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Items: 1 to 20 of 37

1.

Differential MicroRNA Landscape Triggered by Estrogens in Cancer Associated Fibroblasts (CAFs) of Primary and Metastatic Breast Tumors.

Vivacqua A, Muoio MG, Miglietta AM, Maggiolini M.

Cancers (Basel). 2019 Mar 23;11(3). pii: E412. doi: 10.3390/cancers11030412.

2.

GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor Progression.

Santolla MF, Vivacqua A, Lappano R, Rigiracciolo DC, Cirillo F, Galli GR, Talia M, Brunetti G, Miglietta AM, Belfiore A, Maggiolini M.

Cells. 2019 Mar 7;8(3). pii: E223. doi: 10.3390/cells8030223.

3.

Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells.

Rigiracciolo DC, Santolla MF, Lappano R, Vivacqua A, Cirillo F, Galli GR, Talia M, Muglia L, Pellegrino M, Nohata N, Di Martino MT, Maggiolini M.

J Exp Clin Cancer Res. 2019 Feb 6;38(1):58. doi: 10.1186/s13046-019-1056-8.

4.

miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs).

Vivacqua A, Sebastiani A, Miglietta AM, Rigiracciolo DC, Cirillo F, Galli GR, Talia M, Santolla MF, Lappano R, Giordano F, Panno ML, Maggiolini M.

Cells. 2018 Nov 9;7(11). pii: E203. doi: 10.3390/cells7110203.

5.

miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling.

Santolla MF, Lappano R, Cirillo F, Rigiracciolo DC, Sebastiani A, Abonante S, Tassone P, Tagliaferri P, Di Martino MT, Maggiolini M, Vivacqua A.

J Exp Clin Cancer Res. 2018 May 2;37(1):94. doi: 10.1186/s13046-018-0767-6.

6.

GPER is involved in the regulation of the estrogen-metabolizing CYP1B1 enzyme in breast cancer.

Cirillo F, Pellegrino M, Malivindi R, Rago V, Avino S, Muto L, Dolce V, Vivacqua A, Rigiracciolo DC, De Marco P, Sebastiani A, Abonante S, Nakajima M, Lappano R, Maggiolini M.

Oncotarget. 2017 Nov 20;8(63):106608-106624. doi: 10.18632/oncotarget.22541. eCollection 2017 Dec 5.

7.

Recent Advances on the Role of microRNAs in both Insulin Resistance and Cancer.

Vivacqua A, De Marco P, Belfiore A, Maggiolini M.

Curr Pharm Des. 2017;23(25):3658-3666. doi: 10.2174/1381612823666170622105123. Review.

PMID:
28641547
8.

Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells.

Avino S, De Marco P, Cirillo F, Santolla MF, De Francesco EM, Perri MG, Rigiracciolo D, Dolce V, Belfiore A, Maggiolini M, Lappano R, Vivacqua A.

Oncotarget. 2016 Aug 16;7(33):52710-52728. doi: 10.18632/oncotarget.10348.

9.

GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts.

Pisano A, Santolla MF, De Francesco EM, De Marco P, Rigiracciolo DC, Perri MG, Vivacqua A, Abonante S, Cappello AR, Dolce V, Belfiore A, Maggiolini M, Lappano R.

Mol Carcinog. 2017 Feb;56(2):580-593. doi: 10.1002/mc.22518. Epub 2016 Jul 4.

PMID:
27341075
10.

GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response.

De Marco P, Lappano R, De Francesco EM, Cirillo F, Pupo M, Avino S, Vivacqua A, Abonante S, Picard D, Maggiolini M.

Sci Rep. 2016 Apr 13;6:24354. doi: 10.1038/srep24354.

11.

Androgens downregulate miR-21 expression in breast cancer cells underlining the protective role of androgen receptor.

Casaburi I, Cesario MG, Donà A, Rizza P, Aquila S, Avena P, Lanzino M, Pellegrino M, Vivacqua A, Tucci P, Morelli C, Andò S, Sisci D.

Oncotarget. 2016 Mar 15;7(11):12651-61. doi: 10.18632/oncotarget.7207.

12.

The G protein estrogen receptor (GPER) is regulated by endothelin-1 mediated signaling in cancer cells.

Bartella V, De Francesco EM, Perri MG, Curcio R, Dolce V, Maggiolini M, Vivacqua A.

Cell Signal. 2016 Feb;28(2):61-71. doi: 10.1016/j.cellsig.2015.11.010. Epub 2015 Nov 19.

PMID:
26607335
13.

Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands.

Rosano C, Ponassi M, Santolla MF, Pisano A, Felli L, Vivacqua A, Maggiolini M, Lappano R.

AAPS J. 2016 Jan;18(1):41-6. doi: 10.1208/s12248-015-9844-3. Epub 2015 Nov 16. Review.

14.

Estrogenic gper signaling regulates mir144 expression in cancer cells and cancer-associated fibroblasts (cafs).

Vivacqua A, De Marco P, Santolla MF, Cirillo F, Pellegrino M, Panno ML, Abonante S, Maggiolini M.

Oncotarget. 2015 Jun 30;6(18):16573-87.

15.

Novel Aspects Concerning the Functional Cross-Talk between the Insulin/IGF-I System and Estrogen Signaling in Cancer Cells.

De Marco P, Cirillo F, Vivacqua A, Malaguarnera R, Belfiore A, Maggiolini M.

Front Endocrinol (Lausanne). 2015 Mar 6;6:30. doi: 10.3389/fendo.2015.00030. eCollection 2015. Review.

16.

GPER1 is regulated by insulin in cancer cells and cancer-associated fibroblasts.

De Marco P, Romeo E, Vivacqua A, Malaguarnera R, Abonante S, Romeo F, Pezzi V, Belfiore A, Maggiolini M.

Endocr Relat Cancer. 2014 Oct;21(5):739-53. doi: 10.1530/ERC-14-0245. Epub 2014 Jul 10.

PMID:
25012984
17.

The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs).

Pupo M, Vivacqua A, Perrotta I, Pisano A, Aquila S, Abonante S, Gasperi-Campani A, Pezzi V, Maggiolini M.

Mol Cell Endocrinol. 2013 Aug 25;376(1-2):23-32. doi: 10.1016/j.mce.2013.05.023. Epub 2013 Jun 5.

PMID:
23748028
18.

In vitro mechanism for downregulation of ER-α expression by epigallocatechin gallate in ER+/PR+ human breast cancer cells.

De Amicis F, Russo A, Avena P, Santoro M, Vivacqua A, Bonofiglio D, Mauro L, Aquila S, Tramontano D, Fuqua SA, Andò S.

Mol Nutr Food Res. 2013 May;57(5):840-53. doi: 10.1002/mnfr.201200560. Epub 2013 Jan 16.

19.

G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts.

Santolla MF, Lappano R, De Marco P, Pupo M, Vivacqua A, Sisci D, Abonante S, Iacopetta D, Cappello AR, Dolce V, Maggiolini M.

J Biol Chem. 2012 Dec 21;287(52):43234-45. doi: 10.1074/jbc.M112.417303. Epub 2012 Nov 7.

20.

GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells.

Vivacqua A, Romeo E, De Marco P, De Francesco EM, Abonante S, Maggiolini M.

Breast Cancer Res Treat. 2012 Jun;133(3):1025-35. doi: 10.1007/s10549-011-1901-8. Epub 2011 Dec 7.

PMID:
22147081

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