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Items: 1 to 20 of 46


Bioactive glycoalkaloides isolated from Solanum melongena fruit peels with potential anticancer properties against hepatocellular carcinoma cells.

Fekry MI, Ezzat SM, Salama MM, Alshehri OY, Al-Abd AM.

Sci Rep. 2019 Feb 11;9(1):1746. doi: 10.1038/s41598-018-36089-6.


Stimuli-Responsive Nano-Architecture Drug-Delivery Systems to Solid Tumor Micromilieu: Past, Present, and Future Perspectives.

El-Sawy HS, Al-Abd AM, Ahmed TA, El-Say KM, Torchilin VP.

ACS Nano. 2018 Nov 27;12(11):10636-10664. doi: 10.1021/acsnano.8b06104. Epub 2018 Oct 23.


Thymoquinone synergizes gemcitabine anti-breast cancer activity via modulating its apoptotic and autophagic activities.

Bashmail HA, Alamoudi AA, Noorwali A, Hegazy GA, AJabnoor G, Choudhry H, Al-Abd AM.

Sci Rep. 2018 Aug 3;8(1):11674. doi: 10.1038/s41598-018-30046-z.


Anticancer Profiling for Coumarins and Related O-Naphthoquinones from Mansonia gagei against Solid Tumor Cells In Vitro.

Baghdadi MA, Al-Abbasi FA, El-Halawany AM, Aseeri AH, Al-Abd AM.

Molecules. 2018 Apr 26;23(5). pii: E1020. doi: 10.3390/molecules23051020.


Anti-Helicobacter, Antitubercular and Cytotoxic Activities of Scalaranes from the Red Sea Sponge Hyrtios erectus.

Alahdal AM, Asfour HZ, Ahmed SA, Noor AO, Al-Abd AM, Elfaky MA, Elhady SS.

Molecules. 2018 Apr 23;23(4). pii: E978. doi: 10.3390/molecules23040978.


Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells.

Allam RM, Al-Abd AM, Khedr A, Sharaf OA, Nofal SM, Khalifa AE, Mosli HA, Abdel-Naim AB.

Toxicol Lett. 2018 Jul;291:77-85. doi: 10.1016/j.toxlet.2018.04.008. Epub 2018 Apr 11.


Rutin Isolated from Chrozophora tinctoria Enhances Bone Cell Proliferation and Ossification Markers.

Abdel-Naim AB, Alghamdi AA, Algandaby MM, Al-Abbasi FA, Al-Abd AM, Eid BG, Abdallah HM, El-Halawany AM.

Oxid Med Cell Longev. 2018 Feb 13;2018:5106469. doi: 10.1155/2018/5106469. eCollection 2018.


Enhancing the Therapeutic Efficacy of Tamoxifen Citrate Loaded Span-Based Nano-Vesicles on Human Breast Adenocarcinoma Cells.

Kassem MA, Megahed MA, Abu Elyazid SK, Abd-Allah FI, Abdelghany TM, Al-Abd AM, El-Say KM.

AAPS PharmSciTech. 2018 May;19(4):1529-1543. doi: 10.1208/s12249-018-0962-y. Epub 2018 Feb 22.


Effect of finasteride particle size reduction on its pharmacokinetic, tissue distribution and cellular permeation.

Ahmed TA, Al-Abd AM.

Drug Deliv. 2018 Nov;25(1):555-563. doi: 10.1080/10717544.2018.1440446.


Cytotoxicity of thymoquinone alone or in combination with cisplatin (CDDP) against oral squamous cell carcinoma in vitro.

Alaufi OM, Noorwali A, Zahran F, Al-Abd AM, Al-Attas S.

Sci Rep. 2017 Oct 13;7(1):13131. doi: 10.1038/s41598-017-13357-5.


Phenolics Isolated from Aframomum meleguta Enhance Proliferation and Ossification Markers in Bone Cells.

Abdel-Naim AB, Alghamdi AA, Algandaby MM, Al-Abbasi FA, Al-Abd AM, Abdallah HM, El-Halawany AM, Hattori M.

Molecules. 2017 Sep 4;22(9). pii: E1467. doi: 10.3390/molecules22091467.


Anti-angiogenic agents for the treatment of solid tumors: Potential pathways, therapy and current strategies - A review.

Al-Abd AM, Alamoudi AJ, Abdel-Naim AB, Neamatallah TA, Ashour OM.

J Adv Res. 2017 Nov;8(6):591-605. doi: 10.1016/j.jare.2017.06.006. Epub 2017 Jun 27. Review.


New xanthones and cytotoxic constituents from Garcinia mangostana fruit hulls against human hepatocellular, breast, and colorectal cancer cell lines.

Mohamed GA, Al-Abd AM, El-Halawany AM, Abdallah HM, Ibrahim SRM.

J Ethnopharmacol. 2017 Feb 23;198:302-312. doi: 10.1016/j.jep.2017.01.030. Epub 2017 Jan 18.


Molecular Mimics of Classic P-Glycoprotein Inhibitors as Multidrug Resistance Suppressors and Their Synergistic Effect on Paclitaxel.

El-Araby ME, Omar AM, Khayat MT, Assiri HA, Al-Abd AM.

PLoS One. 2017 Jan 9;12(1):e0168938. doi: 10.1371/journal.pone.0168938. eCollection 2017.


Didox and resveratrol sensitize colorectal cancer cells to doxorubicin via activating apoptosis and ameliorating P-glycoprotein activity.

Khaleel SA, Al-Abd AM, Ali AA, Abdel-Naim AB.

Sci Rep. 2016 Nov 14;6:36855. doi: 10.1038/srep36855.


Antiproliferative Scalarane-Based Metabolites from the Red Sea Sponge Hyrtios erectus.

Elhady SS, Al-Abd AM, El-Halawany AM, Alahdal AM, Hassanean HA, Ahmed SA.

Mar Drugs. 2016 Jul 8;14(7). pii: E130. doi: 10.3390/md14070130.


Gingerol Synergizes the Cytotoxic Effects of Doxorubicin against Liver Cancer Cells and Protects from Its Vascular Toxicity.

Al-Abbasi FA, Alghamdi EA, Baghdadi MA, Alamoudi AJ, El-Halawany AM, El-Bassossy HM, Aseeri AH, Al-Abd AM.

Molecules. 2016 Jul 8;21(7). pii: E886. doi: 10.3390/molecules21070886.


Transcriptional profiling of breast cancer cells in response to mevinolin: Evidence of cell cycle arrest, DNA degradation and apoptosis.

Mahmoud AM, Aboul-Soud MA, Han J, Al-Sheikh YA, Al-Abd AM, El-Shemy HA.

Int J Oncol. 2016 May;48(5):1886-94. doi: 10.3892/ijo.2016.3418. Epub 2016 Mar 4.


Effects of plant-derived anti-leukemic drugs on individualized leukemic cell population profiles in Egyptian patients.

Aboul-Soud MA, El-Shemy HA, Aboul-Enein KM, Mahmoud AM, Al-Abd AM, Lightfoot DA.

Oncol Lett. 2016 Jan;11(1):642-648. Epub 2015 Nov 13.


Antiproliferative effects of triterpenoidal derivatives, obtained from the marine sponge Siphonochalina sp., on human hepatic and colorectal cancer cells.

Abdel-Lateff A, Al-Abd AM, Alahdal AM, Alarif WM, Ayyad SE, Al-Lihaibi SS, Hegazy ME, Al Mohammadi A, Abdelghany TM, Abdel-Naim AB, Moustafa MA, Banjer ZM, Azhar AS.

Z Naturforsch C. 2016;71(1-2):29-35. doi: 10.1515/znc-2015-0160.


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