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Items: 1 to 20 of 27

1.

Spectroscopic and molecular docking studies reveal binding characteristics of nazartinib (EGF816) to human serum albumin.

Almehizia AA, AlRabiah H, Bakheit AH, Hassan ESG, Herqash RN, Abdelhameed AS.

R Soc Open Sci. 2020 Jan 15;7(1):191595. doi: 10.1098/rsos.191595. eCollection 2020 Jan.

PMID:
32218978
2.

Development of a highly sensitive ELISA for determination of darunavir in plasma samples using a polyclonal antibody with high affinity and specificity.

Almehizia AA, Herqash RN, Darwish IA.

Bioanalysis. 2020 Mar 27. doi: 10.4155/bio-2020-0034. [Epub ahead of print]

PMID:
32216564
3.

Antitumor properties of certain spirooxindoles towards hepatocellular carcinoma endowed with antioxidant activity.

Al-Rashood ST, Hamed AR, Hassan GS, Alkahtani HM, Almehizia AA, Alharbi A, Al-Sanea MM, Eldehna WM.

J Enzyme Inhib Med Chem. 2020 Dec;35(1):831-839. doi: 10.1080/14756366.2020.1743281.

PMID:
32208781
4.

Modified Screen-Printed Potentiometric Sensors based on Man-Tailored Biomimetics for Diquat Herbicide Determination.

Kamel AH, Amr AEE, Abdalla NS, El-Naggar M, Al-Omar MA, Almehizia AA.

Int J Environ Res Public Health. 2020 Feb 11;17(4). pii: E1138. doi: 10.3390/ijerph17041138.

5.

Modified Potentiometric Screen-Printed Electrodes Based on Imprinting Character for Sodium Deoxycholate Determination.

H Kamel A, Ezzat S, Ahmed MA, Amr AEE, A Almehizia A, A Al-Omar M.

Biomolecules. 2020 Feb 6;10(2). pii: E251. doi: 10.3390/biom10020251.

6.

Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and ╬▓-phenylalanine scaffolds: a molecular docking study.

Abdel-Aziz AA, El-Azab AS, AlSaif NA, Alanazi MM, El-Gendy MA, Obaidullah AJ, Alkahtani HM, Almehizia AA, Al-Suwaidan IA.

J Enzyme Inhib Med Chem. 2020 Dec;35(1):610-621. doi: 10.1080/14756366.2020.1722120.

7.

Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2.

Alkahtani HM, Abdalla AN, Obaidullah AJ, Alanazi MM, Almehizia AA, Alanazi MG, Ahmed AY, Alwassil OI, Darwish HW, Abdel-Aziz AA, El-Azab AS.

Bioorg Chem. 2020 Jan;95:103461. doi: 10.1016/j.bioorg.2019.103461. Epub 2019 Dec 3.

PMID:
31838290
8.

New anthranilic acid-incorporating N-benzenesulfonamidophthalimides as potent inhibitors of carbonic anhydrases I, II, IX, and XII: Synthesis, in vitro testing, and in silico assessment.

El-Azab AS, Abdel-Aziz AA, Bua S, Nocentini A, AlSaif NA, Almehizia AA, Alanazi MM, Hefnawy MM, Supuran CT.

Eur J Med Chem. 2019 Nov 1;181:111573. doi: 10.1016/j.ejmech.2019.111573. Epub 2019 Aug 1.

PMID:
31394463
9.

Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity.

Eldehna WM, Abdelrahman MA, Nocentini A, Bua S, Al-Rashood ST, Hassan GS, Bonardi A, Almehizia AA, Alkahtani HM, Alharbi A, Gratteri P, Supuran CT.

Bioorg Chem. 2019 Sep;90:103102. doi: 10.1016/j.bioorg.2019.103102. Epub 2019 Jul 2.

PMID:
31299596
10.

Synthesis, anticancer, apoptosis-inducing activities and EGFR and VEGFR2 assay mechanistic studies of 5,5-diphenylimidazolidine-2,4-dione derivatives: Molecular docking studies.

Alkahtani HM, Alanazi MM, Aleanizy FS, Alqahtani FY, Alhoshani A, Alanazi FE, Almehizia AA, Abdalla AN, Alanazi MG, El-Azab AS, Abdel-Aziz AA.

Saudi Pharm J. 2019 Jul;27(5):682-693. doi: 10.1016/j.jsps.2019.04.003. Epub 2019 Apr 3.

11.

Antioxidant activities and molecular docking of 2-thioxobenzo[g]quinazoline derivatives.

Al-Salahi R, Taie HAA, Bakheit AH, Marzouk M, Almehizia AA, Herqash R, Abuelizz HA.

Pharmacol Rep. 2019 Aug;71(4):695-700. doi: 10.1016/j.pharep.2019.04.003. Epub 2019 Apr 9.

12.

Novel Diamide-Based Benzenesulfonamides as Selective Carbonic Anhydrase IX Inhibitors Endowed with Antitumor Activity: Synthesis, Biological Evaluation and In Silico Insights.

Abdelrahman MA, Eldehna WM, Nocentini A, Bua S, Al-Rashood ST, Hassan GS, Bonardi A, Almehizia AA, Alkahtani HM, Alharbi A, Gratteri P, Supuran CT.

Int J Mol Sci. 2019 May 20;20(10). pii: E2484. doi: 10.3390/ijms20102484.

13.

Novel Carbon/PEDOT/PSS-Based Screen-Printed Biosensors for Acetylcholine Neurotransmitter and Acetylcholinesterase Detection in Human Serum.

Ashmawy NH, Almehizia AA, Youssef TA, El-Galil E Amr A, Al-Omar MA, Kamel AH.

Molecules. 2019 Apr 18;24(8). pii: E1539. doi: 10.3390/molecules24081539.

14.

Mechanistic interaction study of 5,6-Dichloro-2-[2-(pyridin-2-yl)ethyl]isoindoline-1,3-dione with bovine serum albumin by spectroscopic and molecular docking approaches.

Alanazi MM, Almehizia AA, Bakheit AH, Alsaif NA, Alkahtani HM, Wani TA.

Saudi Pharm J. 2019 Mar;27(3):341-347. doi: 10.1016/j.jsps.2018.12.001. Epub 2018 Dec 6.

15.

Synthesis and in vitro anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents.

Eldehna WM, Hassan GS, Al-Rashood ST, Al-Warhi T, Altyar AE, Alkahtani HM, Almehizia AA, Abdel-Aziz HA.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):322-332. doi: 10.1080/14756366.2018.1547286.

16.

A Novel Oxidovanadium (IV)-Orotate Complex as an Alternative Antidiabetic Agent: Synthesis, Characterization, and Biological Assessments.

Naglah AM, Al-Omar MA, Almehizia AA, Bhat MA, Afifi WM, Al-Wasidi AS, Al-Humaidi JY, Refat MS.

Biomed Res Int. 2018 Dec 23;2018:8108713. doi: 10.1155/2018/8108713. eCollection 2018.

17.

Investigation the antioxidant activity of benzo[g]triazoloquinazolines correlated with a DFT study.

Almehizia AA, Abuelizz HA, Taie HAA, ElHassane A, Marzouk M, Al-Salahi R.

Saudi Pharm J. 2019 Jan;27(1):133-137. doi: 10.1016/j.jsps.2018.09.006. Epub 2018 Sep 11.

18.

Synthesis, characterization and antidiabetic effects of vanadyl(II) adenosine monophosphate amino acid mixed-ligand complexes.

Naglah AM, Al-Omar MA, Kalmouch A, Alsuhaibani AM, El-Didamony AM, Hassan N, Taleb SA, Refat MS, Almehizia AA, Bhat MA, Al-Shakliah NS, Al-Humaidi JY, Al-Wasidi AS.

Future Med Chem. 2019 Jan 15. doi: 10.4155/fmc-2018-0471. [Epub ahead of print]

PMID:
30642200
19.

Targeting microbial resistance: Synthesis, antibacterial evaluation, DNA binding and modeling study of new chalcone-based dithiocarbamate derivatives.

Ayman M, El-Messery SM, Habib EE, Al-Rashood ST, Almehizia AA, Alkahtani HM, Hassan GS.

Bioorg Chem. 2019 Apr;85:282-292. doi: 10.1016/j.bioorg.2019.01.001. Epub 2019 Jan 3.

PMID:
30641322
20.

Synthesis, biological evaluations and computational studies of N-(3-(-2-(7-Chloroquinolin-2-yl)vinyl) benzylidene)anilines as fungal biofilm inhibitors.

Khan FAK, Kaduskar RN, Patil R, Patil RH, Ansari SA, Alkahtani HM, Almehizia AA, Shinde DB, Sangshetti JN.

Bioorg Med Chem Lett. 2019 Feb 15;29(4):623-630. doi: 10.1016/j.bmcl.2018.12.046. Epub 2018 Dec 21.

PMID:
30595445

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