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Items: 11


Exploring isoxazoles and pyrrolidinones decorated with the 4,6-dimethoxy-1,3,5-triazine unit as human farnesyltransferase inhibitors.

Lucescu L, Ghinet A, Shova S, Magnez R, Thuru X, Farce A, Rigo B, Belei D, Dubois J, Bîcu E.

Arch Pharm (Weinheim). 2019 May;352(5):e1800227. doi: 10.1002/ardp.201800227. Epub 2019 Apr 4.


Isolation and characterization of two canine melanoma cell lines: new models for comparative oncology.

Segaoula Z, Primot A, Lepretre F, Hedan B, Bouchaert E, Minier K, Marescaux L, Serres F, Galiègue-Zouitina S, André C, Quesnel B, Thuru X, Tierny D.

BMC Cancer. 2018 Dec 4;18(1):1219. doi: 10.1186/s12885-018-5114-y.


Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.

Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, Guichou JF, Drucbert AS, Foulon C, Magnez R, Thuru X, Corvaisier M, Huet G, Chavatte P, Melnyk P, Bailly F, Cotelle P.

Cancers (Basel). 2018 May 8;10(5). pii: E140. doi: 10.3390/cancers10050140.


PD-1/PD-L1 binding studies using microscale thermophoresis.

Magnez R, Thiroux B, Taront S, Segaoula Z, Quesnel B, Thuru X.

Sci Rep. 2017 Dec 15;7(1):17623. doi: 10.1038/s41598-017-17963-1.


Synthesis and Biological Evaluation of N-[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity.

Segaoula Z, Leclercq J, Verones V, Flouquet N, Lecoeur M, Ach L, Renault N, Barczyk A, Melnyk P, Berthelot P, Thuru X, Lebegue N.

J Med Chem. 2016 Sep 22;59(18):8422-40. doi: 10.1021/acs.jmedchem.6b00847. Epub 2016 Aug 30.


Phase I Clinical Pharmacology Study of F14512, a New Polyamine-Vectorized Anticancer Drug, in Naturally Occurring Canine Lymphoma.

Tierny D, Serres F, Segaoula Z, Bemelmans I, Bouchaert E, Pétain A, Brel V, Couffin S, Marchal T, Nguyen L, Thuru X, Ferré P, Guilbaud N, Gomes B.

Clin Cancer Res. 2015 Dec 1;21(23):5314-23. doi: 10.1158/1078-0432.CCR-14-3174. Epub 2015 Jul 13.


Synthesis and biological evaluation of phenstatin metabolites.

Ghinet A, Rigo B, Hénichart JP, Le Broc-Ryckewaert D, Pommery J, Pommery N, Thuru X, Quesnel B, Gautret P.

Bioorg Med Chem. 2011 Oct 15;19(20):6042-54. doi: 10.1016/j.bmc.2011.08.047. Epub 2011 Aug 27.


Colonization of mice by Candida albicans is promoted by chemically induced colitis and augments inflammatory responses through galectin-3.

Jawhara S, Thuru X, Standaert-Vitse A, Jouault T, Mordon S, Sendid B, Desreumaux P, Poulain D.

J Infect Dis. 2008 Apr 1;197(7):972-80. doi: 10.1086/528990.


micro-Opioid receptor activation prevents acute hepatic inflammation and cell death.

Chakass D, Philippe D, Erdual E, Dharancy S, Malapel M, Dubuquoy C, Thuru X, Gay J, Gaveriaux-Ruff C, Dubus P, Mathurin P, Kieffer BL, Desreumaux P, Chamaillard M.

Gut. 2007 Jul;56(7):974-81. Epub 2007 Feb 13.


Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors.

Rousseaux C, Thuru X, Gelot A, Barnich N, Neut C, Dubuquoy L, Dubuquoy C, Merour E, Geboes K, Chamaillard M, Ouwehand A, Leyer G, Carcano D, Colombel JF, Ardid D, Desreumaux P.

Nat Med. 2007 Jan;13(1):35-7. Epub 2006 Dec 10.


[Control of secretory diarrhea and colorectal cancer growth by cannabinoids in the gut].

Desreumaux P, Thuru X, Philippe D.

Gastroenterol Clin Biol. 2004 Jan;28(1):97. French. No abstract available.

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