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Items: 1 to 20 of 64

1.

The dual roles of RPE65 S-palmitoylation in membrane association and visual cycle function.

Uppal S, Liu T, Poliakov E, Gentleman S, Redmond TM.

Sci Rep. 2019 Mar 26;9(1):5218. doi: 10.1038/s41598-019-41501-w.

2.

Volatile Evolution of Long Non-Coding RNA Repertoire in Retinal Pigment Epithelium: Insights from Comparison of Bovine and Human RNA Expression Profiles.

Postnikova OA, Rogozin IB, Samuel W, Nudelman G, Babenko VN, Poliakov E, Redmond TM.

Genes (Basel). 2019 Mar 8;10(3). pii: E205. doi: 10.3390/genes10030205.

3.

Aberrant RNA splicing is the major pathogenic effect in a knock-in mouse model of the dominantly inherited c.1430A>G human RPE65 mutation.

Li Y, Furhang R, Ray A, Duncan T, Soucy J, Mahdi R, Chaitankar V, Gieser L, Poliakov E, Qian H, Liu P, Dong L, Rogozin IB, Redmond TM.

Hum Mutat. 2019 Apr;40(4):426-443. doi: 10.1002/humu.23706. Epub 2019 Jan 25.

PMID:
30628748
4.

Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration.

Lenis TL, Hu J, Ng SY, Jiang Z, Sarfare S, Lloyd MB, Esposito NJ, Samuel W, Jaworski C, Bok D, Finnemann SC, Radeke MJ, Redmond TM, Travis GH, Radu RA.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11120-E11127. doi: 10.1073/pnas.1802519115. Epub 2018 Nov 5.

5.

Proinflammatory cytokine interferon-γ increases the expression of BANCR, a long non-coding RNA, in retinal pigment epithelial cells.

Kutty RK, Samuel W, Duncan T, Postnikova O, Jaworski C, Nagineni CN, Redmond TM.

Cytokine. 2018 Apr;104:147-150. doi: 10.1016/j.cyto.2017.10.009. Epub 2017 Oct 18.

6.

Phylogenetic analysis of the metazoan carotenoid oxygenase superfamily: a new ancestral gene assemblage of BCO-like (BCOL) proteins.

Poliakov E, Soucy J, Gentleman S, Rogozin IB, Redmond TM.

Sci Rep. 2017 Oct 16;7(1):13192. doi: 10.1038/s41598-017-13521-x.

7.

RPE65 takes on another role in the vertebrate retina.

Redmond TM.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10818-10820. doi: 10.1073/pnas.1715064114. Epub 2017 Oct 2. No abstract available.

8.
9.

Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration.

Ma H, Yang F, Butler MR, Belcher J, Redmond TM, Placzek AT, Scanlan TS, Ding XQ.

FASEB J. 2017 Aug;31(8):3425-3438. doi: 10.1096/fj.201601166RR. Epub 2017 Apr 20.

10.

Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells.

Samuel W, Jaworski C, Postnikova OA, Kutty RK, Duncan T, Tan LX, Poliakov E, Lakkaraju A, Redmond TM.

Mol Vis. 2017 Mar 5;23:60-89. eCollection 2017.

11.

Proinflammatory cytokines decrease the expression of genes critical for RPE function.

Kutty RK, Samuel W, Boyce K, Cherukuri A, Duncan T, Jaworski C, Nagineni CN, Redmond TM.

Mol Vis. 2016 Oct 8;22:1156-1168. eCollection 2016.

12.

Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration.

Yang F, Ma H, Belcher J, Butler MR, Redmond TM, Boye SL, Hauswirth WW, Ding XQ.

FASEB J. 2016 Dec;30(12):4313-4325. Epub 2016 Sep 13.

13.

Inhibition of RPE65 Retinol Isomerase Activity by Inhibitors of Lipid Metabolism.

Eroglu A, Gentleman S, Poliakov E, Redmond TM.

J Biol Chem. 2016 Mar 4;291(10):4966-73. doi: 10.1074/jbc.M115.685651. Epub 2015 Dec 30.

14.

A History of the Classical Visual Cycle.

Wright CB, Redmond TM, Nickerson JM.

Prog Mol Biol Transl Sci. 2015;134:433-48. doi: 10.1016/bs.pmbts.2015.06.009. Epub 2015 Jul 3. Review.

PMID:
26310169
15.

Mouse model of human RPE65 P25L hypomorph resembles wild type under normal light rearing but is fully resistant to acute light damage.

Li Y, Yu S, Duncan T, Li Y, Liu P, Gene E, Cortes-Pena Y, Qian H, Dong L, Redmond TM.

Hum Mol Genet. 2015 Aug 1;24(15):4417-28. doi: 10.1093/hmg/ddv178. Epub 2015 May 13.

16.

Resveratrol attenuates CXCL11 expression induced by proinflammatory cytokines in retinal pigment epithelial cells.

Kutty RK, Samuel W, Abay R, Cherukuri A, Nagineni CN, Duncan T, Jaworski C, Vijayasarathy C, Redmond TM.

Cytokine. 2015 Aug;74(2):335-8. doi: 10.1016/j.cyto.2015.03.016. Epub 2015 Apr 15.

17.

Multiple A2E treatments lead to melanization of rod outer segment-challenged ARPE-19 cells.

Poliakov E, Strunnikova NV, Jiang JK, Martinez B, Parikh T, Lakkaraju A, Thomas C, Brooks BP, Redmond TM.

Mol Vis. 2014 Mar 14;20:285-300. eCollection 2014.

18.

The Rpe65 rd12 allele exerts a semidominant negative effect on vision in mice.

Wright CB, Chrenek MA, Feng W, Getz SE, Duncan T, Pardue MT, Feng Y, Redmond TM, Boatright JH, Nickerson JM.

Invest Ophthalmol Vis Sci. 2014 Apr 17;55(4):2500-15. doi: 10.1167/iovs.13-13574.

19.

Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration.

Ma H, Thapa A, Morris L, Redmond TM, Baehr W, Ding XQ.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3602-7. doi: 10.1073/pnas.1317041111. Epub 2014 Feb 18.

20.

Fenretinide induces ubiquitin-dependent proteasomal degradation of stearoyl-CoA desaturase in human retinal pigment epithelial cells.

Samuel W, Kutty RK, Duncan T, Vijayasarathy C, Kuo BC, Chapa KM, Redmond TM.

J Cell Physiol. 2014 Aug;229(8):1028-38. doi: 10.1002/jcp.24527.

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