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Best matches for A. Dömling:

Immune Checkpoint PD-1/PD-L1: Is There Life Beyond Antibodies? Konstantinidou M et al. Angew Chem Int Ed Engl. (2018)

Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2. Zak KM et al. Structure. (2017)

How To Design a Successful p53-MDM2/X Interaction Inhibitor: A Thorough Overview Based on Crystal Structures. Estrada-Ortiz N et al. ChemMedChem. (2016)

Search results

Items: 1 to 20 of 151

1.

A fluorinated indole-based MDM2 antagonist selectively inhibits the growth of p53wt osteosarcoma cells.

Skalniak L, Twarda-Clapa A, Neochoritis CG, Surmiak E, Machula M, Wisniewska A, Labuzek B, Ali AM, Krzanik S, Dubin G, Groves M, Dömling A, Holak TA.

FEBS J. 2019 Feb 4. doi: 10.1111/febs.14774. [Epub ahead of print]

PMID:
30715803
2.

Tetrazoles via Multicomponent Reactions.

Neochoritis CG, Zhao T, Dömling A.

Chem Rev. 2019 Feb 13;119(3):1970-2042. doi: 10.1021/acs.chemrev.8b00564. Epub 2019 Feb 1.

PMID:
30707567
3.

Automated and Accelerated Synthesis of Indole Derivatives on a Nano-Scale.

Shaabani S, Xu R, Ahmadianmoghaddam M, Gao L, Stahorsky M, Olechno J, Ellson R, Kossenjans M, Helan V, Dömling A.

Green Chem. 2019 Jan 21;21(2):225-232. doi: 10.1039/C8GC03039A. Epub 2018 Dec 21.

PMID:
30686932
4.

Application of Silver Nanoparticles in the Multicomponent Reaction Domain: A Combined Catalytic Reduction Methodology to Efficiently Access Potential Hypertension or Inflammation Inhibitors.

Iordanidou D, Zarganes-Tzitzikas T, Neochoritis CG, Dömling A, Lykakis IN.

ACS Omega. 2018 Nov 30;3(11):16005-16013. doi: 10.1021/acsomega.8b02749. Epub 2018 Nov 27.

5.

Macrocycles: MCR synthesis and applications in drug discovery.

Abdelraheem EMM, Shaabani S, Dömling A.

Drug Discov Today Technol. 2018 Nov;29:11-17. doi: 10.1016/j.ddtec.2018.06.008. Epub 2018 Jul 12. Review.

PMID:
30471668
6.

The Catalytic Enantioselective Ugi Four-Component Reactions.

Shaabani S, Dömling A.

Angew Chem Int Ed Engl. 2018 Dec 10;57(50):16266-16268. doi: 10.1002/anie.201811129. Epub 2018 Nov 15. Review.

7.

Identification of potential antivirulence agents by substitution-oriented screening for inhibitors of Streptococcus pyogenes sortase A.

Wójcik M, Eleftheriadis N, Zwinderman MRH, Dömling ASS, Dekker FJ, Boersma YL.

Eur J Med Chem. 2019 Jan 1;161:93-100. doi: 10.1016/j.ejmech.2018.10.027. Epub 2018 Oct 15.

PMID:
30343193
8.

Production of "biobetter" glucarpidase variants to improve drug detoxification and antibody directed enzyme prodrug therapy for cancer treatment.

AlQahtani AD, Al-Mansoori L, Bashraheel SS, Rashidi FB, Al-Yafei A, Elsinga P, Domling A, Goda SK.

Eur J Pharm Sci. 2019 Jan 15;127:79-91. doi: 10.1016/j.ejps.2018.10.014. Epub 2018 Oct 19.

PMID:
30343151
9.

A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).

Shaabani S, Huizinga HPS, Butera R, Kouchi A, Guzik K, Magiera-Mularz K, Holak TA, Dömling A.

Expert Opin Ther Pat. 2018 Sep;28(9):665-678. doi: 10.1080/13543776.2018.1512706. Epub 2018 Sep 10. Review.

PMID:
30107136
10.

Multicomponent Reaction Based Synthesis of 1-Tetrazolylimidazo[1,5- a]pyridines.

Kurhade S, Diekstra E, Sutanto F, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A.

Org Lett. 2018 Jul 6;20(13):3871-3874. doi: 10.1021/acs.orglett.8b01452. Epub 2018 Jun 26.

11.

Triglyceride profiling in adipose tissues from obese insulin sensitive, insulin resistant and type 2 diabetes mellitus individuals.

Al-Sulaiti H, Diboun I, Banu S, Al-Emadi M, Amani P, Harvey TM, Dömling AS, Latiff A, Elrayess MA.

J Transl Med. 2018 Jun 26;16(1):175. doi: 10.1186/s12967-018-1548-x.

12.

Artificial Macrocycles as IL-17A/IL-17RA Antagonists.

Wang W, Groves MR, Dömling A.

Medchemcomm. 2018 Jan 1;9(1):22-26. doi: 10.1039/C7MD00464H. Epub 2017 Oct 25.

13.

Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment.

Rashidi FB, AlQhatani AD, Bashraheel SS, Shaabani S, Groves MR, Dömling A, Goda SK.

PLoS One. 2018 Apr 26;13(4):e0196254. doi: 10.1371/journal.pone.0196254. eCollection 2018.

14.

Guide for Selection of Relevant Cell Lines During the Evaluation of new Anti-Cancer Compounds.

Ruiz-Moreno AJ, Torres-Barrera P, Velázquez-Paniagua M, Dömling A, Velasco-Velázquez MA.

Anticancer Agents Med Chem. 2018;18(8):1072-1081. doi: 10.2174/1871520618666180220120544.

PMID:
29697026
15.

Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase.

Lunev S, Bosch SS, Batista FA, Wang C, Li J, Linzke M, Kruithof P, Chamoun G, Dömling ASS, Wrenger C, Groves MR.

Biochem Biophys Res Commun. 2018 Mar 11;497(3):835-842. doi: 10.1016/j.bbrc.2018.02.112. Epub 2018 Feb 21.

PMID:
29476738
16.

Synthesis of Highly Substituted Imidazole Uracil Containing Molecules via Ugi-4CR and Passerini-3CR.

Madhavachary R, Zarganes-Tzitzikas T, Patil P, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A.

ACS Comb Sci. 2018 Apr 9;20(4):192-196. doi: 10.1021/acscombsci.7b00145. Epub 2018 Feb 26.

17.

Diastereoselective One Pot Five-Component Reaction toward 4-(Tetrazole)-1,3-Oxazinanes.

Chandgude AL, Narducci D, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A.

RSC Adv. 2017;7(79):49995-49998. doi: 10.1039/C7RA07392E. Epub 2017 Oct 26.

18.

Discovery of chromenes as inhibitors of macrophage migration inhibitory factor.

Kok T, Wapenaar H, Wang K, Neochoritis CG, Zarganes-Tzitzikas T, Proietti G, Eleftheriadis N, Kurpiewska K, Kalinowska-Tłuścik J, Cool RH, Poelarends GJ, Dömling A, Dekker FJ.

Bioorg Med Chem. 2018 Mar 1;26(5):999-1005. doi: 10.1016/j.bmc.2017.12.032. Epub 2017 Dec 24.

PMID:
29428527
19.

Two-Step Macrocycle Synthesis by Classical Ugi Reaction.

Abdelraheem EMM, Khaksar S, Kurpiewska K, Kalinowska-Tłuścik J, Shaabani S, Dömling A.

J Org Chem. 2018 Feb 2;83(3):1441-1447. doi: 10.1021/acs.joc.7b02984. Epub 2018 Jan 24.

20.

Library-to-Library Synthesis of Highly Substituted α-Aminomethyl Tetrazoles via Ugi Reaction.

Patil P, Mishra B, Sheombarsing G, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A.

ACS Comb Sci. 2018 Feb 12;20(2):70-74. doi: 10.1021/acscombsci.7b00137. Epub 2018 Jan 4. Review.

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