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The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function.

Brown A, Schuetz D, Han Y, Daria D, Nattamai KJ, Eiwen K, Sakk V, Pospiech J, Saller T, van Zant G, Wagner W, Geiger H.

Haematologica. 2019 May 9. pii: haematol.2018.213009. doi: 10.3324/haematol.2018.213009. [Epub ahead of print]


The Link Between Epigenetic Clocks for Aging and Senescence.

Wagner W.

Front Genet. 2019 Apr 3;10:303. doi: 10.3389/fgene.2019.00303. eCollection 2019. Review.


Supramolecular Polymorphism in One-Dimensional Self-Assembly by Kinetic Pathway Control.

Wehner M, Röhr MIS, Bühler M, Stepanenko V, Wagner W, Würthner F.

J Am Chem Soc. 2019 Apr 10;141(14):6092-6107. doi: 10.1021/jacs.9b02046. Epub 2019 Mar 29.


The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell-derived sensory neurons of erythromelalgia patients.

Meents JE, Bressan E, Sontag S, Foerster A, Hautvast P, Rösseler C, Hampl M, Schüler H, Goetzke R, Le TKC, Kleggetveit IP, Le Cann K, Kerth C, Rush AM, Rogers M, Kohl Z, Schmelz M, Wagner W, Jørum E, Namer B, Winner B, Zenke M, Lampert A.

Pain. 2019 Jun;160(6):1327-1341. doi: 10.1097/j.pain.0000000000001511.


Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells.

Cypris O, Frobel J, Rai S, Franzen J, Sontag S, Goetzke R, Szymanski de Toledo MA, Zenke M, Wagner W.

Clin Epigenetics. 2019 Feb 4;11(1):19. doi: 10.1186/s13148-019-0617-1.


Tracking of myeloid malignancies by targeted analysis of successive DNA methylation at neighboring CG dinucleotides.

Eipel M, Božić T, Mies A, Beier F, Jost E, Brümmendorf TH, Platzbecker U, Wagner W.

Haematologica. 2019 Jan 31. pii: haematol.2018.209734. doi: 10.3324/haematol.2018.209734. [Epub ahead of print]


Response to Letter to the Editor: Epigenetic Aging in Osteoporosis.

Jakob F, Ebert R, Fernandez-Rebollo E, Bischof O, Wagner W.

J Bone Miner Res. 2018 Oct;33(10):1904-1905. doi: 10.1002/jbmr.3569. Epub 2018 Sep 14. No abstract available.


Variants of DNMT3A cause transcript-specific DNA methylation patterns and affect hematopoiesis.

Božić T, Frobel J, Raic A, Ticconi F, Kuo CC, Heilmann-Heimbach S, Goecke TW, Zenke M, Jost E, Costa IG, Wagner W.

Life Sci Alliance. 2018 Dec 13;1(6):e201800153. doi: 10.26508/lsa.201800153. eCollection 2018 Dec.


Association of facial ageing with DNA methylation and epigenetic age predictions.

Marioni RE, Belsky DW, Deary IJ, Wagner W.

Clin Epigenetics. 2018 Nov 8;10(1):140. doi: 10.1186/s13148-018-0572-2.


A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation.

Sheng C, Jungverdorben J, Wiethoff H, Lin Q, Flitsch LJ, Eckert D, Hebisch M, Fischer J, Kesavan J, Weykopf B, Schneider L, Holtkamp D, Beck H, Till A, Wüllner U, Ziller MJ, Wagner W, Peitz M, Brüstle O.

Nat Commun. 2018 Oct 2;9(1):4047. doi: 10.1038/s41467-018-06398-5.


Cancer and the arts: a Pacifist's Guide to the War on Cancer.

Wagner W.

ESMO Open. 2018 Sep 8;3(6):e000430. doi: 10.1136/esmoopen-2018-000430. eCollection 2018. No abstract available.


LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat.

Schmidt E, Dhaouadi I, Gaziano I, Oliverio M, Klemm P, Awazawa M, Mitterer G, Fernandez-Rebollo E, Pradas-Juni M, Wagner W, Hammerschmidt P, Loureiro R, Kiefer C, Hansmeier NR, Khani S, Bergami M, Heine M, Ntini E, Frommolt P, Zentis P, Ørom UA, Heeren J, Blüher M, Bilban M, Kornfeld JW.

Nat Commun. 2018 Sep 6;9(1):3622. doi: 10.1038/s41467-018-05933-8.


Epigenetic age-predictor for mice based on three CpG sites.

Han Y, Eipel M, Franzen J, Sakk V, Dethmers-Ausema B, Yndriago L, Izeta A, de Haan G, Geiger H, Wagner W.

Elife. 2018 Aug 24;7. pii: e37462. doi: 10.7554/eLife.37462.


Coupled Cooperative Supramolecular Polymerization: A New Model Applied to the Competing Aggregation Pathways of an Amphiphilic aza-BODIPY Dye into Spherical and Rod-Like Aggregates.

Liu Y, Zhang Y, Fennel F, Wagner W, Würthner F, Chen Y, Chen Z.

Chemistry. 2018 Nov 2;24(61):16388-16394. doi: 10.1002/chem.201803336. Epub 2018 Oct 11.


Interrupted reprogramming into induced pluripotent stem cells does not rejuvenate human mesenchymal stromal cells.

Göbel C, Goetzke R, Eggermann T, Wagner W.

Sci Rep. 2018 Aug 3;8(1):11676. doi: 10.1038/s41598-018-30069-6.


Creation of a myosin Va-TAP-tagged mouse and identification of potential myosin Va-interacting proteins in the cerebellum.

Alexander CJ, Wagner W, Copeland NG, Jenkins NA, Hammer JA.

Cytoskeleton (Hoboken). 2018 Sep;75(9):395-409. doi: 10.1002/cm.21474.


Enhanced expression of thioredoxin-interacting-protein regulates oxidative DNA damage and aging.

Oberacker T, Bajorat J, Ziola S, Schroeder A, Röth D, Kastl L, Edgar BA, Wagner W, Gülow K, Krammer PH.

FEBS Lett. 2018 Jul;592(13):2297-2307. doi: 10.1002/1873-3468.13156. Epub 2018 Jun 27.


Serum of myeloproliferative neoplasms stimulates hematopoietic stem and progenitor cells.

Lubberich RK, Walenda T, Goecke TW, Strathmann K, Isfort S, Brümmendorf TH, Koschmieder S, Wagner W.

PLoS One. 2018 May 31;13(5):e0197233. doi: 10.1371/journal.pone.0197233. eCollection 2018.


Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice.

Frobel J, Rahmig S, Franzen J, Waskow C, Wagner W.

Clin Epigenetics. 2018 May 22;10:67. doi: 10.1186/s13148-018-0499-7. eCollection 2018.


Why the impact of mechanical stimuli on stem cells remains a challenge.

Goetzke R, Sechi A, De Laporte L, Neuss S, Wagner W.

Cell Mol Life Sci. 2018 Sep;75(18):3297-3312. doi: 10.1007/s00018-018-2830-z. Epub 2018 May 4. Review.


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