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Items: 12


Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia.

Barve A, Vega A, Shah PP, Ghare S, Casson L, Wunderlich M, Siskind LJ, Beverly LJ.

Cells. 2019 Oct 25;8(11). pii: E1322. doi: 10.3390/cells8111322.


Cell Type Purification by Single-Cell Transcriptome-Trained Sorting.

Baron CS, Barve A, Muraro MJ, van der Linden R, Dharmadhikari G, Lyubimova A, de Koning EJP, van Oudenaarden A.

Cell. 2019 Oct 3;179(2):527-542.e19. doi: 10.1016/j.cell.2019.08.006.


Primary lung cancer samples cultured under microenvironment-mimetic conditions enrich for mesenchymal stem-like cells that promote metastasis.

Saforo D, Omer L, Smolenkov A, Barve A, Casson L, Boyd N, Clark G, Siskind L, Beverly L.

Sci Rep. 2019 Mar 12;9(1):4177. doi: 10.1038/s41598-019-40519-4.


Comparative utility of NRG and NRGS mice for the study of normal hematopoiesis, leukemogenesis, and therapeutic response.

Barve A, Casson L, Krem M, Wunderlich M, Mulloy JC, Beverly LJ.

Exp Hematol. 2018 Nov;67:18-31. doi: 10.1016/j.exphem.2018.08.004. Epub 2018 Aug 17.


The Antiarrhythmic Drug, Amiodarone, Decreases AKT Activity and Sensitizes Human Acute Myeloid Leukemia Cells to Apoptosis by ABT-263.

Ketchem CJ, Kucera C, Barve A, Beverly LJ.

Am J Med Sci. 2018 May;355(5):488-496. doi: 10.1016/j.amjms.2018.01.011. Epub 2018 Feb 6.


Exhaustive Analysis of a Genotype Space Comprising 10(15 )Central Carbon Metabolisms Reveals an Organization Conducive to Metabolic Innovation.

Hosseini SR, Barve A, Wagner A.

PLoS Comput Biol. 2015 Aug 7;11(8):e1004329. doi: 10.1371/journal.pcbi.1004329. eCollection 2015 Aug.


Historical contingency and the gradual evolution of metabolic properties in central carbon and genome-scale metabolisms.

Barve A, Hosseini SR, Martin OC, Wagner A.

BMC Syst Biol. 2014 Apr 23;8:48. doi: 10.1186/1752-0509-8-48.


A latent capacity for evolutionary innovation through exaptation in metabolic systems.

Barve A, Wagner A.

Nature. 2013 Aug 8;500(7461):203-6. doi: 10.1038/nature12301. Epub 2013 Jul 14.


Growth temperature and genome size in bacteria are negatively correlated, suggesting genomic streamlining during thermal adaptation.

Sabath N, Ferrada E, Barve A, Wagner A.

Genome Biol Evol. 2013;5(5):966-77. doi: 10.1093/gbe/evt050.


Superessential reactions in metabolic networks.

Barve A, Rodrigues JF, Wagner A.

Proc Natl Acad Sci U S A. 2012 May 1;109(18):E1121-30. doi: 10.1073/pnas.1113065109. Epub 2012 Apr 16.


A kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coli.

Barve A, Gupta A, Solapure SM, Kumar A, Ramachandran V, Seshadri K, Vali S, Datta S.

Adv Appl Bioinform Chem. 2010;3:97-110. doi: 10.2147/AABC.S14368. Epub 2010 Dec 7.


Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells.

Jani TS, Gobejishvili L, Hote PT, Barve AS, Joshi-Barve S, Kharebava G, Suttles J, Chen T, McClain CJ, Barve S.

Cell Res. 2009 Mar;19(3):358-69. doi: 10.1038/cr.2008.314.


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