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Items: 18

1.

The Effect of Biotinylated PAMAM G3 Dendrimers Conjugated with COX-2 Inhibitor (celecoxib) and PPARγ Agonist (Fmoc-L-Leucine) on Human Normal Fibroblasts, Immortalized Keratinocytes and Glioma Cells in Vitro.

Uram Ł, Misiorek M, Pichla M, Filipowicz-Rachwał A, Markowicz J, Wołowiec S, Wałajtys-Rode E.

Molecules. 2019 Oct 22;24(20). pii: E3801. doi: 10.3390/molecules24203801.

2.

Mixed-Generation PAMAM G3-G0 Megamer as a Drug Delivery System for Nimesulide: Antitumor Activity of the Conjugate Against Human Squamous Carcinoma and Glioblastoma Cells.

Zaręba M, Sareło P, Kopaczyńska M, Białońska A, Uram Ł, Walczak M, Aebisher D, Wołowiec S.

Int J Mol Sci. 2019 Oct 9;20(20). pii: E4998. doi: 10.3390/ijms20204998.

3.

Antitumor and anti-nematode activities of α-mangostin.

Markowicz J, Uram Ł, Sobich J, Mangiardi L, Maj P, Rode W.

Eur J Pharmacol. 2019 Nov 15;863:172678. doi: 10.1016/j.ejphar.2019.172678. Epub 2019 Sep 19.

PMID:
31542481
4.

Synthesis and Different Effects of Biotinylated PAMAM G3 Dendrimer Substituted with Nimesulide in Human Normal Fibroblasts and Squamous Carcinoma Cells.

Uram Ł, Filipowicz-Rachwał A, Misiorek M, Winiarz A, Wałajtys-Rode E, Wołowiec S.

Biomolecules. 2019 Sep 1;9(9). pii: E437. doi: 10.3390/biom9090437.

5.

Evaluation of the localization and biological effects of PAMAM G3 dendrimer-biotin/pyridoxal conjugate as HaCaT keratinocyte targeted nanocarrier.

Szuster M, Uram ŁS, Filipowicz-Rachwał A, Wołowiec S, Wałajtys-Rode E.

Acta Biochim Pol. 2019 Apr 9. doi: 10.18388/abp.2018_2767. [Epub ahead of print]

6.

Methotrexate-induced senescence of human colon cancer cells depends on p53 acetylation, but not genomic aberrations.

Dabrowska M, Skoneczny M, Uram L, Rode W.

Anticancer Drugs. 2019 Apr;30(4):374-382. doi: 10.1097/CAD.0000000000000731.

PMID:
30531292
7.

Study of chemical, physico-mechanical and biological properties of 4,4'-methylenebis(cyclohexyl isocyanate)-based polyurethane films.

Król P, Uram Ł, Król B, Pielichowska K, Walczak M.

Mater Sci Eng C Mater Biol Appl. 2018 Dec 1;93:483-494. doi: 10.1016/j.msec.2018.07.082. Epub 2018 Aug 10.

PMID:
30274081
8.

Biotinylated PAMAM G3 dendrimer conjugated with celecoxib and/or Fmoc-l-Leucine and its cytotoxicity for normal and cancer human cell lines.

Uram Ł, Filipowicz A, Misiorek M, Pieńkowska N, Markowicz J, Wałajtys-Rode E, Wołowiec S.

Eur J Pharm Sci. 2018 Nov 1;124:1-9. doi: 10.1016/j.ejps.2018.08.019. Epub 2018 Aug 15.

PMID:
30118847
9.

N(4)-[B-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan)methyl]-2'-deoxycytidine as a potential boron delivery agent with respect to glioblastoma.

Uram Ł, Nizioł J, Maj P, Sobich J, Rode W, Ruman T.

Biomed Pharmacother. 2017 Nov;95:749-755. doi: 10.1016/j.biopha.2017.08.134. Epub 2017 Sep 7.

PMID:
28888921
10.

Synthesis and biological evaluation of 4'-O-acetyl-isoxanthohumol and its analogues as antioxidant and antiproliferative agents.

Stompor M, Świtalska M, Podgórski R, Uram Ł, Aebisher D, Wietrzyk J.

Acta Biochim Pol. 2017;64(3):577-583. doi: 10.18388/abp.2017_1608. Epub 2017 Aug 12.

11.

Oxidative stress and inhibition of nitric oxide generation underlie methotrexate-induced senescence in human colon cancer cells.

Dabrowska M, Uram L, Zielinski Z, Rode W, Sikora E.

Mech Ageing Dev. 2018 Mar;170:22-29. doi: 10.1016/j.mad.2017.07.006. Epub 2017 Jul 21.

PMID:
28739375
12.

In Vitro Effect of 8-Prenylnaringenin and Naringenin on Fibroblasts and Glioblastoma Cells-Cellular Accumulation and Cytotoxicity.

Stompor M, Uram Ł, Podgórski R.

Molecules. 2017 Jun 30;22(7). pii: E1092. doi: 10.3390/molecules22071092.

13.

The effect of G3 PAMAM dendrimer conjugated with B-group vitamins on cell morphology, motility and ATP level in normal and cancer cells.

Uram Ł, Szuster M, Misiorek M, Filipowicz A, Wołowiec S, Wałajtys-Rode E.

Eur J Pharm Sci. 2017 May 1;102:275-283. doi: 10.1016/j.ejps.2017.03.022. Epub 2017 Mar 16.

PMID:
28323116
14.

Cellular uptake of glucoheptoamidated poly(amidoamine) PAMAM G3 dendrimer with amide-conjugated biotin, a potential carrier of anticancer drugs.

Uram Ł, Szuster M, Filipowicz A, Zaręba M, Wałajtys-Rode E, Wołowiec S.

Bioorg Med Chem. 2017 Jan 15;25(2):706-713. doi: 10.1016/j.bmc.2016.11.047. Epub 2016 Nov 25.

PMID:
27919613
15.

Different patterns of nuclear and mitochondrial penetration by the G3 PAMAM dendrimer and its biotin-pyridoxal bioconjugate BC-PAMAM in normal and cancer cells in vitro.

Uram Ł, Szuster M, Filipowicz A, Gargasz K, Wołowiec S, Wałajtys-Rode E.

Int J Nanomedicine. 2015 Sep 4;10:5647-61. doi: 10.2147/IJN.S87307. eCollection 2015.

16.

Biological activity of N(4)-boronated derivatives of 2'-deoxycytidine, potential agents for boron-neutron capture therapy.

Nizioł J, Uram Ł, Szuster M, Sekuła J, Ruman T.

Bioorg Med Chem. 2015 Oct 1;23(19):6297-304. doi: 10.1016/j.bmc.2015.08.026. Epub 2015 Aug 28.

PMID:
26344594
17.

In vitro cytotoxicity of the ternary PAMAM G3-pyridoxal-biotin bioconjugate.

Uram Ł, Szuster M, Gargasz K, Filipowicz A, Wałajtys-Rode E, Wołowiec S.

Int J Nanomedicine. 2013;8:4707-20. doi: 10.2147/IJN.S53254. Epub 2013 Dec 11.

18.

Brain dysplasia evoked by gamma irradiation at different stages of prenatal development leads to different tonic and clonic seizure reactivity.

Setkowicz Z, Gzieło-Jurek K, Uram Ł, Janicka D, Janeczko K.

Epilepsy Res. 2014 Jan;108(1):66-80. doi: 10.1016/j.eplepsyres.2013.10.010. Epub 2013 Oct 28.

PMID:
24239322

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