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Items: 1 to 20 of 109

1.

A new mouse model for noninvasive fluorescence-based monitoring of mitochondrial UCP1 expression.

Kawarasaki S, Kuwata H, Sawazaki H, Sakamoto T, Nitta T, Kim CS, Jheng HF, Takahashi H, Nomura W, Ara T, Takahashi N, Tomita K, Yu R, Kawada T, Goto T.

FEBS Lett. 2019 May 10. doi: 10.1002/1873-3468.13430. [Epub ahead of print]

PMID:
31074834
2.

Soy hydrolysate enhances the isoproterenol-stimulated lipolytic pathway through an increase in β-adrenergic receptor expression in adipocytes.

Ng SP, Nomura W, Mohri S, Takahashi H, Jheng HF, Ara T, Nagai H, Ito T, Kawada T, Goto T.

Biosci Biotechnol Biochem. 2019 May 2:1-8. doi: 10.1080/09168451.2019.1611413. [Epub ahead of print]

PMID:
31045477
3.

C34 Dimeric Derivatives Utilizing Disulfide Bridges as Novel HIV-1 Fusion Inhibitors.

Kobayakawa T, Ebihara K, Honda Y, Fujino M, Nomura W, Yamamoto N, Murakami T, Tamamura H.

Chembiochem. 2019 Apr 22. doi: 10.1002/cbic.201900187. [Epub ahead of print]

PMID:
31012222
4.

Development of a NanoBRET-Based Sensitive Screening Method for CXCR4 Ligands.

Sakyiamah MM, Nomura W, Kobayakawa T, Tamamura H.

Bioconjug Chem. 2019 May 15;30(5):1442-1450. doi: 10.1021/acs.bioconjchem.9b00182. Epub 2019 Apr 11.

PMID:
30973227
5.

Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands.

Sakyiamah MM, Kobayakawa T, Fujino M, Konno M, Narumi T, Tanaka T, Nomura W, Yamamoto N, Murakami T, Tamamura H.

Bioorg Med Chem. 2019 Mar 15;27(6):1130-1138. doi: 10.1016/j.bmc.2019.02.013. Epub 2019 Feb 6.

PMID:
30772128
6.

Endoplasmic Reticulum Stress Impaired Uncoupling Protein 1 Expression via the Suppression of Peroxisome Proliferator-Activated Receptor γ Binding Activity in Mice Beige Adipocytes.

Yuliana A, Daijo A, Jheng HF, Kwon J, Nomura W, Takahashi H, Ara T, Kawada T, Goto T.

Int J Mol Sci. 2019 Jan 11;20(2). pii: E274. doi: 10.3390/ijms20020274.

7.

Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C-induced HIV latency reversal.

Matsuda K, Kobayakawa T, Tsuchiya K, Hattori SI, Nomura W, Gatanaga H, Yoshimura K, Oka S, Endo Y, Tamamura H, Mitsuya H, Maeda K.

J Biol Chem. 2019 Jan 4;294(1):116-129. doi: 10.1074/jbc.RA118.005798. Epub 2018 Nov 9.

8.

The dipeptidyl peptidase-4 (DPP-4) inhibitor teneligliptin enhances brown adipose tissue function, thereby preventing obesity in mice.

Takeda K, Sawazaki H, Takahashi H, Yeh YS, Jheng HF, Nomura W, Ara T, Takahashi N, Seno S, Osato N, Matsuda H, Kawada T, Goto T.

FEBS Open Bio. 2018 Sep 19;8(11):1782-1793. doi: 10.1002/2211-5463.12498. eCollection 2018 Nov.

9.

The Mevalonate Pathway Is Indispensable for Adipocyte Survival.

Yeh YS, Jheng HF, Iwase M, Kim M, Mohri S, Kwon J, Kawarasaki S, Li Y, Takahashi H, Ara T, Nomura W, Kawada T, Goto T.

iScience. 2018 Nov 30;9:175-191. doi: 10.1016/j.isci.2018.10.019. Epub 2018 Oct 21.

10.

Inhibition of EGFR Activation by Bivalent Ligands Based on a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.

Toyama K, Kobayakawa T, Nomura W, Tamamura H.

Chem Pharm Bull (Tokyo). 2018;66(11):1083-1089. doi: 10.1248/cpb.c18-00539.

11.

Efficient and Orthogonal Transcription Regulation by Chemically Inducible Artificial Transcription Factors.

Nomura W, Matsumoto D, Sugii T, Kobayakawa T, Tamamura H.

Biochemistry. 2018 Nov 13;57(45):6452-6459. doi: 10.1021/acs.biochem.8b00741. Epub 2018 Nov 2.

PMID:
30366497
12.

Chemogenetic Approach Using Ni(II) Complex-Agonist Conjugates Allows Selective Activation of Class A G-Protein-Coupled Receptors.

Kubota R, Nomura W, Iwasaka T, Ojima K, Kiyonaka S, Hamachi I.

ACS Cent Sci. 2018 Sep 26;4(9):1211-1221. doi: 10.1021/acscentsci.8b00390. Epub 2018 Aug 24.

13.

β-adrenergic Receptor Stimulation Revealed a Novel Regulatory Pathway via Suppressing Histone Deacetylase 3 to Induce Uncoupling Protein 1 Expression in Mice Beige Adipocyte.

Yuliana A, Jheng HF, Kawarasaki S, Nomura W, Takahashi H, Ara T, Kawada T, Goto T.

Int J Mol Sci. 2018 Aug 17;19(8). pii: E2436. doi: 10.3390/ijms19082436.

14.

Development of Toolboxes for Precision Genome/Epigenome Editing and Imaging of Epigenetics.

Nomura W.

Chem Rec. 2018 Dec;18(12):1717-1726. doi: 10.1002/tcr.201800036. Epub 2018 Aug 1. Review.

PMID:
30066981
15.
16.

Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.

Toyama K, Nomura W, Kobayakawa T, Tamamura H.

Bioconjug Chem. 2018 Jun 20;29(6):2050-2057. doi: 10.1021/acs.bioconjchem.8b00250. Epub 2018 May 31.

PMID:
29763296
17.

Synthesis of a Chloroalkene Dipeptide Isostere-Containing Peptidomimetic and Its Biological Application.

Kobayakawa T, Matsuzaki Y, Hozumi K, Nomura W, Nomizu M, Tamamura H.

ACS Med Chem Lett. 2017 Dec 27;9(1):6-10. doi: 10.1021/acsmedchemlett.7b00234. eCollection 2018 Jan 11.

18.

iML1515, a knowledgebase that computes Escherichia coli traits.

Monk JM, Lloyd CJ, Brunk E, Mih N, Sastry A, King Z, Takeuchi R, Nomura W, Zhang Z, Mori H, Feist AM, Palsson BO.

Nat Biotechnol. 2017 Oct 11;35(10):904-908. doi: 10.1038/nbt.3956. No abstract available.

19.

Creation of Functional Molecules Based on Biomolecular Interactions; Development toward Chemical Biology.

Nomura W.

Yakugaku Zasshi. 2017;137(10):1223-1231. doi: 10.1248/yakushi.17-00125. Review. Japanese.

20.

Phosphatidylinositol 3,5-bisphosphate is involved in methylglyoxal-induced activation of the Mpk1 mitogen-activated protein kinase cascade in Saccharomyces cerevisiae.

Nomura W, Maeta K, Inoue Y.

J Biol Chem. 2017 Sep 8;292(36):15039-15048. doi: 10.1074/jbc.M117.791590. Epub 2017 Jul 25.

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