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Items: 1 to 20 of 236

1.

Nature's combinatorial biosynthesis produces vatiamides A-F.

Moss NA, Seiler G, Leão TF, Castro-Falcón G, Gerwick L, Hughes CC, Gerwick WH.

Angew Chem Int Ed Engl. 2019 May 9. doi: 10.1002/anie.201902571. [Epub ahead of print]

PMID:
31071229
2.

Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién.

Tayler NM, Boya CA, Herrera L, Moy J, Ng M, Pineda L, Almanza A, Rosero S, Coronado LM, Correa R, Santamaría R, Caballero Z, Durant-Archibold AA, Tidgewell KJ, Balunas MJ, Gerwick WH, Spadafora A, Gutiérrez M, Spadafora C.

PLoS One. 2019 Apr 2;14(4):e0214193. doi: 10.1371/journal.pone.0214193. eCollection 2019.

3.

Marine natural products as potential anti-tubercular agents.

Hou XM, Wang CY, Gerwick WH, Shao CL.

Eur J Med Chem. 2019 Mar 1;165:273-292. doi: 10.1016/j.ejmech.2019.01.026. Epub 2019 Jan 14. Review.

PMID:
30685527
4.

Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp.

Caro-Diaz EJE, Valeriote FA, Gerwick WH.

Org Lett. 2019 Feb 1;21(3):793-796. doi: 10.1021/acs.orglett.8b04050. Epub 2019 Jan 23.

PMID:
30673235
5.

1-Octen-3-ol, a self-stimulating oxylipin messenger, can prime and induce defense of marine alga.

Chen H, Yang R, Chen J, Luo Q, Cui X, Yan X, Gerwick WH.

BMC Plant Biol. 2019 Jan 22;19(1):37. doi: 10.1186/s12870-019-1642-0.

6.

Integrated Genomic and Metabolomic Approach to the Discovery of Potential Anti-Quorum Sensing Natural Products from Microbes Associated with Marine Samples from Singapore.

Ong JFM, Goh HC, Lim SC, Pang LM, Chin JSF, Tan KS, Liang ZX, Yang L, Glukhov E, Gerwick WH, Tan LT.

Mar Drugs. 2019 Jan 21;17(1). pii: E72. doi: 10.3390/md17010072.

7.

Dragocins A-D, Structurally Intriguing Cytotoxic Metabolites from a Panamanian Marine Cyanobacterium.

Choi H, Engene N, Byrum T, Hwang S, Oh DC, Gerwick WH.

Org Lett. 2019 Jan 4;21(1):266-270. doi: 10.1021/acs.orglett.8b03712. Epub 2018 Dec 19.

PMID:
30566359
8.

MS/MS-Based Molecular Networking Approach for the Detection of Aplysiatoxin-Related Compounds in Environmental Marine Cyanobacteria.

Ding CYG, Pang LM, Liang ZX, Goh KKK, Glukhov E, Gerwick WH, Tan LT.

Mar Drugs. 2018 Dec 13;16(12). pii: E505. doi: 10.3390/md16120505.

9.

Structural Basis of Polyketide Synthase O-Methylation.

Skiba MA, Bivins MM, Schultz JR, Bernard SM, Fiers WD, Dan Q, Kulkarni S, Wipf P, Gerwick WH, Sherman DH, Aldrich CC, Smith JL.

ACS Chem Biol. 2018 Dec 21;13(12):3221-3228. doi: 10.1021/acschembio.8b00687. Epub 2018 Dec 3.

PMID:
30489068
10.

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):248-249. doi: 10.1039/c8np90041h. Epub 2018 Nov 23.

11.

Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta.

Moss NA, Leão T, Rankin MR, McCullough TM, Qu P, Korobeynikov A, Smith JL, Gerwick L, Gerwick WH.

ACS Chem Biol. 2018 Dec 21;13(12):3385-3395. doi: 10.1021/acschembio.8b00910. Epub 2018 Dec 3.

PMID:
30444349
12.

Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents.

Almaliti J, Miller B, Pietraszkiewicz H, Glukhov E, Naman CB, Kline T, Hanson J, Li X, Zhou S, Valeriote FA, Gerwick WH.

Eur J Med Chem. 2019 Jan 1;161:416-432. doi: 10.1016/j.ejmech.2018.10.024. Epub 2018 Oct 15.

PMID:
30384045
13.

The Metabolome of a Cyanobacterial Bloom Visualized by MS/MS-Based Molecular Networking Reveals New Neurotoxic Smenamide Analogs (C, D, and E).

Via CW, Glukhov E, Costa S, Zimba PV, Moeller PDR, Gerwick WH, Bertin MJ.

Front Chem. 2018 Jul 26;6:316. doi: 10.3389/fchem.2018.00316. eCollection 2018.

14.

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):35-107. doi: 10.1039/c7np00064b. Epub 2018 Jul 13. Erratum in: Nat Prod Rep. 2018 Nov 23;:.

15.

Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease.

O'Rourke A, Kremb S, Duggan BM, Sioud S, Kharbatia N, Raji M, Emwas AH, Gerwick WH, Voolstra CR.

Molecules. 2018 Jun 18;23(6). pii: E1472. doi: 10.3390/molecules23061472.

16.

Corrigendum to: "Alkaloids from Corydalis decumbens suppress neuronal excitability in primary cultures of mouse neocortical neurons" [Phytochemistry (2018) 150 85-92].

Huang Q, Chen J, Zhang W, Zhou B, Zhang C, Gerwick WH, Cao Z.

Phytochemistry. 2018 Oct;154:106-107. doi: 10.1016/j.phytochem.2018.06.004. Epub 2018 Jun 13. No abstract available.

PMID:
29907440
17.

Collection, Culturing, and Genome Analyses of Tropical Marine Filamentous Benthic Cyanobacteria.

Moss NA, Leao T, Glukhov E, Gerwick L, Gerwick WH.

Methods Enzymol. 2018;604:3-43. doi: 10.1016/bs.mie.2018.02.014. Epub 2018 Apr 27.

PMID:
29779657
18.

Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group.

Kristoffersen V, Rämä T, Isaksson J, Andersen JH, Gerwick WH, Hansen E.

Mar Drugs. 2018 May 14;16(5). pii: E163. doi: 10.3390/md16050163.

19.

Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module.

Skiba MA, Sikkema AP, Moss NA, Lowell AN, Su M, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL.

ACS Chem Biol. 2018 Jun 15;13(6):1640-1650. doi: 10.1021/acschembio.8b00252. Epub 2018 May 8.

PMID:
29701944
20.

Eckmaxol, a Phlorotannin Extracted from Ecklonia maxima, Produces Anti-β-amyloid Oligomer Neuroprotective Effects Possibly via Directly Acting on Glycogen Synthase Kinase 3β.

Wang J, Zheng J, Huang C, Zhao J, Lin J, Zhou X, Naman CB, Wang N, Gerwick WH, Wang Q, Yan X, Cui W, He S.

ACS Chem Neurosci. 2018 Jun 20;9(6):1349-1356. doi: 10.1021/acschemneuro.7b00527. Epub 2018 Apr 10.

PMID:
29608860

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