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Items: 1 to 20 of 40

1.

NMDA Receptor-Mediated Signaling Pathways Enhance Radiation Resistance, Survival and Migration in Glioblastoma Cells-A Potential Target for Adjuvant Radiotherapy.

Müller-Längle A, Lutz H, Hehlgans S, Rödel F, Rau K, Laube B.

Cancers (Basel). 2019 Apr 9;11(4). pii: E503. doi: 10.3390/cancers11040503.

2.

Arsenic Trioxide and (-)-Gossypol Synergistically Target Glioma Stem-Like Cells via Inhibition of Hedgehog and Notch Signaling.

Linder B, Wehle A, Hehlgans S, Bonn F, Dikic I, Rödel F, Seifert V, Kögel D.

Cancers (Basel). 2019 Mar 12;11(3). pii: E350. doi: 10.3390/cancers11030350.

3.

Radiation Sensitization of Basal Cell and Head and Neck Squamous Cell Carcinoma by the Hedgehog Pathway Inhibitor Vismodegib.

Hehlgans S, Booms P, Güllülü Ö, Sader R, Rödel C, Balermpas P, Rödel F, Ghanaati S.

Int J Mol Sci. 2018 Aug 23;19(9). pii: E2485. doi: 10.3390/ijms19092485.

4.

Ionizing Radiation Induces Morphological Changes and Immunological Modulation of Jurkat Cells.

Voos P, Fuck S, Weipert F, Babel L, Tandl D, Meckel T, Hehlgans S, Fournier C, Moroni A, Rödel F, Thiel G.

Front Immunol. 2018 Apr 30;9:922. doi: 10.3389/fimmu.2018.00922. eCollection 2018.

5.

Differential effects of α-catenin on the invasion and radiochemosensitivity of human colorectal cancer cells.

Förster S, Hehlgans S, Rödel F, Otto B, Cordes N.

Int J Oncol. 2018 Apr;52(4):1117-1128. doi: 10.3892/ijo.2018.4279. Epub 2018 Feb 21.

6.

Measuring Leukocyte Adhesion to (Primary) Endothelial Cells after Photon and Charged Particle Exposure with a Dedicated Laminar Flow Chamber.

Erbeldinger N, Rapp F, Ktitareva S, Wendel P, Bothe AS, Dettmering T, Durante M, Friedrich T, Bertulat B, Meyer S, Cardoso MC, Hehlgans S, Rödel F, Fournier C.

Front Immunol. 2017 Jun 1;8:627. doi: 10.3389/fimmu.2017.00627. eCollection 2017.

7.

Basics of Radiation Biology When Treating Hyperproliferative Benign Diseases.

Rödel F, Fournier C, Wiedemann J, Merz F, Gaipl US, Frey B, Keilholz L, Seegenschmiedt MH, Rödel C, Hehlgans S.

Front Immunol. 2017 May 3;8:519. doi: 10.3389/fimmu.2017.00519. eCollection 2017. Review.

8.

Silencing of the mRNA-binding protein HuR increases the sensitivity of colorectal cancer cells to ionizing radiation through upregulation of caspase-2.

Badawi A, Hehlgans S, Pfeilschifter J, Rödel F, Eberhardt W.

Cancer Lett. 2017 May 1;393:103-112. doi: 10.1016/j.canlet.2017.02.010. Epub 2017 Feb 20.

PMID:
28219770
9.

Interference with the HSF1/HSP70/BAG3 Pathway Primes Glioma Cells to Matrix Detachment and BH3 Mimetic-Induced Apoptosis.

Antonietti P, Linder B, Hehlgans S, Mildenberger IC, Burger MC, Fulda S, Steinbach JP, Gessler F, Rödel F, Mittelbronn M, Kögel D.

Mol Cancer Ther. 2017 Jan;16(1):156-168. doi: 10.1158/1535-7163.MCT-16-0262. Epub 2016 Oct 24.

10.

Comprehensive analysis of signal transduction in three-dimensional ECM-based tumor cell cultures.

Eke I, Hehlgans S, Zong Y, Cordes N.

J Biol Methods. 2015;2(4). pii: e31. Epub 2015 Nov 17.

11.

3D matrix-based cell cultures: Automated analysis of tumor cell survival and proliferation.

Eke I, Hehlgans S, Sandfort V, Cordes N.

Int J Oncol. 2016 Jan;48(1):313-21. doi: 10.3892/ijo.2015.3230. Epub 2015 Nov 4.

12.

The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis.

Hehlgans S, Oppermann J, Reichert S, Fulda S, Rödel C, Rödel F.

Radiat Oncol. 2015 Sep 17;10:198. doi: 10.1186/s13014-015-0507-4.

13.

The role of recent nanotechnology in enhancing the efficacy of radiation therapy.

Bergs JW, Wacker MG, Hehlgans S, Piiper A, Multhoff G, Rödel C, Rödel F.

Biochim Biophys Acta. 2015 Aug;1856(1):130-43. doi: 10.1016/j.bbcan.2015.06.008. Epub 2015 Jul 2. Review.

PMID:
26142869
14.

Study of the anti-inflammatory effects of low-dose radiation: The contribution of biphasic regulation of the antioxidative system in endothelial cells.

Large M, Hehlgans S, Reichert S, Gaipl US, Fournier C, Rödel C, Weiss C, Rödel F.

Strahlenther Onkol. 2015 Sep;191(9):742-9. doi: 10.1007/s00066-015-0848-9. Epub 2015 Jun 8.

PMID:
26051282
15.

Modulation of inflammation by low and high doses of ionizing radiation: Implications for benign and malign diseases.

Frey B, Hehlgans S, Rödel F, Gaipl US.

Cancer Lett. 2015 Nov 28;368(2):230-7. doi: 10.1016/j.canlet.2015.04.010. Epub 2015 Apr 14. Review.

PMID:
25888451
16.

Mitotic arrest and slippage induced by pharmacological inhibition of Polo-like kinase 1.

Raab M, Krämer A, Hehlgans S, Sanhaji M, Kurunci-Csacsko E, Dötsch C, Bug G, Ottmann O, Becker S, Pachl F, Kuster B, Strebhardt K.

Mol Oncol. 2015 Jan;9(1):140-54. doi: 10.1016/j.molonc.2014.07.020. Epub 2014 Aug 11.

17.

A non-linear detection of phospho-histone H2AX in EA.hy926 endothelial cells following low-dose X-irradiation is modulated by reactive oxygen species.

Large M, Reichert S, Hehlgans S, Fournier C, Rödel C, Rödel F.

Radiat Oncol. 2014 Mar 22;9:80. doi: 10.1186/1748-717X-9-80.

18.

The novel HDAC inhibitor NDACI054 sensitizes human cancer cells to radiotherapy.

Hehlgans S, Storch K, Lange I, Cordes N.

Radiother Oncol. 2013 Oct;109(1):126-32. doi: 10.1016/j.radonc.2013.08.023. Epub 2013 Sep 20.

PMID:
24060178
19.

Targeting by cmHsp70.1-antibody coated and survivin miRNA plasmid loaded nanoparticles to radiosensitize glioblastoma cells.

Gaca S, Reichert S, Multhoff G, Wacker M, Hehlgans S, Botzler C, Gehrmann M, Rödel C, Kreuter J, Rödel F.

J Control Release. 2013 Nov 28;172(1):201-206. doi: 10.1016/j.jconrel.2013.08.020. Epub 2013 Sep 2.

PMID:
24008150
20.

Double targeting of Survivin and XIAP radiosensitizes 3D grown human colorectal tumor cells and decreases migration.

Hehlgans S, Petraki C, Reichert S, Cordes N, Rödel C, Rödel F.

Radiother Oncol. 2013 Jul;108(1):32-9. doi: 10.1016/j.radonc.2013.06.006. Epub 2013 Jul 3.

PMID:
23830189

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