Format

Send to

Choose Destination
Nutrients. 2018 Sep 10;10(9). pii: E1275. doi: 10.3390/nu10091275.

Compliance to Prenatal Iron and Folic Acid Supplement Use in Relation to Low Birth Weight in Lilongwe, Malawi.

Author information

1
Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI 48824, USA. achikakuda@luanar.ac.mw.
2
Department of Public Health, Food Studies and Nutrition, Syracuse University, Syracuse, NY 13244, USA. dshin03@syr.edu.
3
Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI 48824, USA. comsto37@msu.edu.
4
Department of Food and Nutrition, Hannam University, Daejeon 34054, Korea. sjsong@hnu.kr.
5
Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI 48824, USA. song@msu.edu.

Abstract

Prenatal iron and folic acid (IFA) supplements are offered free to all pregnant women in Malawi to reduce maternal anemia and improve birth outcomes. We investigated the association between self-reported compliance to IFA intake and risk of low birth weight (LBW). Pregnant women who attended Bwaila Maternity Wing of Lilongwe District Hospital for delivery were recruited (n = 220). We used a questionnaire to collect self-reported information on IFA use and maternal sociodemographic data. Before delivery, blood samples for maternal hemoglobin (Hb) and folate status, and upon delivery, birth weight, and other newborn anthropometrics were measured. We used multivariable logistic regression to determine risk of LBW by prenatal IFA intake. The self-reported number of IFA pills taken during pregnancy was positively associated with Hb, but not serum and RBC folate concentration: <45, 45⁻89 and ≥90 pills taken corresponded with mean (SD) Hb 10.7 (1.6), 11.3 (1.8), and 11.7 (1.6) g/dL, respectively (p = 0.006). The prevalence of LBW was 20.1%, 13.5% and 5.6% for those who reported taking IFA pills <45, 45⁻89, and ≥90 pills, respectively (p = 0.027). Taking >60 IFA pills reduced risk of LBW delivery (OR (95% CI) = 0.15 (0.03⁻0.70), p = 0.033) than taking ≤30 pills. Self-reported compliance to IFA use is valid for assessing prenatal supplement program in Malawi, especially Hb status, and can reduce the rate of LBW.

KEYWORDS:

Malawi; low birth weight; maternal anemia; prenatal iron and folic acid (IFA) supplements

PMID:
30201880
PMCID:
PMC6163556
DOI:
10.3390/nu10091275
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Multidisciplinary Digital Publishing Institute (MDPI) Icon for PubMed Central
Loading ...
Support Center