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Items: 15

1.

Target Identification of the Marine Natural Products Dictyoceratin-A and -C as Selective Growth Inhibitors in Cancer Cells Adapted to Hypoxic Environments.

Kawachi T, Tanaka S, Fukuda A, Sumii Y, Setiawan A, Kotoku N, Kobayashi M, Arai M.

Mar Drugs. 2019 Mar 8;17(3). pii: E163. doi: 10.3390/md17030163.

2.

Asymmetric Electrophilic Difluoromethylthiolation of Indanone-Based β-Keto Esters Using Difluoromethanesulfonyl Hypervalent Iodonium Ylides.

Gondo S, Matsubara O, Chachignon H, Sumii Y, Cahard D, Shibata N.

Molecules. 2019 Jan 9;24(2). pii: E221. doi: 10.3390/molecules24020221.

3.

Design and synthesis of galactose-conjugated fluorinated and non-fluorinated proline oligomers: towards antifreeze molecules.

Sumii Y, Hibino H, Saidalimu I, Kawahara H, Shibata N.

Chem Commun (Camb). 2018 Aug 28;54(70):9749-9752. doi: 10.1039/c8cc05588b.

PMID:
30102305
4.

Stereodivergent trifluoromethylation of N-sulfinylimines by fluoroform with either organic-superbase or organometallic-base.

Punna N, Saito T, Kosobokov M, Tokunaga E, Sumii Y, Shibata N.

Chem Commun (Camb). 2018 Apr 24;54(34):4294-4297. doi: 10.1039/c8cc01526k.

PMID:
29632907
5.

Synthesis of Aryl Triflones through the Trifluoromethanesulfonylation of Benzynes.

Sumii Y, Sugita Y, Tokunaga E, Shibata N.

ChemistryOpen. 2018 Feb 27;7(2):204-211. doi: 10.1002/open.201700204. eCollection 2018 Feb.

6.

Anionic Triflyldiazomethane: Generation and Its Application for Synthesis of Pyrazole-3-triflones via [3 + 2] Cycloaddition Reaction.

Das P, Gondo S, Tokunaga E, Sumii Y, Shibata N.

Org Lett. 2018 Feb 2;20(3):558-561. doi: 10.1021/acs.orglett.7b03664. Epub 2018 Jan 10.

PMID:
29320193
7.

Synthesis of Sulfur Perfluorophenyl Compounds Using a Pentafluorobenzenesulfonyl Hypervalent Iodonium Ylide.

Wang J, Jia S, Okuyama K, Huang Z, Tokunaga E, Sumii Y, Shibata N.

J Org Chem. 2017 Nov 17;82(22):11939-11945. doi: 10.1021/acs.joc.7b01908. Epub 2017 Sep 20.

PMID:
28895393
8.

Structure-Activity Relationship and in Vivo Anti-Tumor Evaluations of Dictyoceratin-A and -C, Hypoxia-Selective Growth Inhibitors from Marine Sponge.

Sumii Y, Kotoku N, Fukuda A, Kawachi T, Arai M, Kobayashi M.

Mar Drugs. 2015 Dec 16;13(12):7419-32. doi: 10.3390/md13127074.

9.

Stereoselective Synthesis of β-Lactam-triflones under Catalyst-Free Conditions.

Huang Z, Wang C, Tokunaga E, Sumii Y, Shibata N.

Org Lett. 2015 Nov 20;17(22):5610-3. doi: 10.1021/acs.orglett.5b02827. Epub 2015 Nov 9.

PMID:
26551769
10.

Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp.

Arai M, Kamiya K, Pruksakorn P, Sumii Y, Kotoku N, Joubert JP, Moodley P, Han C, Shin D, Kobayashi M.

Bioorg Med Chem. 2015 Jul 1;23(13):3534-41. doi: 10.1016/j.bmc.2015.04.033. Epub 2015 Apr 17.

PMID:
25934225
11.

Enantioselective synthesis of dictyoceratin-A (smenospondiol) and -C, hypoxia-selective growth inhibitors from marine sponge.

Sumii Y, Kotoku N, Fukuda A, Kawachi T, Sumii Y, Arai M, Kobayashi M.

Bioorg Med Chem. 2015 Mar 1;23(5):966-75. doi: 10.1016/j.bmc.2015.01.021. Epub 2015 Jan 19.

PMID:
25659617
12.

Xylarianaphthol-1, a novel dinaphthofuran derivative, activates p21 promoter in a p53-independent manner.

Kotoku N, Higashimoto K, Kurioka M, Arai M, Fukuda A, Sumii Y, Sowa Y, Sakai T, Kobayashi M.

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3389-91. doi: 10.1016/j.bmcl.2014.05.083. Epub 2014 Jun 4.

PMID:
24939757
13.

Synthesis and evaluation of effective photoaffinity probe molecule of furospinosulin-1, a hypoxia-selective growth inhibitor.

Kotoku N, Nakata C, Kawachi T, Sato T, Guo XH, Ito A, Sumii Y, Arai M, Kobayashi M.

Bioorg Med Chem. 2014 Apr 1;22(7):2102-12. doi: 10.1016/j.bmc.2014.02.026. Epub 2014 Mar 4.

PMID:
24631363
14.

Creation of readily accessible and orally active analogue of cortistatin a.

Kotoku N, Sumii Y, Hayashi T, Tamura S, Kawachi T, Shiomura S, Arai M, Kobayashi M.

ACS Med Chem Lett. 2012 Jul 10;3(8):673-7. doi: 10.1021/ml300143d. eCollection 2012 Aug 9.

15.

Stereoselective synthesis of core structure of cortistatin A.

Kotoku N, Sumii Y, Kobayashi M.

Org Lett. 2011 Jul 1;13(13):3514-7. doi: 10.1021/ol201327u. Epub 2011 Jun 9.

PMID:
21651309

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