88. doi: 10.3390/molecules17010971.

20.

Synthesis and characterization of new diiodocoumarin derivatives with promising antimicrobial activities.

Mohamed HM, El-Wahab AH, El-Agrody AM, Bedair AH, Eid FA, Khafagy MM, Abd-El-Rehem KA.

Beilstein J Org Chem. 2011;7:1688-96. doi: 10.3762/bjoc.7.199. Epub 2011 Dec 19.

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