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Items: 1 to 20 of 24


Elastase alters contractility and promotes an inflammatory synthetic phenotype in airway smooth muscle tissues.

Lockett AD, Wu Y, Gunst SJ.

Am J Physiol Lung Cell Mol Physiol. 2018 Apr 1;314(4):L626-L634. doi: 10.1152/ajplung.00334.2017. Epub 2017 Dec 6.


Assessment of an engineered endothelium via single-photon emission computed tomography.

Jiang B, Wu Y, Haney CR, Duan C, Ameer GA.

Biotechnol Bioeng. 2017 Oct;114(10):2371-2378. doi: 10.1002/bit.26342. Epub 2017 Jun 27.


Focal adhesion kinase (FAK) and mechanical stimulation negatively regulate the transition of airway smooth muscle tissues to a synthetic phenotype.

Wu Y, Huang Y, Gunst SJ.

Am J Physiol Lung Cell Mol Physiol. 2016 Nov 1;311(5):L893-L902. doi: 10.1152/ajplung.00299.2016. Epub 2016 Sep 9.


pH-Sensitive Nanomicelles for High-Efficiency siRNA Delivery in Vitro and in Vivo: An Insight into the Design of Polycations with Robust Cytosolic Release.

Zhou J, Wu Y, Wang C, Cheng Q, Han S, Wang X, Zhang J, Deng L, Zhao D, Du L, Cao H, Liang Z, Huang Y, Dong A.

Nano Lett. 2016 Nov 9;16(11):6916-6923. Epub 2016 Oct 17.


Pharmacokinetic Behaviors of Intravenously Administered siRNA in Glandular Tissues.

Huang Y, Cheng Q, Ji JL, Zheng S, Du L, Meng L, Wu Y, Zhao D, Wang X, Lai L, Cao H, Xiao K, Gao S, Liang Z.

Theranostics. 2016 Jun 18;6(10):1528-41. doi: 10.7150/thno.15246. eCollection 2016.


The Promising Nanocarrier for Doxorubicin and siRNA Co-delivery by PDMAEMA-based Amphiphilic Nanomicelles.

Cheng Q, Du L, Meng L, Han S, Wei T, Wang X, Wu Y, Song X, Zhou J, Zheng S, Huang Y, Liang XJ, Cao H, Dong A, Liang Z.

ACS Appl Mater Interfaces. 2016 Feb;8(7):4347-56. doi: 10.1021/acsami.5b11789. Epub 2016 Feb 11.


A Flow-Through Cell Electroporation Device for Rapidly and Efficiently Transfecting Massive Amounts of Cells in vitro and ex vivo.

Zhao D, Huang D, Li Y, Wu M, Zhong W, Cheng Q, Wang X, Wu Y, Zhou X, Wei Z, Li Z, Liang Z.

Sci Rep. 2016 Jan 5;6:18469. doi: 10.1038/srep18469.


A circulating miRNA signature as a diagnostic biomarker for non-invasive early detection of breast cancer.

Zhang L, Xu Y, Jin X, Wang Z, Wu Y, Zhao D, Chen G, Li D, Wang X, Cao H, Xie Y, Liang Z.

Breast Cancer Res Treat. 2015 Nov;154(2):423-34. doi: 10.1007/s10549-015-3591-0. Epub 2015 Oct 17.


Effects of hydrophobic core components in amphiphilic PDMAEMA nanoparticles on siRNA delivery.

Han S, Cheng Q, Wu Y, Zhou J, Long X, Wei T, Huang Y, Zheng S, Zhang J, Deng L, Wang X, Liang XJ, Cao H, Liang Z, Dong A.

Biomaterials. 2015 Apr;48:45-55. doi: 10.1016/j.biomaterials.2015.01.026. Epub 2015 Feb 9.


A novel role for RhoA GTPase in the regulation of airway smooth muscle contraction.

Zhang W, Huang Y, Wu Y, Gunst SJ.

Can J Physiol Pharmacol. 2015 Feb;93(2):129-36. doi: 10.1139/cjpp-2014-0388. Epub 2014 Nov 25. Review.


Doping hydroxylated cationic lipid into PEGylated cerasome boosts in vivo siRNA transfection efficacy.

Li Y, Zheng S, Liang X, Jin Y, Wu Y, Bai H, Liu R, Dai Z, Liang Z, Shi T.

Bioconjug Chem. 2014 Nov 19;25(11):2055-66. doi: 10.1021/bc500414e. Epub 2014 Oct 10.


A flexible microneedle array as low-voltage electroporation electrodes for in vivo DNA and siRNA delivery.

Wei Z, Zheng S, Wang R, Bu X, Ma H, Wu Y, Zhu L, Hu Z, Liang Z, Li Z.

Lab Chip. 2014 Oct 21;14(20):4093-102. doi: 10.1039/c4lc00800f.


Mechanical stimuli and IL-13 interact at integrin adhesion complexes to regulate expression of smooth muscle myosin heavy chain in airway smooth muscle tissue.

Desai LP, Wu Y, Tepper RS, Gunst SJ.

Am J Physiol Lung Cell Mol Physiol. 2011 Sep;301(3):L275-84. doi: 10.1152/ajplung.00043.2011. Epub 2011 Jun 3.


Actin depolymerization factor/cofilin activation regulates actin polymerization and tension development in canine tracheal smooth muscle.

Zhao R, Du L, Huang Y, Wu Y, Gunst SJ.

J Biol Chem. 2008 Dec 26;283(52):36522-31. doi: 10.1074/jbc.M805294200. Epub 2008 Oct 27.


Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue.

Wu Y, Huang Y, Herring BP, Gunst SJ.

Am J Physiol Lung Cell Mol Physiol. 2008 Dec;295(6):L988-97. doi: 10.1152/ajplung.90202.2008. Epub 2008 Sep 19.


Integrin-linked kinase regulates N-WASp-mediated actin polymerization and tension development in tracheal smooth muscle.

Zhang W, Wu Y, Wu C, Gunst SJ.

J Biol Chem. 2007 Nov 23;282(47):34568-80. Epub 2007 Sep 25.


Activation of the Arp2/3 complex by N-WASp is required for actin polymerization and contraction in smooth muscle.

Zhang W, Wu Y, Du L, Tang DD, Gunst SJ.

Am J Physiol Cell Physiol. 2005 May;288(5):C1145-60. Epub 2004 Dec 29.


Correlation between VEGF and HIF-1alpha expression in human oral squamous cell carcinoma.

Mohamed KM, Le A, Duong H, Wu Y, Zhang Q, Messadi DV.

Exp Mol Pathol. 2004 Apr;76(2):143-52.


Crosstalk of hypoxia-mediated signaling pathways in upregulating plasminogen activator inhibitor-1 expression in keloid fibroblasts.

Zhang Q, Wu Y, Chau CH, Ann DK, Bertolami CN, Le AD.

J Cell Physiol. 2004 Apr;199(1):89-97.


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