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Items: 1 to 20 of 316

1.

Imaging of dehydration in particulate matter using Raman line-focus microscopy.

Okeyo PO, Ilchenko O, Slipets R, Larsen PE, Boisen A, Rades T, Rantanen J.

Sci Rep. 2019 May 17;9(1):7525. doi: 10.1038/s41598-019-43959-0.

2.

Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration.

Tandrup Schmidt S, Line Olsen C, Franzyk H, Wørzner K, Smith Korsholm K, Rades T, Andersen P, Foged C, Christensen D.

Eur J Pharm Biopharm. 2019 May 2. pii: S0939-6411(18)31257-8. doi: 10.1016/j.ejpb.2019.04.020. [Epub ahead of print]

3.

Direct Measurement of Amorphous Solubility.

Štukelj J, Svanbäck S, Agopov M, Löbmann K, Strachan CJ, Rades T, Yliruusi J.

Anal Chem. 2019 May 14. doi: 10.1021/acs.analchem.9b01378. [Epub ahead of print]

PMID:
31050887
4.

Spectroscopic evidence of tertiary structural differences between insulin molecules in fibrils.

Schack MM, Dahl K, Rades T, Groenning M, Carpenter JF.

J Pharm Sci. 2019 Apr 23. pii: S0022-3549(19)30251-5. doi: 10.1016/j.xphs.2019.04.018. [Epub ahead of print]

PMID:
31026447
5.

Inhalable co-amorphous budesonide-arginine dry powders prepared by spray drying.

Lu W, Rades T, Rantanen J, Yang M.

Int J Pharm. 2019 Apr 15;565:1-8. doi: 10.1016/j.ijpharm.2019.04.036. [Epub ahead of print]

PMID:
30999050
6.

Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions.

Blaabjerg LI, Bulduk B, Lindenberg E, Löbmann K, Rades T, Grohganz H.

J Pharm Sci. 2019 Mar 13. pii: S0022-3549(19)30151-0. doi: 10.1016/j.xphs.2019.02.028. [Epub ahead of print]

PMID:
30878513
7.

Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects.

Bergström CAS, Box K, Holm R, Matthews W, McAllister M, Müllertz A, Rades T, Schäfer KJ, Teleki A.

Eur J Pharm Biopharm. 2019 Jun;139:101-114. doi: 10.1016/j.ejpb.2019.03.011. Epub 2019 Mar 9. Review.

PMID:
30862481
8.

Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy.

Leng D, Kissi EO, Löbmann K, Thanki K, Fattal E, Rades T, Foged C, Yang M.

AAPS PharmSciTech. 2019 Mar 7;20(3):137. doi: 10.1208/s12249-019-1344-9.

PMID:
30847607
9.

Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes.

Li T, Nowell CJ, Cipolla D, Rades T, Boyd BJ.

Mol Pharm. 2019 Apr 1;16(4):1775-1781. doi: 10.1021/acs.molpharmaceut.8b01308. Epub 2019 Feb 27.

PMID:
30810323
10.

Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations.

Schack MM, Møller EH, Friderichsen AV, Carpenter JF, Rades T, Groenning M.

J Pharm Sci. 2019 Mar;108(3):1117-1129. doi: 10.1016/j.xphs.2018.10.028. Epub 2018 Oct 26.

PMID:
30773199
11.

Exploring the utility of the Chasing Principle: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension.

Siqueira Jørgensen S, Rades T, Mu H, Graeser K, Müllertz A.

Acta Pharm Sin B. 2019 Jan;9(1):194-201. doi: 10.1016/j.apsb.2018.07.004. Epub 2018 Jul 7.

12.

Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy.

Bohr A, Nascimento TL, Harmankaya N, Weisser JJ, Wang Y, Grohganz H, Rades T, Löbmann K.

Molecules. 2019 Jan 11;24(2). pii: E266. doi: 10.3390/molecules24020266.

13.

In situ co-amorphisation in coated tablets - The combination of carvedilol with aspartic acid during immersion in an acidic medium.

Petry I, Löbmann K, Grohganz H, Rades T, Leopold CS.

Int J Pharm. 2019 Mar 10;558:357-366. doi: 10.1016/j.ijpharm.2018.12.091. Epub 2019 Jan 12.

PMID:
30641182
14.

Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations.

Kasten G, Duarte Í, Paisana M, Löbmann K, Rades T, Grohganz H.

Pharmaceutics. 2019 Jan 9;11(1). pii: E24. doi: 10.3390/pharmaceutics11010024.

15.

Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems.

Wu W, Wang Y, Löbmann K, Grohganz H, Rades T.

Mol Pharm. 2019 Mar 4;16(3):1294-1304. doi: 10.1021/acs.molpharmaceut.8b01229. Epub 2019 Jan 25.

PMID:
30624075
16.

Co-former selection for co-amorphous drug-amino acid formulations.

Kasten G, Löbmann K, Grohganz H, Rades T.

Int J Pharm. 2019 Feb 25;557:366-373. doi: 10.1016/j.ijpharm.2018.12.036. Epub 2018 Dec 19.

PMID:
30578980
17.

Evaluation of the effects of spray drying parameters for producing cubosome powder precursors.

von Halling Laier C, Sonne Alstrøm T, Travers Bargholz M, Bjerg Sjøltov P, Rades T, Boisen A, Nielsen LH.

Eur J Pharm Biopharm. 2019 Feb;135:44-48. doi: 10.1016/j.ejpb.2018.12.008. Epub 2018 Dec 18.

PMID:
30576708
18.

Microcontainers for protection of oral vaccines, in vitro and in vivo evaluation.

von Halling Laier C, Gibson B, Moreno JAS, Rades T, Hook S, Nielsen LH, Boisen A.

J Control Release. 2019 Jan 28;294:91-101. doi: 10.1016/j.jconrel.2018.11.030. Epub 2018 Dec 12.

PMID:
30550938
19.

Whey proteins as stabilizers in amorphous solid dispersions.

Mishra J, Bohr A, Rades T, Grohganz H, Löbmann K.

Eur J Pharm Sci. 2019 Feb 1;128:144-151. doi: 10.1016/j.ejps.2018.12.002. Epub 2018 Dec 4.

PMID:
30528387
20.

Solid State Characterization of Ciprofloxacin Liposome Nanocrystals.

Li T, Mudie S, Cipolla D, Rades T, Boyd BJ.

Mol Pharm. 2019 Jan 7;16(1):184-194. doi: 10.1021/acs.molpharmaceut.8b00940. Epub 2018 Nov 29.

PMID:
30495965

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