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Items: 1 to 20 of 38


Challenges with stopping long-term nucleos(t)ide analogue therapy in patients with chronic hepatitis B.

Liem KS, Gehring AJ, Feld JJ, Janssen HLA.

Gastroenterology. 2019 Dec 3. pii: S0016-5085(19)41872-6. doi: 10.1053/j.gastro.2019.10.050. [Epub ahead of print] No abstract available.


A global scientific strategy to cure hepatitis B.

Revill PA, Chisari FV, Block JM, Dandri M, Gehring AJ, Guo H, Hu J, Kramvis A, Lampertico P, Janssen HLA, Levrero M, Li W, Liang TJ, Lim SG, Lu F, Penicaud MC, Tavis JE, Thimme R; Members of the ICE-HBV Working Groups; ICE-HBV Stakeholders Group Chairs; ICE-HBV Senior Advisors, Zoulim F.

Lancet Gastroenterol Hepatol. 2019 Jul;4(7):545-558. doi: 10.1016/S2468-1253(19)30119-0. Epub 2019 Apr 10. Erratum in: Lancet Gastroenterol Hepatol. 2019 Jul;4(7):e7.


Host-pathogen interactions in chronic HBV infection and transplantation of HCV-positive organs.

Feld JJ, Gehring AJ.

Nat Rev Gastroenterol Hepatol. 2019 Feb;16(2):77-78. doi: 10.1038/s41575-018-0101-y. Review. No abstract available.


Targeting Innate and Adaptive Immune Responses to Cure Chronic HBV Infection.

Gehring AJ, Protzer U.

Gastroenterology. 2019 Jan;156(2):325-337. doi: 10.1053/j.gastro.2018.10.032. Epub 2018 Oct 24. Review.


New treatments to reach functional cure: Rationale and challenges for emerging immune-based therapies.

Gehring AJ.

Best Pract Res Clin Gastroenterol. 2017 Jun;31(3):337-345. doi: 10.1016/j.bpg.2017.05.004. Epub 2017 May 25. Review.


Type I Interferon Responses Drive Intrahepatic T cells to Promote Metabolic Syndrome.

Ghazarian M, Revelo XS, Nøhr MK, Luck H, Zeng K, Lei H, Tsai S, Schroer SA, Park YJ, Chng MHY, Shen L, D'Angelo JA, Horton P, Chapman WC, Brockmeier D, Woo M, Engleman EG, Adeyi O, Hirano N, Jin T, Gehring AJ, Winer S, Winer DA.

Sci Immunol. 2017 Apr 21;2(10). pii: eaai7616. doi: 10.1126/sciimmunol.aai7616.


The role of innate immunity in the immunopathology and treatment of HBV infection.

Maini MK, Gehring AJ.

J Hepatol. 2016 Apr;64(1 Suppl):S60-S70. doi: 10.1016/j.jhep.2016.01.028. Review.


Trained immunity in newborn infants of HBV-infected mothers.

Hong M, Sandalova E, Low D, Gehring AJ, Fieni S, Amadei B, Urbani S, Chong YS, Guccione E, Bertoletti A.

Nat Commun. 2015 Mar 25;6:6588. doi: 10.1038/ncomms7588.


Reply to: "To target or not to target viral antigens in HBV related HCC?".

Qasim W, Brunetto M, Gehring AJ, Maini MK, Bonino F, Stauss H, Bertoletti A.

J Hepatol. 2015 Jun;62(6):1450-2. doi: 10.1016/j.jhep.2015.02.026. Epub 2015 Feb 21. No abstract available.


Dissecting the dendritic cell controversy in chronic hepatitis B virus infection.

Gehring AJ, Ann D'Angelo J.

Cell Mol Immunol. 2015 May;12(3):283-91. doi: 10.1038/cmi.2014.95. Epub 2014 Nov 3. Review.


Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient.

Qasim W, Brunetto M, Gehring AJ, Xue SA, Schurich A, Khakpoor A, Zhan H, Ciccorossi P, Gilmour K, Cavallone D, Moriconi F, Farzhenah F, Mazzoni A, Chan L, Morris E, Thrasher A, Maini MK, Bonino F, Stauss H, Bertoletti A.

J Hepatol. 2015 Feb;62(2):486-91. doi: 10.1016/j.jhep.2014.10.001. Epub 2014 Oct 13.


A whole recombinant yeast-based therapeutic vaccine elicits HBV X, S and Core specific T cells in mice and activates human T cells recognizing epitopes linked to viral clearance.

King TH, Kemmler CB, Guo Z, Mann D, Lu Y, Coeshott C, Gehring AJ, Bertoletti A, Ho ZZ, Delaney W, Gaggar A, Subramanian GM, McHutchison JG, Shrivastava S, Lee YJ, Kottilil S, Bellgrau D, Rodell T, Apelian D.

PLoS One. 2014 Jul 22;9(7):e101904. doi: 10.1371/journal.pone.0101904. eCollection 2014.


Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver.

Jo J, Tan AT, Ussher JE, Sandalova E, Tang XZ, Tan-Garcia A, To N, Hong M, Chia A, Gill US, Kennedy PT, Tan KC, Lee KH, De Libero G, Gehring AJ, Willberg CB, Klenerman P, Bertoletti A.

PLoS Pathog. 2014 Jun 26;10(6):e1004210. doi: 10.1371/journal.ppat.1004210. eCollection 2014 Jun.


Building and optimizing a virus-specific T cell receptor library for targeted immunotherapy in viral infections.

Banu N, Chia A, Ho ZZ, Garcia AT, Paravasivam K, Grotenbreg GM, Bertoletti A, Gehring AJ.

Sci Rep. 2014 Feb 25;4:4166. doi: 10.1038/srep04166.


Immune therapeutic strategies in chronic hepatitis B virus infection: virus or inflammation control?

Bertoletti A, Gehring AJ.

PLoS Pathog. 2013;9(12):e1003784. doi: 10.1371/journal.ppat.1003784. Epub 2013 Dec 19. No abstract available.


How further suppression of virus replication could improve current HBV treatment.

Tavis JE, Gehring AJ, Hu Y.

Expert Rev Anti Infect Ther. 2013 Aug;11(8):755-7. doi: 10.1586/14787210.2013.814846. No abstract available.


A practical approach to immunotherapy of hepatocellular carcinoma using T cells redirected against hepatitis B virus.

Koh S, Shimasaki N, Suwanarusk R, Ho ZZ, Chia A, Banu N, Howland SW, Ong AS, Gehring AJ, Stauss H, Renia L, Sällberg M, Campana D, Bertoletti A.

Mol Ther Nucleic Acids. 2013 Aug 13;2:e114. doi: 10.1038/mtna.2013.43.


Mobilizing monocytes to cross-present circulating viral antigen in chronic infection.

Gehring AJ, Haniffa M, Kennedy PT, Ho ZZ, Boni C, Shin A, Banu N, Chia A, Lim SG, Ferrari C, Ginhoux F, Bertoletti A.

J Clin Invest. 2013 Sep;123(9):3766-76. doi: 10.1172/JCI66043. Epub 2013 Aug 1.


IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells.

Tang XZ, Jo J, Tan AT, Sandalova E, Chia A, Tan KC, Lee KH, Gehring AJ, De Libero G, Bertoletti A.

J Immunol. 2013 Apr 1;190(7):3142-52. doi: 10.4049/jimmunol.1203218. Epub 2013 Feb 27.


Conditional ligands for Asian HLA variants facilitate the definition of CD8+ T-cell responses in acute and chronic viral diseases.

Chang CX, Tan AT, Or MY, Toh KY, Lim PY, Chia AS, Froesig TM, Nadua KD, Oh HL, Leong HN, Hadrup SR, Gehring AJ, Tan YJ, Bertoletti A, Grotenbreg GM.

Eur J Immunol. 2013 Apr;43(4):1109-20. doi: 10.1002/eji.201243088. Epub 2013 Feb 14.

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