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Items: 1 to 20 of 46


DPS-2: A Novel Dual MEK/ERK and PI3K/AKT Pathway Inhibitor with Powerful Ex Vivo and In Vivo Anticancer Properties.

Goulielmaki M, Assimomytis N, Rozanc J, Taki E, Christodoulou I, Alexopoulos LG, Zoumpourlis V, Pintzas A, Papahatjis D.

Transl Oncol. 2019 May 13;12(7):932-950. doi: 10.1016/j.tranon.2019.04.005. [Epub ahead of print]


Biochemical pathways mediated by KLK6 protease in breast cancer.

Pampalakis G, Zingkou E, Sidiropoulos KG, Diamandis EP, Zoumpourlis V, Yousef GM, Sotiropoulou G.

Mol Oncol. 2019 Apr 13. doi: 10.1002/1878-0261.12493. [Epub ahead of print]


Mesenchymal stem cells in preclinical cancer cytotherapy: a systematic review.

Christodoulou I, Goulielmaki M, Devetzi M, Panagiotidis M, Koliakos G, Zoumpourlis V.

Stem Cell Res Ther. 2018 Dec 7;9(1):336. doi: 10.1186/s13287-018-1078-8.


Canagliflozin-loaded magnetic nanoparticles as potential treatment of hypoxic tumors in combination with radiotherapy.

Angelopoulou A, Kolokithas-Ntoukas A, Papaioannou L, Kakazanis Z, Khoury N, Zoumpourlis V, Papatheodorou S, Kardamakis D, Bakandritsos A, Hatziantoniou S, Avgoustakis K.

Nanomedicine (Lond). 2018 Oct;13(19):2435-2454. doi: 10.2217/nnm-2018-0145. Epub 2018 Oct 12.


Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer.

Vlahopoulos S, Adamaki M, Khoury N, Zoumpourlis V, Boldogh I.

Pharmacol Ther. 2019 Feb;194:59-72. doi: 10.1016/j.pharmthera.2018.09.004. Epub 2018 Sep 19. Review.


KLK6 protease accelerates skin tumor formation and progression.

Khoury N, Zingkou E, Pampalakis G, Sofopoulos M, Zoumpourlis V, Sotiropoulou G.

Carcinogenesis. 2018 Dec 31;39(12):1529-1536. doi: 10.1093/carcin/bgy110.


CRISPR therapeutic tools for complex genetic disorders and cancer (Review).

Baliou S, Adamaki M, Kyriakopoulos AM, Spandidos DA, Panayiotidis M, Christodoulou I, Zoumpourlis V.

Int J Oncol. 2018 Aug;53(2):443-468. doi: 10.3892/ijo.2018.4434. Epub 2018 Jun 6. Review.


Selective cytotoxicity of the herbal substance acteoside against tumor cells and its mechanistic insights.

Cheimonidi C, Samara P, Polychronopoulos P, Tsakiri EN, Nikou T, Myrianthopoulos V, Sakellaropoulos T, Zoumpourlis V, Mikros E, Papassideri I, Argyropoulou A, Halabalaki M, Alexopoulos LG, Skaltsounis AL, Tsitsilonis OE, Aligiannis NN, Trougakos IP.

Redox Biol. 2018 Jun;16:169-178. doi: 10.1016/j.redox.2018.02.015. Epub 2018 Mar 1.


Genetically‑modified stem cells in treatment of human diseases: Tissue kallikrein (KLK1)‑based targeted therapy (Review).

Devetzi M, Goulielmaki M, Khoury N, Spandidos DA, Sotiropoulou G, Christodoulou I, Zoumpourlis V.

Int J Mol Med. 2018 Mar;41(3):1177-1186. doi: 10.3892/ijmm.2018.3361. Epub 2018 Jan 3. Review.


Role of the CRISPR system in controlling gene transcription and monitoring cell fate (Review).

Baliou S, Adamaki M, Kyriakopoulos AM, Spandidos DA, Panayiotidis M, Christodoulou I, Zoumpourlis V.

Mol Med Rep. 2018 Jan;17(1):1421-1427. doi: 10.3892/mmr.2017.8099. Epub 2017 Nov 16. Review.


A Triphenylphosphonium-Functionalized Mitochondriotropic Nanocarrier for Efficient Co-Delivery of Doxorubicin and Chloroquine and Enhanced Antineoplastic Activity.

Panagiotaki KN, Sideratou Z, Vlahopoulos SA, Paravatou-Petsotas M, Zachariadis M, Khoury N, Zoumpourlis V, Tsiourvas D.

Pharmaceuticals (Basel). 2017 Nov 21;10(4). pii: E91. doi: 10.3390/ph10040091.


The Ideological Frame of the Genetic Basis of Cancer: The Important Role of miRNAs.

Zoumpourlis V, Skourti E, Goulielmaki M, Vlahopoulos S, Christodoulou I.

Crit Rev Oncog. 2017;22(3-4):303-311. doi: 10.1615/CritRevOncog.2017024535. Review.


Homeobox Gene Involvement in Normal Hematopoiesis and in the Pathogenesis of Childhood Leukemias.

Adamaki M, Goulielmaki M, Christodoulou I, Vlahopoulos S, Zoumpourlis V.

Crit Rev Oncog. 2017;22(3-4):157-185. doi: 10.1615/CritRevOncog.2017024465. Review.


Unravelling a p73-regulated network: The role of a novel p73-dependent target, MIR3158, in cancer cell migration and invasiveness.

Galtsidis S, Logotheti S, Pavlopoulou A, Zampetidis CP, Papachristopoulou G, Scorilas A, Vojtesek B, Gorgoulis V, Zoumpourlis V.

Cancer Lett. 2017 Mar 1;388:96-106. doi: 10.1016/j.canlet.2016.11.036. Epub 2016 Dec 3.


Synthesis, characterization and in vivo evaluation of a magnetic cisplatin delivery nanosystem based on PMAA-graft-PEG copolymers.

Voulgari E, Bakandritsos A, Galtsidis S, Zoumpourlis V, Burke BP, Clemente GS, Cawthorne C, Archibald SJ, Tuček J, Zbořil R, Kantarelou V, Karydas AG, Avgoustakis K.

J Control Release. 2016 Dec 10;243:342-356. doi: 10.1016/j.jconrel.2016.10.021. Epub 2016 Oct 26.


ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells.

Nekulova M, Holcakova J, Gu X, Hrabal V, Galtsidis S, Orzol P, Liu Y, Logotheti S, Zoumpourlis V, Nylander K, Coates PJ, Vojtesek B.

BMC Cancer. 2016 Oct 10;16(1):782.


Cornus mas L. (cornelian cherry), an important European and Asian traditional food and medicine: Ethnomedicine, phytochemistry and pharmacology for its commercial utilization in drug industry.

Dinda B, Kyriakopoulos AM, Dinda S, Zoumpourlis V, Thomaidis NS, Velegraki A, Markopoulos C, Dinda M.

J Ethnopharmacol. 2016 Dec 4;193:670-690. doi: 10.1016/j.jep.2016.09.042. Epub 2016 Oct 2. Review.


N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor.

Logotheti S, Khoury N, Vlahopoulos SA, Skourti E, Papaevangeliou D, Liloglou T, Gorgoulis V, Budunova I, Kyriakopoulos AM, Zoumpourlis V.

Transl Res. 2016 Jul;173:58-73.e2. doi: 10.1016/j.trsl.2016.03.009. Epub 2016 Mar 21.


Progression of mouse skin carcinogenesis is associated with the orchestrated deregulation of mir-200 family members, mir-205 and their common targets.

Skourti E, Logotheti S, Kontos CK, Pavlopoulou A, Dimoragka PT, Trougakos IP, Gorgoulis V, Scorilas A, Michalopoulos I, Zoumpourlis V.

Mol Carcinog. 2016 Aug;55(8):1229-42. doi: 10.1002/mc.22365. Epub 2015 Aug 27.


Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer.

Velimezi G, Liontos M, Vougas K, Roumeliotis T, Bartkova J, Sideridou M, Dereli-Oz A, Kocylowski M, Pateras IS, Evangelou K, Kotsinas A, Orsolic I, Bursac S, Cokaric-Brdovcak M, Zoumpourlis V, Kletsas D, Papafotiou G, Klinakis A, Volarevic S, Gu W, Bartek J, Halazonetis TD, Gorgoulis VG.

Nat Cell Biol. 2013 Aug;15(8):967-77. doi: 10.1038/ncb2795. Epub 2013 Jul 14. Erratum in: Nat Cell Biol. 2013 Oct;15(10):1260.


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