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Items: 1 to 20 of 30

1.

Immunohistochemical Characterization of Procaspase-3 Overexpression as a Druggable Target With PAC-1, a Procaspase-3 Activator, in Canine and Human Brain Cancers.

Schlein LJ, Fadl-Alla B, Pondenis HC, Lezmi S, Eberhart CG, LeBlanc AK, Dickinson PJ, Hergenrother PJ, Fan TM.

Front Oncol. 2019 Feb 25;9:96. doi: 10.3389/fonc.2019.00096. eCollection 2019.

2.

Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models.

Elliott M, Favre-Guilmard C, Liu SM, Maignel J, Masuyer G, Beard M, Boone C, Carré D, Kalinichev M, Lezmi S, Mir I, Nicoleau C, Palan S, Perier C, Raban E, Zhang S, Dong M, Stenmark P, Krupp J.

Sci Adv. 2019 Jan 16;5(1):eaau7196. doi: 10.1126/sciadv.aau7196. eCollection 2019 Jan.

3.

The Expanding Therapeutic Utility of Botulinum Neurotoxins.

Fonfria E, Maignel J, Lezmi S, Martin V, Splevins A, Shubber S, Kalinichev M, Foster K, Picaut P, Krupp J.

Toxins (Basel). 2018 May 18;10(5). pii: E208. doi: 10.3390/toxins10050208. Review.

4.

Extract of Ginkgo biloba exacerbates liver metastasis in a mouse colon cancer Xenograft model.

Wang H, Wu X, Lezmi S, Li Q, Helferich WG, Xu Y, Chen H.

BMC Complement Altern Med. 2017 Dec 2;17(1):516. doi: 10.1186/s12906-017-2014-7.

5.

Pathology in Practice.

Le Boedec K, Phillips H, Zamprogno H, Joslyn S, O'Brien RT, Lezmi S.

J Am Vet Med Assoc. 2017 May 1;250(9):993-995. doi: 10.2460/javma.250.9.993. No abstract available.

PMID:
28414594
6.

Selective in vivo metabolic cell-labeling-mediated cancer targeting.

Wang H, Wang R, Cai K, He H, Liu Y, Yen J, Wang Z, Xu M, Sun Y, Zhou X, Yin Q, Tang L, Dobrucki IT, Dobrucki LW, Chaney EJ, Boppart SA, Fan TM, Lezmi S, Chen X, Yin L, Cheng J.

Nat Chem Biol. 2017 Apr;13(4):415-424. doi: 10.1038/nchembio.2297. Epub 2017 Feb 13.

7.

Atypical bromethalin intoxication in a dog: pathologic features and identification of an isomeric breakdown product.

Bates MC, Roady P, Lehner AF, Buchweitz JP, Heggem-Perry B, Lezmi S.

BMC Vet Res. 2015 Sep 28;11:244. doi: 10.1186/s12917-015-0554-y.

8.

Pathology in Practice. Necrotizing leukoencephalitis (NLE).

Eberly JA, Hague DW, Singh K, Lezmi S.

J Am Vet Med Assoc. 2015 Aug 15;247(4):361-3. doi: 10.2460/javma.247.4.361. No abstract available.

PMID:
26225607
9.

High-fat diet caused widespread epigenomic differences on hepatic methylome in rat.

Zhang Y, Wang H, Zhou D, Moody L, Lezmi S, Chen H, Pan YX.

Physiol Genomics. 2015 Oct;47(10):514-23. doi: 10.1152/physiolgenomics.00110.2014. Epub 2015 Jul 21.

PMID:
26199400
11.

In utero growth restriction and catch-up adipogenesis after developmental di (2-ethylhexyl) phthalate exposure cause glucose intolerance in adult male rats following a high-fat dietary challenge.

Strakovsky RS, Lezmi S, Shkoda I, Flaws JA, Helferich WG, Pan YX.

J Nutr Biochem. 2015 Nov;26(11):1208-20. doi: 10.1016/j.jnutbio.2015.05.012. Epub 2015 Jun 20.

12.

Redox-Responsive Self-Assembled Chain-Shattering Polymeric Therapeutics.

Cai K, Yen J, Yin Q, Liu Y, Song Z, Lezmi S, Zhang Y, Yang X, Helferich WG, Cheng J.

Biomater Sci. 2015 Jul;3(7):1061-5. doi: 10.1039/C4BM00452C.

13.

Deoxynybomycins inhibit mutant DNA gyrase and rescue mice infected with fluoroquinolone-resistant bacteria.

Parkinson EI, Bair JS, Nakamura BA, Lee HY, Kuttab HI, Southgate EH, Lezmi S, Lau GW, Hergenrother PJ.

Nat Commun. 2015 Apr 24;6:6947. doi: 10.1038/ncomms7947.

14.

Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis.

Strakovsky RS, Wang H, Engeseth NJ, Flaws JA, Helferich WG, Pan YX, Lezmi S.

Toxicol Appl Pharmacol. 2015 Apr 15;284(2):101-12. doi: 10.1016/j.taap.2015.02.021. Epub 2015 Mar 5.

15.

Investigating the optimal size of anticancer nanomedicine.

Tang L, Yang X, Yin Q, Cai K, Wang H, Chaudhury I, Yao C, Zhou Q, Kwon M, Hartman JA, Dobrucki IT, Dobrucki LW, Borst LB, Lezmi S, Helferich WG, Ferguson AL, Fan TM, Cheng J.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15344-9. doi: 10.1073/pnas.1411499111. Epub 2014 Oct 14.

16.

Pathology in practice. Chondro-osseous metaplasia consistent with synovial chondromatosisin a great horned owl.

Xie S, Nevis J, Lezmi S.

J Am Vet Med Assoc. 2014 Oct 1;245(7):767-9. doi: 10.2460/javma.245.7.767. No abstract available.

PMID:
25229527
17.

A mechanically-induced colon cancer cell population shows increased metastatic potential.

Tang X, Kuhlenschmidt TB, Li Q, Ali S, Lezmi S, Chen H, Pires-Alves M, Laegreid WW, Saif TA, Kuhlenschmidt MS.

Mol Cancer. 2014 May 29;13:131. doi: 10.1186/1476-4598-13-131.

18.

A neonatal piglet model for investigating brain and cognitive development in small for gestational age human infants.

Radlowski EC, Conrad MS, Lezmi S, Dilger RN, Sutton B, Larsen R, Johnson RW.

PLoS One. 2014 Mar 17;9(3):e91951. doi: 10.1371/journal.pone.0091951. eCollection 2014.

19.

Genistein exposure during the early postnatal period favors the development of obesity in female, but not male rats.

Strakovsky RS, Lezmi S, Flaws JA, Schantz SL, Pan YX, Helferich WG.

Toxicol Sci. 2014 Mar;138(1):161-74. doi: 10.1093/toxsci/kft331. Epub 2013 Dec 21.

20.

Chloroquine causes similar electroretinogram modifications, neuronal phospholipidosis and marked impairment of synaptic vesicle transport in albino and pigmented rats.

Lezmi S, Rokh N, Saint-Macary G, Pino M, Sallez V, Thevenard F, Roome N, Rosolen S.

Toxicology. 2013 Jun 7;308:50-9. doi: 10.1016/j.tox.2013.03.012. Epub 2013 Apr 5.

PMID:
23567313

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