Sort by
Items per page

Send to

Choose Destination

Search results

Items: 20


p38γ is essential for cell cycle progression and liver tumorigenesis.

Tomás-Loba A, Manieri E, González-Terán B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodríguez E, Pintor-Chocano A, Feixas F, López JA, Caballero B, Trakala M, Blanco Ó, Torres JL, Hernández-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, León M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J, Nevzorova YA, Cubero FJ, Bravo J, Vázquez J, Malumbres M, Marcos M, Osuna S, Sabio G.

Nature. 2019 Apr;568(7753):557-560. doi: 10.1038/s41586-019-1112-8. Epub 2019 Apr 10.


Alcoholic liver disease: Utility of animal models.

Lamas-Paz A, Hao F, Nelson LJ, Vázquez MT, Canals S, Gómez Del Moral M, Martínez-Naves E, Nevzorova YA, Cubero FJ.

World J Gastroenterol. 2018 Dec 7;24(45):5063-5075. doi: 10.3748/wjg.v24.i45.5063. Review.


Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma.

Sonntag R, Giebeler N, Nevzorova YA, Bangen JM, Fahrenkamp D, Lambertz D, Haas U, Hu W, Gassler N, Cubero FJ, Müller-Newen G, Abdallah AT, Weiskirchen R, Ticconi F, Costa IG, Barbacid M, Trautwein C, Liedtke C.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9282-9287. doi: 10.1073/pnas.1807155115. Epub 2018 Aug 27.


The Lieber-DeCarli Diet-A Flagship Model for Experimental Alcoholic Liver Disease.

Guo F, Zheng K, Benedé-Ubieto R, Cubero FJ, Nevzorova YA.

Alcohol Clin Exp Res. 2018 Oct;42(10):1828-1840. doi: 10.1111/acer.13840. Epub 2018 Aug 9. Review.


Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice.

Hao F, Cubero FJ, Ramadori P, Liao L, Haas U, Lambertz D, Sonntag R, Bangen JM, Gassler N, Hoss M, Streetz KL, Reissing J, Zimmermann HW, Trautwein C, Liedtke C, Nevzorova YA.

Cell Death Dis. 2017 Oct 26;8(10):e3152. doi: 10.1038/cddis.2017.532.


Alcohol and Hepatocellular Carcinoma: Adding Fuel to the Flame.

Ramadori P, Cubero FJ, Liedtke C, Trautwein C, Nevzorova YA.

Cancers (Basel). 2017 Sep 25;9(10). pii: E130. doi: 10.3390/cancers9100130. Review.


c-MYC-Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease.

Zheng K, Cubero FJ, Nevzorova YA.

Genes (Basel). 2017 Apr 19;8(4). pii: E123. doi: 10.3390/genes8040123. Review.


Anti-tumorigenic and anti-angiogenic effects of natural conifer Abies sibirica terpenoids in vivo and in vitro.

Nevzorova YA, Grossmann J, Trautwein C.

Biomed Pharmacother. 2017 May;89:386-395. doi: 10.1016/j.biopha.2017.02.035. Epub 2017 Feb 28.


Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.

Cubero FJ, Zoubek ME, Hu W, Peng J, Zhao G, Nevzorova YA, Al Masaoudi M, Bechmann LP, Boekschoten MV, Muller M, Preisinger C, Gassler N, Canbay AE, Luedde T, Davis RJ, Liedtke C, Trautwein C.

Gastroenterology. 2016 Apr;150(4):968-81. doi: 10.1053/j.gastro.2015.12.019. Epub 2015 Dec 19.


Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease.

Nevzorova YA, Cubero FJ, Hu W, Hao F, Haas U, Ramadori P, Gassler N, Hoss M, Strnad P, Zimmermann HW, Tacke F, Trautwein C, Liedtke C.

J Hepatol. 2016 Mar;64(3):628-40. doi: 10.1016/j.jhep.2015.11.005. Epub 2015 Nov 11.


Bone marrow-derived c-jun N-terminal kinase-1 (JNK1) mediates liver regeneration.

Schaefer FM, Peng J, Hu W, Drvarov O, Nevzorova YA, Zhao G, Masaoudi MA, Davis RJ, Trautwein C, Cubero FJ.

Biochim Biophys Acta. 2015 Jan;1852(1):137-45. doi: 10.1016/j.bbadis.2014.10.011. Epub 2014 Oct 22.


Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury.

Cubero FJ, Zhao G, Nevzorova YA, Hatting M, Al Masaoudi M, Verdier J, Peng J, Schaefer FM, Hermanns N, Boekschoten MV, Grouls C, Gassler N, Kiessling F, Muller M, Davis RJ, Liedtke C, Trautwein C.

J Hepatol. 2015 Jan;62(1):140-9. doi: 10.1016/j.jhep.2014.08.029. Epub 2014 Aug 27.


The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling.

Borkham-Kamphorst E, Schaffrath C, Van de Leur E, Haas U, Tihaa L, Meurer SK, Nevzorova YA, Liedtke C, Weiskirchen R.

Biochim Biophys Acta. 2014 May;1843(5):902-14. doi: 10.1016/j.bbamcr.2014.01.023. Epub 2014 Jan 31.


Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis.

Zhao G, Hatting M, Nevzorova YA, Peng J, Hu W, Boekschoten MV, Roskams T, Muller M, Gassler N, Liedtke C, Davis RJ, Cubero FJ, Trautwein C.

Gut. 2014 Jul;63(7):1159-72. doi: 10.1136/gutjnl-2013-305507. Epub 2013 Sep 13.


Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice.

Hu W, Nevzorova YA, Haas U, Moro N, Sicinski P, Geng Y, Barbacid M, Trautwein C, Liedtke C.

Hepatology. 2014 Feb;59(2):651-60. doi: 10.1002/hep.26584. Epub 2013 Dec 24.


Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis.

Nevzorova YA, Hu W, Cubero FJ, Haas U, Freimuth J, Tacke F, Trautwein C, Liedtke C.

Biochim Biophys Acta. 2013 Oct;1832(10):1765-75. doi: 10.1016/j.bbadis.2013.06.001. Epub 2013 Jun 12.


Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice.

Nevzorova YA, Bangen JM, Hu W, Haas U, Weiskirchen R, Gassler N, Huss S, Tacke F, Sicinski P, Trautwein C, Liedtke C.

Hepatology. 2012 Sep;56(3):1140-9. doi: 10.1002/hep.25736. Epub 2012 Jul 12.


Sh(i)pping signals protect against Stat3-driven liver cancer.

Nevzorova YA, Liedtke C.

Hepatology. 2012 Jan;55(1):322-4. doi: 10.1002/hep.24742. No abstract available.


Aberrant cell cycle progression and endoreplication in regenerating livers of mice that lack a single E-type cyclin.

Nevzorova YA, Tschaharganeh D, Gassler N, Geng Y, Weiskirchen R, Sicinski P, Trautwein C, Liedtke C.

Gastroenterology. 2009 Aug;137(2):691-703, 703.e1-6. doi: 10.1053/j.gastro.2009.05.003. Epub 2009 May 13.


Expression of a cyclin E1 isoform in mice is correlated with the quiescent cell cycle status of hepatocytes in vivo.

Zschemisch NH, Liedtke C, Dierssen U, Nevzorova YA, Wüstefeld T, Borlak J, Manns MP, Trautwein C.

Hepatology. 2006 Jul;44(1):164-73.


Supplemental Content

Loading ...
Support Center