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Items: 1 to 20 of 45


The emerging role of sorting nexins in cardiovascular diseases.

Yang J, Villar VAM, Rozyyev S, Jose PA, Zeng C.

Clin Sci (Lond). 2019 Mar 15;133(5):723-737. doi: 10.1042/CS20190034. Print 2019 Mar 29. Review.


Genetic polymorphisms associated with reactive oxygen species and blood pressure regulation.

Cuevas S, Villar VAM, Jose PA.

Pharmacogenomics J. 2019 Feb 6. doi: 10.1038/s41397-019-0082-4. [Epub ahead of print]


Non-additive effects of ACVR2A in preeclampsia in a Philippine population.

Amosco MD, Tavera GR, Villar VAM, Naniong JMA, David-Bustamante LMG, Williams SM, Jose PA, Palmes-Saloma CP.

BMC Pregnancy Childbirth. 2019 Jan 8;19(1):11. doi: 10.1186/s12884-018-2152-z.


Dopamine D2 receptor upregulates leptin and IL-6 in adipocytes.

Wang X, Villar VA, Tiu A, Upadhyay KK, Cuevas S.

J Lipid Res. 2018 Apr;59(4):607-614. doi: 10.1194/jlr.M081000. Epub 2018 Feb 22.


Loss of renal SNX5 results in impaired IDE activity and insulin resistance in mice.

Li F, Yang J, Villar VAM, Asico LD, Ma X, Armando I, Sanada H, Yoneda M, Felder RA, Jose PA, Wang X.

Diabetologia. 2018 Mar;61(3):727-737. doi: 10.1007/s00125-017-4482-1. Epub 2017 Oct 28.


Primary Pediatric Hypertension: Current Understanding and Emerging Concepts.

Tiu AC, Bishop MD, Asico LD, Jose PA, Villar VAM.

Curr Hypertens Rep. 2017 Sep;19(9):70. doi: 10.1007/s11906-017-0768-4. Review.


Increased renal oxidative stress in salt-sensitive human GRK4γ486V transgenic mice.

Diao Z, Asico LD, Villar VAM, Zheng X, Cuevas S, Armando I, Jose PA, Wang X.

Free Radic Biol Med. 2017 May;106:80-90. doi: 10.1016/j.freeradbiomed.2017.02.021. Epub 2017 Feb 9.


VEGF-A and VEGFR1 SNPs associate with preeclampsia in a Philippine population.

Amosco MD, Villar VA, Naniong JM, David-Bustamante LM, Jose PA, Palmes-Saloma CP.

Clin Exp Hypertens. 2016;38(7):578-585. Epub 2016 Sep 26.


G Protein-Coupled Receptor Kinases: Crucial Regulators of Blood Pressure.

Yang J, Villar VA, Armando I, Jose PA, Zeng C.

J Am Heart Assoc. 2016 Jul 7;5(7). pii: e003519. doi: 10.1161/JAHA.116.003519. Review. No abstract available.


Localization and signaling of GPCRs in lipid rafts.

Villar VA, Cuevas S, Zheng X, Jose PA.

Methods Cell Biol. 2016;132:3-23. doi: 10.1016/bs.mcb.2015.11.008. Epub 2016 Feb 10.


Human GRK4γ142V Variant Promotes Angiotensin II Type I Receptor-Mediated Hypertension via Renal Histone Deacetylase Type 1 Inhibition.

Wang Z, Zeng C, Villar VA, Chen SY, Konkalmatt P, Wang X, Asico LD, Jones JE, Yang Y, Sanada H, Felder RA, Eisner GM, Weir MR, Armando I, Jose PA.

Hypertension. 2016 Feb;67(2):325-34. doi: 10.1161/HYPERTENSIONAHA.115.05962. Epub 2015 Dec 14.


Genomics and Pharmacogenomics of Salt-sensitive Hypertension.

Armando I, Villar VA, Jose PA.

Curr Hypertens Rev. 2015;11(1):49-56. Review.


Role of nuclear factor erythroid 2-related factor 2 in the oxidative stress-dependent hypertension associated with the depletion of DJ-1.

Cuevas S, Yang Y, Konkalmatt P, Asico LD, Feranil J, Jones J, Villar VA, Armando I, Jose PA.

Hypertension. 2015 Jun;65(6):1251-7. doi: 10.1161/HYPERTENSIONAHA.114.04525. Epub 2015 Apr 20.


G protein-coupled receptor kinase 4: role in hypertension.

Yang J, Villar VA, Jones JE, Jose PA, Zeng C.

Hypertension. 2015 Jun;65(6):1148-55. doi: 10.1161/HYPERTENSIONAHA.115.05189. Epub 2015 Apr 13. Review. No abstract available.


Sorting nexin 5 and dopamine d1 receptor regulate the expression of the insulin receptor in human renal proximal tubule cells.

Li F, Yang J, Jones JE, Villar VA, Yu P, Armando I, Felder RA, Jose PA.

Endocrinology. 2015 Jun;156(6):2211-21. doi: 10.1210/en.2014-1638. Epub 2015 Mar 31.


Genomics and pharmacogenomics of salt-sensitive hypertension Minireview.

Armando I, Villar VA, Jose PA.

Curr Hypertens Rev. 2015;11(1):49-56.


Dopamine D₁-like receptors regulate the α₁A-adrenergic receptor in human renal proximal tubule cells and D₁-like dopamine receptor knockout mice.

Ennis RC, Asico LD, Armando I, Yang J, Feranil JB, Jurgens JA, Escano CS Jr, Yu P, Wang X, Sibley DR, Jose PA, Villar VA.

Am J Physiol Renal Physiol. 2014 Dec 1;307(11):F1238-48. doi: 10.1152/ajprenal.00119.2014. Epub 2014 Oct 22.


D1-like dopamine receptors downregulate Na+-K+-ATPase activity and increase cAMP production in the posterior gills of the blue crab Callinectes sapidus.

Arnaldo FB, Villar VA, Konkalmatt PR, Owens SA, Asico LD, Jones JE, Yang J, Lovett DL, Armando I, Jose PA, Concepcion GP.

Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15;307(6):R634-42. doi: 10.1152/ajpregu.00555.2013. Epub 2014 Jul 30.


Differential dopamine receptor subtype regulation of adenylyl cyclases in lipid rafts in human embryonic kidney and renal proximal tubule cells.

Yu P, Sun M, Villar VA, Zhang Y, Weinman EJ, Felder RA, Jose PA.

Cell Signal. 2014 Nov;26(11):2521-9. doi: 10.1016/j.cellsig.2014.07.003. Epub 2014 Jul 15.


Sestrin2 decreases renal oxidative stress, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of reactive oxygen species production.

Yang Y, Cuevas S, Yang S, Villar VA, Escano C, Asico L, Yu P, Jiang X, Weinman EJ, Armando I, Jose PA.

Hypertension. 2014 Oct;64(4):825-32. doi: 10.1161/HYPERTENSIONAHA.114.03840. Epub 2014 Jul 14.

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