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Items: 15

1.

Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules.

Zhou G, Sprengers D, Mancham S, Erkens R, Boor PPC, van Beek AA, Doukas M, Noordam L, Campos Carrascosa L, de Ruiter V, van Leeuwen RWF, Polak WG, de Jonge J, Groot Koerkamp B, van Rosmalen B, van Gulik TM, Verheij J, IJzermans JNM, Bruno MJ, Kwekkeboom J.

J Hepatol. 2019 Oct;71(4):753-762. doi: 10.1016/j.jhep.2019.05.026. Epub 2019 Jun 11.

PMID:
31195061
2.

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 -/Δ7 mice.

van der Lugt B, van Beek AA, Aalvink S, Meijer B, Sovran B, Vermeij WP, Brandt RMC, de Vos WM, Savelkoul HFJ, Steegenga WT, Belzer C.

Immun Ageing. 2019 Mar 8;16:6. doi: 10.1186/s12979-019-0145-z. eCollection 2019.

3.

Age-associated Impairment of the Mucus Barrier Function is Associated with Profound Changes in Microbiota and Immunity.

Sovran B, Hugenholtz F, Elderman M, Van Beek AA, Graversen K, Huijskes M, Boekschoten MV, Savelkoul HFJ, De Vos P, Dekker J, Wells JM.

Sci Rep. 2019 Feb 5;9(1):1437. doi: 10.1038/s41598-018-35228-3.

4.

GITR ligation enhances functionality of tumor-infiltrating T cells in hepatocellular carcinoma.

van Beek AA, Zhou G, Doukas M, Boor PPC, Noordam L, Mancham S, Campos Carrascosa L, van der Heide-Mulder M, Polak WG, Ijzermans JNM, Pan Q, Heirman C, Mahne A, Bucktrout SL, Bruno MJ, Sprengers D, Kwekkeboom J.

Int J Cancer. 2019 Aug 15;145(4):1111-1124. doi: 10.1002/ijc.32181. Epub 2019 Feb 27.

5.

The damage-associated molecular pattern HMGB1 is released early after clinical hepatic ischemia/reperfusion.

van Golen RF, Reiniers MJ, Marsman G, Alles LK, van Rooyen DM, Petri B, Van der Mark VA, van Beek AA, Meijer B, Maas MA, Zeerleder S, Verheij J, Farrell GC, Luken BM, Teoh NC, van Gulik TM, Murphy MP, Heger M.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1192-1200. doi: 10.1016/j.bbadis.2019.01.014. Epub 2019 Jan 15.

PMID:
30658161
6.

Metabolic Alterations in Aging Macrophages: Ingredients for Inflammaging?

van Beek AA, Van den Bossche J, Mastroberardino PG, de Winther MPJ, Leenen PJM.

Trends Immunol. 2019 Feb;40(2):113-127. doi: 10.1016/j.it.2018.12.007. Epub 2019 Jan 6. Review.

PMID:
30626541
7.

Aged mice display altered numbers and phenotype of basophils, and bone marrow-derived basophil activation, with a limited role for aging-associated microbiota.

van Beek AA, Fransen F, Meijer B, de Vos P, Knol EF, Savelkoul HFJ.

Immun Ageing. 2018 Nov 29;15:32. doi: 10.1186/s12979-018-0135-6. eCollection 2018.

8.

Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer.

Zhou G, Noordam L, Sprengers D, Doukas M, Boor PPC, van Beek AA, Erkens R, Mancham S, Grünhagen D, Menon AG, Lange JF, Burger PJWA, Brandt A, Galjart B, Verhoef C, Kwekkeboom J, Bruno MJ.

Oncoimmunology. 2018 Apr 25;7(7):e1448332. doi: 10.1080/2162402X.2018.1448332. eCollection 2018.

9.

Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice.

Fransen F, van Beek AA, Borghuis T, Aidy SE, Hugenholtz F, van der Gaast-de Jongh C, Savelkoul HFJ, De Jonge MI, Boekschoten MV, Smidt H, Faas MM, de Vos P.

Front Immunol. 2017 Nov 2;8:1385. doi: 10.3389/fimmu.2017.01385. eCollection 2017.

10.

The Impact of Gut Microbiota on Gender-Specific Differences in Immunity.

Fransen F, van Beek AA, Borghuis T, Meijer B, Hugenholtz F, van der Gaast-de Jongh C, Savelkoul HF, de Jonge MI, Faas MM, Boekschoten MV, Smidt H, El Aidy S, de Vos P.

Front Immunol. 2017 Jun 30;8:754. doi: 10.3389/fimmu.2017.00754. eCollection 2017.

11.

Hypothermic perfusion with retrograde outflow during right hepatectomy is safe and feasible.

Reiniers MJ, Olthof PB, van Golen RF, Heger M, van Beek AA, Meijer B, Leen R, van Kuilenburg ABP, Mearadji B, Bennink RJ, Verheij J, van Gulik TM.

Surgery. 2017 Jul;162(1):48-58. doi: 10.1016/j.surg.2017.01.024. Epub 2017 Mar 24.

PMID:
28343696
12.

Warm ischemia time-dependent variation in liver damage, inflammation, and function in hepatic ischemia/reperfusion injury.

Olthof PB, van Golen RF, Meijer B, van Beek AA, Bennink RJ, Verheij J, van Gulik TM, Heger M.

Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):375-385. doi: 10.1016/j.bbadis.2016.10.022. Epub 2016 Oct 27.

13.

Supplementation with Lactobacillus plantarum WCFS1 Prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1-/Δ7 Mice.

van Beek AA, Sovran B, Hugenholtz F, Meijer B, Hoogerland JA, Mihailova V, van der Ploeg C, Belzer C, Boekschoten MV, Hoeijmakers JH, Vermeij WP, de Vos P, Wells JM, Leenen PJ, Nicoletti C, Hendriks RW, Savelkoul HF.

Front Immunol. 2016 Oct 7;7:408. eCollection 2016.

14.

Frontline Science: Tryptophan restriction arrests B cell development and enhances microbial diversity in WT and prematurely aging Ercc1-/Δ7 mice.

van Beek AA, Hugenholtz F, Meijer B, Sovran B, Perdijk O, Vermeij WP, Brandt RM, Barnhoorn S, Hoeijmakers JH, de Vos P, Leenen PJ, Hendriks RW, Savelkoul HF.

J Leukoc Biol. 2017 Apr;101(4):811-821. doi: 10.1189/jlb.1HI0216-062RR. Epub 2016 Jul 14.

15.

Inhibition of NF-κB in Tumor Cells Exacerbates Immune Cell Activation Following Photodynamic Therapy.

Broekgaarden M, Kos M, Jurg FA, van Beek AA, van Gulik TM, Heger M.

Int J Mol Sci. 2015 Aug 21;16(8):19960-77. doi: 10.3390/ijms160819960.

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