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Items: 1 to 20 of 30

1.

Synthesis, In Vitro Screening and Docking Studies of New Thiosemicarbazide Derivatives as Antitubercular Agents.

Pitucha M, Karczmarzyk Z, Swatko-Ossor M, Wysocki W, Wos M, Chudzik K, Ginalska G, Fruzinski A.

Molecules. 2019 Jan 11;24(2). pii: E251. doi: 10.3390/molecules24020251.

2.

Synthesis of unsymmetrical disulfanes bearing 1,2,4-triazine scaffold and their in vitro screening towards anti-breast cancer activity.

Branowska D, Ławecka J, Sobiczewski M, Karczmarzyk Z, Wysocki W, Wolińska E, Olender E, Mirosław B, Perzyna A, Bielawska A, Bielawski K.

Monatsh Chem. 2018;149(8):1409-1420. doi: 10.1007/s00706-018-2206-y. Epub 2018 Jun 27.

3.

Synthesis, Structure and Antiproliferative Activity of New pyrazolo[4,3- e]triazolo[4,5-b][1,2,4]triazine Derivatives.

Mojzych M, Tarasiuk P, Karczmarzyk Z, Juszczak M, Rzeski W, Fruzinski A, Wozny A.

Med Chem. 2018;14(1):53-59. doi: 10.2174/1573406413666171020114924.

PMID:
29065838
4.

Novel thiosemicarbazide derivatives with 4-nitrophenyl group as multi-target drugs: α-glucosidase inhibitors with antibacterial and antiproliferative activity.

Wos M, Miazga-Karska M, Kaczor AA, Klimek K, Karczmarzyk Z, Kowalczuk D, Wysocki W, Ginalska G, Urbanczyk-Lipkowska Z, Morawiak M, Pitucha M.

Biomed Pharmacother. 2017 Sep;93:1269-1276. doi: 10.1016/j.biopha.2017.07.049.

PMID:
28747001
5.

Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity.

Wróbel TM, Kosikowska U, Kaczor AA, Andrzejczuk S, Karczmarzyk Z, Wysocki W, Urbańczyk-Lipkowska Z, Morawiak M, Matosiuk D.

Molecules. 2015 Aug 13;20(8):14761-76. doi: 10.3390/molecules200814761.

6.

Synthetic approaches for sulfur derivatives containing 1,2,4-triazine moiety: their activity for in vitro screening towards two human cancer cell lines.

Karczmarzyk Z, Wysocki W, Urbańczyk-Lipkowska Z, Kalicki P, Bielawska A, Bielawski K, Ławecka J.

Chem Pharm Bull (Tokyo). 2015;63(7):531-7. doi: 10.1248/cpb.c15-00153.

7.

Discovery of nitroaryl urea derivatives with antiproliferative properties.

Wróbel TM, Kiełbus M, Kaczor AA, Kryštof V, Karczmarzyk Z, Wysocki W, Fruziński A, Król SK, Grabarska A, Stepulak A, Matosiuk D.

J Enzyme Inhib Med Chem. 2016 Aug;31(4):608-18. doi: 10.3109/14756366.2015.1057716. Epub 2015 Jun 26.

PMID:
26114307
8.

New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity.

Mojzych M, Karczmarzyk Z, Wysocki W, Ceruso M, Supuran CT, Kryštof V, Urbańczyk-Lipkowska Z, Kalicki P.

Bioorg Med Chem. 2015 Apr 1;23(7):1421-9. doi: 10.1016/j.bmc.2015.02.026. Epub 2015 Feb 21.

PMID:
25757603
9.

Structural studies, homology modeling and molecular docking of novel non-competitive antagonists of GluK1/GluK2 receptors.

Kaczor AA, Karczmarzyk Z, Fruziński A, Pihlaja K, Sinkkonen J, Wiinämaki K, Kronbach C, Unverferth K, Poso A, Matosiuk D.

Bioorg Med Chem. 2014 Jan 15;22(2):787-95. doi: 10.1016/j.bmc.2013.12.013. Epub 2013 Dec 12.

PMID:
24368028
10.

Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes.

Malinka W, Swiątek P, Sliwińska M, Szponar B, Gamian A, Karczmarzyk Z, Fruziński A.

Bioorg Med Chem. 2013 Sep 1;21(17):5282-91. doi: 10.1016/j.bmc.2013.06.027. Epub 2013 Jun 19.

11.

2-(5,6-Diphenyl-1,2,4-triazin-3-yl)aniline.

Mojzych M, Karczmarzyk Z, Fruziński A.

Acta Crystallogr Sect E Struct Rep Online. 2012 Dec 1;68(Pt 12):o3278. doi: 10.1107/S1600536812044194. Epub 2012 Nov 3.

12.

Ethyl 2-(3-methyl-5-sulfanyl-idene-4,5-dihydro-1H-1,2,4-triazol-4-yl)acetate.

Karczmarzyk Z, Pitucha M, Wysocki W, Fruziński A, Olender E.

Acta Crystallogr Sect E Struct Rep Online. 2012 Dec 1;68(Pt 12):o3264-5. doi: 10.1107/S1600536812044716. Epub 2012 Nov 3.

13.

3-Benzyl-4-ethyl-1H-1,2,4-triazole-5(4H)-thione.

Karczmarzyk Z, Pitucha M, Wysocki W, Pachuta-Stec A, Stańczuk A.

Acta Crystallogr Sect E Struct Rep Online. 2013 Feb 1;69(Pt 2):o155-6. doi: 10.1107/S1600536812051276. Epub 2013 Jan 4.

14.

The pseudo-Michael reaction of 1-aryl-4,5-dihydro-1H-imidazol-2-amines with ethyl ethoxymethylenecyanoacetate.

Kaczor AA, Kijkowska-Murak U, Pihlaja K, Sinkkonen J, Wysocki W, Karczmarzyk Z, Matosiuk D.

Monatsh Chem. 2013;144(8):1171-1182. Epub 2013 May 14.

15.

Structural and molecular docking studies of 4-benzyl-3-[(1-methylpyrrol- 2-yl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one with anticancer activity.

Kaczor AA, Pitucha M, Karczmarzyk Z, Wysocki W, Rzymowska J, Matosiuk D.

Med Chem. 2013 May;9(3):313-28.

PMID:
22741788
16.

2-(3-Chloro-5,6-diphenyl-2,5-dihydro-1,2,4-triazin-5-yl)-2-methyl-propane-nitrile.

Wolińska E, Karczmarzyk Z, Rykowski A, Urbańczyk-Lipkowska Z, Kalicki P.

Acta Crystallogr Sect E Struct Rep Online. 2012 Jun 1;68(Pt 6):o1938. doi: 10.1107/S1600536812023252. Epub 2012 May 31.

17.

Tosyl esters of cinchonidine and cinchonine alkaloids: the structure-reactivity relationship in the hydrolysis to 9-epibases.

Karczmarzyk Z, Lipińska TM, Wysocki W, Denisiuk M, Piechocka K.

Acta Crystallogr C. 2011 Sep;67(Pt 9):o346-9. doi: 10.1107/S0108270111027272. Epub 2011 Aug 5.

PMID:
21881184
18.

Derivatives of pyrrolo[3,4-d]pyridazinone, a new class of analgesic agents.

Malinka W, Redzicka A, Jastrzębska-Więsek M, Filipek B, Dybała M, Karczmarzyk Z, Urbańczyk-Lipkowska Z, Kalicki P.

Eur J Med Chem. 2011 Oct;46(10):4992-9. doi: 10.1016/j.ejmech.2011.08.006. Epub 2011 Aug 9.

PMID:
21864951
19.

5,5',6,6'-Tetra-methyl-3,3'-bi-1,2,4-tri-azine.

Wolińska E, Karczmarzyk Z, Rykowski A, Wysocki W.

Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1613. doi: 10.1107/S1600536811020691. Epub 2011 Jun 11.

20.

5,6,7,8-Tetra-hydro-quinolin-8-one.

Lipińska TM, Karczmarzyk Z, Wysocki W, Gruba E, Fruziński A.

Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1365. doi: 10.1107/S1600536811016175. Epub 2011 May 7.

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