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Items: 1 to 20 of 50

1.

Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1H-indole (D2AAK1_3) as Dopamine D₂ Receptor Ligand.

Kondej M, Bartyzel A, Pitucha M, Wróbel TM, Silva AG, Matosiuk D, Castro M, Kaczor AA.

Molecules. 2018 Sep 4;23(9). pii: E2249. doi: 10.3390/molecules23092249.

2.

Current Concepts and Treatments of Schizophrenia.

Stępnicki P, Kondej M, Kaczor AA.

Molecules. 2018 Aug 20;23(8). pii: E2087. doi: 10.3390/molecules23082087. Review.

3.

Protein-Protein Docking in Drug Design and Discovery.

Kaczor AA, Bartuzi D, Stępniewski TM, Matosiuk D, Selent J.

Methods Mol Biol. 2018;1762:285-305. doi: 10.1007/978-1-4939-7756-7_15.

PMID:
29594778
4.

Comparative molecular field analysis and molecular dynamics studies of the dopamine D2 receptor antagonists without a protonatable nitrogen atom.

Kaczor AA, Żuk J, Matosiuk D.

Med Chem Res. 2018;27(4):1149-1166. doi: 10.1007/s00044-018-2137-5. Epub 2018 Feb 13.

5.

Molecular interactions of type I and type II positive allosteric modulators with the human α7 nicotinic acetylcholine receptor: an in silico study.

Targowska-Duda KM, Kaczor AA, Jozwiak K, Arias HR.

J Biomol Struct Dyn. 2018 Feb 16:1-29. doi: 10.1080/07391102.2018.1427634. [Epub ahead of print]

PMID:
29363414
6.

Molecular mechanisms of allosteric probe dependence in μ opioid receptor.

Bartuzi D, Kaczor AA, Matosiuk D.

J Biomol Struct Dyn. 2017 Dec 27:1-12. doi: 10.1080/07391102.2017.1417914. [Epub ahead of print]

PMID:
29241414
7.

Challenges and Opportunities in Drug Discovery of Biased Ligands.

Rodríguez-Espigares I, Kaczor AA, Stepniewski TM, Selent J.

Methods Mol Biol. 2018;1705:321-334. doi: 10.1007/978-1-4939-7465-8_14. Review.

PMID:
29188569
8.

Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs.

Bartuzi D, Kaczor AA, Matosiuk D.

Methods Mol Biol. 2018;1705:297-319. doi: 10.1007/978-1-4939-7465-8_13. Review.

PMID:
29188568
9.

Novel thiosemicarbazide derivatives with 4-nitrophenyl group as multi-target drugs: α-glucosidase inhibitors with antibacterial and antiproliferative activity.

Wos M, Miazga-Karska M, Kaczor AA, Klimek K, Karczmarzyk Z, Kowalczuk D, Wysocki W, Ginalska G, Urbanczyk-Lipkowska Z, Morawiak M, Pitucha M.

Biomed Pharmacother. 2017 Sep;93:1269-1276. doi: 10.1016/j.biopha.2017.07.049.

PMID:
28747001
10.

Signaling within Allosteric Machines: Signal Transmission Pathways Inside G Protein-Coupled Receptors.

Bartuzi D, Kaczor AA, Matosiuk D.

Molecules. 2017 Jul 15;22(7). pii: E1188. doi: 10.3390/molecules22071188. Review.

11.

Recent Advances and Applications of Molecular Docking to G Protein-Coupled Receptors.

Bartuzi D, Kaczor AA, Targowska-Duda KM, Matosiuk D.

Molecules. 2017 Feb 22;22(2). pii: E340. doi: 10.3390/molecules22020340. Review.

12.

Novel Antibacterial Compounds and their Drug Targets - Successes and Challenges.

Kaczor AA, Polski A, Sobótka-Polska K, Pachuta-Stec A, Makarska-Bialokoz M, Pitucha M.

Curr Med Chem. 2017;24(18):1948-1982. doi: 10.2174/0929867323666161213102127. Review.

PMID:
27978802
13.

Corrigendum to "In vitro, molecular modeling and behavioral studies of '3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic" [Neurochem. Int. 96 (2016) 84-99].

Kaczor AA, Targowska-Duda KM, Budzyńska B, Biała G, Silva AG, Castro M.

Neurochem Int. 2016 Nov;100:178-180. doi: 10.1016/j.neuint.2016.10.010. No abstract available.

PMID:
27825475
14.

In silico Exploration of the Conformational Universe of GPCRs.

Rodríguez-Espigares I, Kaczor AA, Selent J.

Mol Inform. 2016 Jul;35(6-7):227-37. doi: 10.1002/minf.201600012. Epub 2016 May 27. Review.

PMID:
27492237
15.

The dopamine D2 receptor dimer and its interaction with homobivalent antagonists: homology modeling, docking and molecular dynamics.

Kaczor AA, Jörg M, Capuano B.

J Mol Model. 2016 Sep;22(9):203. doi: 10.1007/s00894-016-3065-2. Epub 2016 Aug 4.

16.

Synthesis and Pharmacological Evaluation of Novel 1-(1,4-Alkylaryldisubstituted-4,5-dihydro-1H-imidazo)-3-substituted Urea Derivatives.

Szacoń E, Rządkowska M, Kaczor AA, Kędzierska E, Orzelska-Górka J, Fidecka S, Matosiuk D.

Molecules. 2016 Apr 30;21(5). pii: E582. doi: 10.3390/molecules21050582.

17.

Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.

Arias HR, Ravazzini F, Targowska-Duda KM, Kaczor AA, Feuerbach D, Boffi JC, Draczkowski P, Montag D, Brown BM, Elgoyhen AB, Jozwiak K, Puia G.

Int J Biochem Cell Biol. 2016 Jul;76:19-30. doi: 10.1016/j.biocel.2016.04.015. Epub 2016 Apr 26.

PMID:
27129924
18.

Structure-Based Virtual Screening for Dopamine D2 Receptor Ligands as Potential Antipsychotics.

Kaczor AA, Silva AG, Loza MI, Kolb P, Castro M, Poso A.

ChemMedChem. 2016 Apr 5;11(7):718-29. doi: 10.1002/cmdc.201500599. Epub 2016 Mar 18.

PMID:
26990027
19.

In vitro, molecular modeling and behavioral studies of 3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic.

Kaczor AA, Targowska-Duda KM, Budzyńska B, Biała G, Silva AG, Castro M.

Neurochem Int. 2016 Jun;96:84-99. doi: 10.1016/j.neuint.2016.03.003. Epub 2016 Mar 8. Erratum in: Neurochem Int. 2016 Nov;100:178-180.

PMID:
26964765
20.

Computational methods for studying G protein-coupled receptors (GPCRs).

Kaczor AA, Rutkowska E, Bartuzi D, Targowska-Duda KM, Matosiuk D, Selent J.

Methods Cell Biol. 2016;132:359-99. doi: 10.1016/bs.mcb.2015.11.002. Epub 2015 Dec 24.

PMID:
26928552

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